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4-(2-CHLOROACETYL)MORPHOLINE

4-(2-CHLOROACETYL)MORPHOLINE structure

CAS No.: 1440-61-5

Chemical Name:: 4-(2-CHLOROACETYL)MORPHOLINE

Synonyms: NSC 54542;BUTTPARK 30\04-53;AKOS BBS-00000944;TIMTEC-BB SBB005580;LABOTEST-BB LT00000129;N-(CHLOROACETYL)MORPHOLINE;4-(chloroacetyl)-morpholin;chloroaceticacidmorpholide;4-(CHLOROACETYL)MORPHOLINE;4-(2-CHLOROACETYL)MORPHOLINE

CBNumber:: CB6250656

Molecular Formula:: C6H10ClNO2

Molecular Weight:: 163.6

MDL Number:: MFCD00721939

MOL File:: 1440-61-5.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:44

Product description	Number	Pack Size	Price
2-Chloro-1-morpholinoethan-1-one min. 98.0 %	C2588	5G	$54
2-Chloro-1-morpholinoethan-1-one min. 98.0 %	C2588	25G	$162
4-(Chloroacetyl)morpholine	C363700	10g	$875
4-(2-CHLOROACETYL)MORPHOLINE 95.00%	HCH0022098	25G	$1257.8
N-(Chloroacetyl)morpholine 98%	005874	1Kg	$1490
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4-(2-CHLOROACETYL)MORPHOLINE Properties

Melting point	26-30 °C
Boiling point	152-160 °C(Press: 6 Torr)
Density	1.257 g/mL at 25 °C
refractive index	n20/D 1.512
Flash point	110 °C
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
pka	-1.26±0.20(Predicted)
form	Solid
color	Colourless to Pale Yellow Oil
Stability	Hygroscopic
CAS DataBase Reference	1440-61-5(CAS DataBase Reference)
EPA Substance Registry System	Morpholine, 4-(chloroacetyl)- (1440-61-5)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05,GHS07

Signal word

Warning

Hazard statements

H314-H318-H302-H319

Precautionary statements

P305+P351+P338-P260h-P301+P330+P331-P303+P361+P353-P405-P501a

Hazard Codes

Xi,Xn

Risk Statements

36/37/38-22

Safety Statements

26-36/37/39

RIDADR

UN3261

WGK Germany

Hazard Note

Irritant

HazardClass

PackingGroup

III

HS Code

29349990

NFPA 704

	0
2		0

4-(2-CHLOROACETYL)MORPHOLINE price More Price(29)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	C2588	2-Chloro-1-morpholinoethan-1-one min. 98.0 %	1440-61-5	5G	$54	2025-07-31	Buy
TCI Chemical	C2588	2-Chloro-1-morpholinoethan-1-one min. 98.0 %	1440-61-5	25G	$162	2025-07-31	Buy
TRC	C363700	4-(Chloroacetyl)morpholine	1440-61-5	10g	$875	2021-12-16	Buy
American Custom Chemicals Corporation	HCH0022098	4-(2-CHLOROACETYL)MORPHOLINE 95.00%	1440-61-5	25G	$1257.8	2021-12-16	Buy
Oakwood	005874	N-(Chloroacetyl)morpholine 98%	1440-61-5	1Kg	$1490	2021-12-16	Buy

Product number	Packaging	Price	Buy
C2588	5G	$54	Buy
C2588	25G	$162	Buy
C363700	10g	$875	Buy
HCH0022098	25G	$1257.8	Buy
005874	1Kg	$1490	Buy

4-(2-CHLOROACETYL)MORPHOLINE Chemical Properties,Uses,Production

Chemical Properties

Colorless liquid

Uses

The chloroacetyl derivatives are microbicides for adhesives, cellulose foams, oil emulsions, cooling water, etc.

Synthesis

110-91-8

79-04-9

1440-61-5

Step 1: Morpholine (1.00 mL, 11.5 mmol) and toluene (30 mL) were added to a dry three-necked flask equipped with a magnetic stirrer under nitrogen protection. Potassium carbonate (3.17 g, 22.9 mmol) was then added and stirred until completely dissolved. Chloroacetyl chloride (0.91 mL, 11.4 mmol) was slowly added dropwise under the cooling of an ice bath, and after completion of the dropwise addition, the ice bath was removed, the temperature was raised to 60 °C and the reaction was continuously stirred for 2 hours. After completion of the reaction, the reaction mixture was cooled to room temperature, filtered to remove insoluble solids, and the solids were washed with a small amount of toluene. The filtrate and washings were combined and concentrated under reduced pressure to remove the solvent to give N-chloroacetylmorpholine as a white solid (1.87 g, quantitative yield). The product was characterized by 1H-NMR (270 MHz, CDCl3): δ 3.51-3.54 (m, 2H), 3.62-3.65 (m, 2H), 3.68-3.74 (m, 4H), 4.07 (s, 2H).

