4-(2-CHLOROACETYL)MORPHOLINE
- CAS No.
- 1440-61-5
- Chemical Name:
- 4-(2-CHLOROACETYL)MORPHOLINE
- Synonyms
- NSC 54542;BUTTPARK 30\04-53;AKOS BBS-00000944;TIMTEC-BB SBB005580;LABOTEST-BB LT00000129;N-(CHLOROACETYL)MORPHOLINE;4-(chloroacetyl)-morpholin;chloroaceticacidmorpholide;4-(CHLOROACETYL)MORPHOLINE;4-(2-CHLOROACETYL)MORPHOLINE
- CBNumber:
- CB6250656
- Molecular Formula:
- C6H10ClNO2
- Molecular Weight:
- 163.6
- MDL Number:
- MFCD00721939
- MOL File:
- 1440-61-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 2-Chloro-1-morpholinoethan-1-one min. 98.0 % | C2588 | 5G | $40 |
| 2-Chloro-1-morpholinoethan-1-one min. 98.0 % | C2588 | 25G | $119 |
| 4-(Chloroacetyl)morpholine | TRC-C363700-1G | 1g | $154 |
| 4-(Chloroacetyl)morpholine | TRC-C363700-10G | 10g | $1185 |
| 4-(2-Chloroacetyl)morpholine >96% | OR1511 | 5g | $21 |
| More product size | |||
| Melting point | 26-30 °C |
|---|---|
| Boiling point | 152-160 °C(Press: 6 Torr) |
| Density | 1.257 g/mL at 25 °C |
| refractive index | n20/D 1.512 |
| Flash point | 110 °C |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | -1.26±0.20(Predicted) |
| form | Solid |
| color | Colourless to Pale Yellow Oil |
| Stability | Hygroscopic |
| CAS DataBase Reference | 1440-61-5(CAS DataBase Reference) |
| EPA Substance Registry System | Morpholine, 4-(chloroacetyl)- (1440-61-5) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H314-H318-H302-H319 | |||||||||
| Precautionary statements | P305+P351+P338-P260h-P301+P330+P331-P303+P361+P353-P405-P501a | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-22 | |||||||||
| Safety Statements | 26-36/37/39 | |||||||||
| RIDADR | UN3261 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29349990 | |||||||||
| NFPA 704 |
|
4-(2-CHLOROACETYL)MORPHOLINE price More Price(49)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | C2588 | 2-Chloro-1-morpholinoethan-1-one min. 98.0 % | 1440-61-5 | 5G | $40 | 2026-04-30 | Buy |
| TCI Chemical | C2588 | 2-Chloro-1-morpholinoethan-1-one min. 98.0 % | 1440-61-5 | 25G | $119 | 2026-04-30 | Buy |
| TRC | TRC-C363700-1G | 4-(Chloroacetyl)morpholine | 1440-61-5 | 1g | $154 | 2026-06-03 | Buy |
| TRC | TRC-C363700-10G | 4-(Chloroacetyl)morpholine | 1440-61-5 | 10g | $1185 | 2026-06-03 | Buy |
| Apolloscientific | OR1511 | 4-(2-Chloroacetyl)morpholine >96% | 1440-61-5 | 5g | $21 | 2026-06-04 | Buy |
4-(2-CHLOROACETYL)MORPHOLINE Chemical Properties,Uses,Production
Chemical Properties
Colorless liquid
Uses
The chloroacetyl derivatives are microbicides for adhesives, cellulose foams, oil emulsions, cooling water, etc.
Synthesis
110-91-8
79-04-9
1440-61-5
Step 1: Morpholine (1.00 mL, 11.5 mmol) and toluene (30 mL) were added to a dry three-necked flask equipped with a magnetic stirrer under nitrogen protection. Potassium carbonate (3.17 g, 22.9 mmol) was then added and stirred until completely dissolved. Chloroacetyl chloride (0.91 mL, 11.4 mmol) was slowly added dropwise under the cooling of an ice bath, and after completion of the dropwise addition, the ice bath was removed, the temperature was raised to 60 °C and the reaction was continuously stirred for 2 hours. After completion of the reaction, the reaction mixture was cooled to room temperature, filtered to remove insoluble solids, and the solids were washed with a small amount of toluene. The filtrate and washings were combined and concentrated under reduced pressure to remove the solvent to give N-chloroacetylmorpholine as a white solid (1.87 g, quantitative yield). The product was characterized by 1H-NMR (270 MHz, CDCl3): δ 3.51-3.54 (m, 2H), 3.62-3.65 (m, 2H), 3.68-3.74 (m, 4H), 4.07 (s, 2H).
References
[1] Patent: EP1650194, 2006, A1. Location in patent: Page/Page column 34
[2] Patent: WO2012/72019, 2012, A1. Location in patent: Page/Page column 71-72
[3] Molecules, 2015, vol. 20, # 11, p. 19984 - 20013
[4] Patent: WO2016/147144, 2016, A1. Location in patent: Page/Page column 222
[5] Journal of Medicinal Chemistry, 2009, vol. 52, # 21, p. 6660 - 6671
4-(2-CHLOROACETYL)MORPHOLINE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21531 | 55 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8491 | 58 |
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88298848 | info@edengenechem.com | China | 2163 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29780 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21135 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30203 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34526 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14301 | 58 |
View Lastest Price from 4-(2-CHLOROACETYL)MORPHOLINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-09 | 4-(2-CHLOROACETYL)MORPHOLINE
1440-61-5
|
$1.00 | 1KG | 99% | 200kg | Career Henan Chemical Co |
-
- 4-(2-CHLOROACETYL)MORPHOLINE
1440-61-5
- $1.00
- 99%
- Career Henan Chemical Co
