ChemicalBook >> CAS DataBase List >>7-BROMO-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER

7-BROMO-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER

7-BROMO-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER structure

CAS No.: 179943-57-8

Chemical Name:: 7-BROMO-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER

Synonyms: 7-bromo-4-hydroxyquinoline-3-carboxylate;Ethyl7-BroMo-4-hydroxy-3-quinolinecarboxylate;Ethyl 4-hydroxy-7-broMoquinoline-3-carboxylate;Ethyl 7-bromo-4-hydroxyquinoline-3-carboxylate;3-Quinolinecarboxylicacid, 7-bromo-4-hydroxy-, ethy..;3-Quinolinecarboxylic acid, 7-bromo-4-hydroxy-, ethyl ester;ethyl 7-bromo-1,4-dihydro-4-oxo-3-quinolinecarboxylate, 95%;7-BROMO-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER

CBNumber:: CB62450003

Molecular Formula:: C12H10BrNO3

Molecular Weight:: 296.12

MDL Number:: MFCD00487280

MOL File:: 179943-57-8.mol

MSDS File:: SDS

Last updated:2026-05-28 03:54:57

Product description	Number	Pack Size	Price
Ethyl 7-bromo-4-hydroxyquinoline-3-carboxylate 95%	OR183498	1g	$48
Ethyl 7-bromo-4-hydroxyquinoline-3-carboxylate 95%	OR183498	5g	$85
Ethyl 7-bromo-4-hydroxyquinoline-3-carboxylate 95%	OR183498	25g	$162
Ethyl 7-bromo-4-hydroxyquinoline-3-carboxylate	073257	1.00g	$416
Ethyl 7-bromo-4-hydroxyquinoline-3-carboxylate	073257	5.00g	$1197
More product size

Request For Quotation

7-BROMO-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER Properties

Melting point	307-309 °C
Boiling point	385.5±37.0 °C(Predicted)
Density	1.593±0.06 g/cm3(Predicted)
storage temp.	Inert atmosphere,Room Temperature
pka	2.16±0.50(Predicted)
Appearance	White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H332-H312-H319-H315-H302-H335
Precautionary statements	P264-P280-P302+P352-P321-P332+P313-P362-P261-P271-P304+P340-P312-P280-P302+P352-P312-P322-P363-P501-P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P
HS Code	2933499090

7-BROMO-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER price More Price(41)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Apolloscientific	OR183498	Ethyl 7-bromo-4-hydroxyquinoline-3-carboxylate 95%	179943-57-8	1g	$48	2026-06-04	Buy
Apolloscientific	OR183498	Ethyl 7-bromo-4-hydroxyquinoline-3-carboxylate 95%	179943-57-8	5g	$85	2026-06-04	Buy
Apolloscientific	OR183498	Ethyl 7-bromo-4-hydroxyquinoline-3-carboxylate 95%	179943-57-8	25g	$162	2026-06-04	Buy
Matrix Scientific	073257	Ethyl 7-bromo-4-hydroxyquinoline-3-carboxylate	179943-57-8	1.00g	$416	2026-05-18	Buy
Matrix Scientific	073257	Ethyl 7-bromo-4-hydroxyquinoline-3-carboxylate	179943-57-8	5.00g	$1197	2026-05-18	Buy

Product number	Packaging	Price	Buy
OR183498	1g	$48	Buy
OR183498	5g	$85	Buy
OR183498	25g	$162	Buy
073257	1.00g	$416	Buy
073257	5.00g	$1197	Buy

7-BROMO-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER Chemical Properties,Uses,Production

Synthesis

2-[[(3-Bromophenyl)amino]methylene]propanedioic Acid 1,3-Diethyl Ester

351893-47-5

ethyl 7-bromo-4-oxo-1,4-dihydroquinoline-3-carboxylate

208580-23-8

Dowtherm (50 mL) was added to a 100 mL two-necked round-bottomed flask and heated to 250 °C in a sand bath. Maintaining this temperature, diethyl {[(3-bromophenyl)amino]methylene}malonate (Intermediate 32, 10.0 g, 29.2 mmol) was added to the reaction system and the reaction was continued at 250 °C for 1 hour. After completion of the reaction, the reaction mixture was cooled to room temperature and a white solid was collected by filtration and dried to give ethyl 7-bromo-4-oxo-1,4-dihydroquinoline-3-carboxylate 6.0 g in 69.3% yield. The product was characterized by 1H NMR (400 MHz, DMSO-d6): δ 1.07 (t, 3H), 1.22 (s, 12H), 3.16 (q, 2H), 7.29 (m, 1H), 7.31 (d, 2H), 7.61 (s, 1H), 7.88 (s, 1H), 8.31 (s, 1H), 8.65 (s, 1H), and 9.44 (s, 1H).

References

[1] Journal of Medicinal Chemistry, 2015, vol. 58, # 14, p. 5522 - 5537
[2] Patent: WO2009/147433, 2009, A1. Location in patent: Page/Page column 279
[3] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 15, p. 4790 - 4800
[4] Bioorganic and Medicinal Chemistry Letters, 2006, vol. 16, # 4, p. 1010 - 1013
[5] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 15, p. 5055 - 5058

7-BROMO-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER synthesis

Synthesis of 7-BROMO-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER from 2-[[(3-Bromophenyl)amino]methylene]propanedioic Acid 1,3-Diethyl Ester

7-BROMO-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER Preparation Products And Raw materials

Raw materials

2-[[(3-Bromophenyl)amino]methylene]propanedioic Acid 1,3-Diethyl Ester 3-Bromoaniline Diethyl ethoxymethylenemalonate

Preparation Products

7-BROMO-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER Suppliers

Global( 83)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29626	60
CONIER CHEM AND PHARMA LIMITED		sales@conier.com	China	49906	58
career henan chemical co	+86-0371-86658258	factory@coreychem.com	China	29780	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 17705817739	info@dycnchem.com	China	52693	58
GIHI CHEMICALS CO.,LIMITED	+86-571-86217390; +8618058761490	info@gihichemicals.com	China	49860	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850 +86-15355479329	market18@leapchem.com	China	43303	58
Aladdin Scientific		tp@aladdinsci.com	United States	54746	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131885	58
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Bide Pharmatech Ltd.	400-164-7117 18317119277	product02@bidepharm.com	China	40000	60

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
GIHI CHEMICALS CO.,LIMITED	58
HANGZHOU LEAP CHEM CO., LTD.	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58
Energy Chemical	61
Bide Pharmatech Ltd.	60

View Lastest Price from 7-BROMO-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-01-09	7-BROMO-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER 179943-57-8	$6.68	1KG	99%	1kg-1000kg	Career Henan Chemical Co

7-BROMO-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER
179943-57-8
$6.68
99%
Career Henan Chemical Co

7-BROMO-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER Spectrum

7-BROMO-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER(179943-57-8)¹HNMR

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7-BROMO-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER Ethyl 7-bromo-4-hydroxyquinoline-3-carboxylate Ethyl 4-hydroxy-7-broMoquinoline-3-carboxylate Ethyl7-BroMo-4-hydroxy-3-quinolinecarboxylate 7-bromo-4-hydroxyquinoline-3-carboxylate 3-Quinolinecarboxylic acid, 7-bromo-4-hydroxy-, ethyl ester 3-Quinolinecarboxylicacid, 7-bromo-4-hydroxy-, ethy.. ethyl 7-bromo-1,4-dihydro-4-oxo-3-quinolinecarboxylate, 95% 179943-57-8