References

[1] Patent: EP1650194, 2006, A1. Location in patent: Page/Page column 34
[2] Patent: WO2012/72019, 2012, A1. Location in patent: Page/Page column 71-72
[3] Molecules, 2015, vol. 20, # 11, p. 19984 - 20013
[4] Patent: WO2016/147144, 2016, A1. Location in patent: Page/Page column 222
[5] Journal of Medicinal Chemistry, 2009, vol. 52, # 21, p. 6660 - 6671

4-(2-CHLOROACETYL)MORPHOLINE Preparation Products And Raw materials

Raw materials

Morpholine Chloroacetyl chloride Chloroacetic anhydride Toluene Potassium carbonate

Preparation Products

2-CHLORO-N-CYCLOHEXYL-ACETAMIDE Pinaverium bromide 4-(2-MORPHOLIN-4-YL-2-OXO-ETHOXY)-BENZALDEHYDE teomorfolin 3-METHOXY-4-(2-MORPHOLIN-4-YL-2-OXO-ETHOXY)-BENZALDEHYDE

4-(2-CHLOROACETYL)MORPHOLINE Suppliers

Global( 181)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21597	55
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
Changzhou Ditong Chemical Co.,Ltd	+86-0519-88298848	info@edengenechem.com	China	2176	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29795	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30229	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
Win-Win chemical CO., Limited	+86-0086-577-64498589 +86-15355981851	sales@win-winchemical.com	China	14343	58

Supplier	Advantage
Henan Tianfu Chemical Co.,Ltd.	55
Jinan Carbotang Biotech Co.,Ltd.	58
Changzhou Ditong Chemical Co.,Ltd	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Career Henan Chemica Co	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Win-Win chemical CO., Limited	58

View Lastest Price from 4-(2-CHLOROACETYL)MORPHOLINE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-01-09	4-(2-CHLOROACETYL)MORPHOLINE 1440-61-5	US $1.00 / KG	1KG	99%	200kg	Career Henan Chemical Co

4-(2-CHLOROACETYL)MORPHOLINE
1440-61-5
US $1.00 / KG
99%
Career Henan Chemical Co

4-(2-CHLOROACETYL)MORPHOLINE Spectrum

4-(2-CHLOROACETYL)MORPHOLINE(1440-61-5)¹HNMR

1440-61-5(4-(2-CHLOROACETYL)MORPHOLINE)Related Search:

TIMTEC-BB SBB010861 4-(CHLOROACETYL)-2-METHYLMORPHOLINE 4-(2-chloropropanoyl)-2-methylmorpholine 4-(2-CHLOROACETYL)MORPHOLINE 4-[CHLORO(PHENYL)ACETYL]MORPHOLINE

2-Chloro-1-(morpholin-4-yl)ethan-1-one 4-(2-Chloroacetyl)morpholine 98% 2-Chloro-1-morpholinoethan-1-one, 95+% 2-CHLORO-1-MORPHOLIN-4-YL-ETHANONE >98% 4-(CHLOROACETYL)MORPHOLINE, 97+% 2-Chloro-1-(4-morpholinyl)ethanone, 2-Chloro-1-morpholinoethanone, 2-Morpholino-2-oxoethyl chloride, 4-Morpholinylcarbonylmethyl chloride, N-(Chloroacetyl)morpholine, Chloroacetic acid morpholide, Chloroacetic acid morpholine amide, Morpholine chloroacetamide 1-Morpholino-2-chloroethanone 2-Chloro-1-(4-Morpholinyl)ehanone 2-Chloro-1-Morpholino-1-ethanone 2-Chloro-1-Morpholinoethanone 4-Morpholinylcarbonylmethyl chloride Chloroacetic acid morpholine amide NSC 54542 2-Morpholino-2-oxoethyl chloride MORPHOLINE, 4-(2-CHLOROACETYL)- N-(CHLOROACETYL)MORPHOLINE TIMTEC-BB SBB005580 4-(chloroacetyl)-morpholin chloroaceticacidmorpholide LABOTEST-BB LT00000129 BUTTPARK 30\04-53 AKOS BBS-00000944 4-(2-CHLOROACETYL)MORPHOLINE 4-(CHLOROACETYL)MORPHOLINE 2-CHLORO-1-MORPHOLIN-4-YL-ETHANONE 2-CHLORO-1-MORPHOLINOETHAN-1-ONE 2-CHLORO-1-(4-MORPHOLINYL)-1-ETHANONE 4-(2-Chloroacetyl)morpholine, 97+% Morpholine, 4-(chloroacetyl)- (6CI,7CI,8CI,9CI) Ethanone, 2-chloro-1-(4-morpholinyl)- 2-chloromorpholinoehtan-1-one 2-Chloro-1-morpholin-4-yl-ethanon TIANFU CHEM----4-(2-CHLOROACETYL)MORPHOLINE 2-Chloro-1-(4-morpholinyl)ethanone 1440-61-5 C6H10ClNO2 KETONE ACETYLHALIDE Heterocycles MTS & Sulfhydryl Active Reagents