Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>(S)-2-((Methoxycarbonyl)aMino)-3-Methylbutanoic acid

(S)-2-((Methoxycarbonyl)aMino)-3-Methylbutanoic acid

(S)-2-((Methoxycarbonyl)aMino)-3-Methylbutanoic acid Structure
(S)-2-((Methoxycarbonyl)aMino)-3-Methylbutanoic acid structure
CAS No.
74761-42-5
Chemical Name:
(S)-2-((Methoxycarbonyl)aMino)-3-Methylbutanoic acid
Synonyms
(methoxycarbonyl)-L-valine;N-(Methoxycarbonyl)-L-valine;MOC-L-Valine;N-(methoxycarbonyl)-Valine;MOC-L;MOC-Val;MOC-L-Val;Moc-Val-OH;Moc-L-Val-OH;N-Moc-L-valine
CBNumber:
CB62593005
Molecular Formula:
C7H13NO4
Molecular Weight:
175.18
MDL Number:
MFCD12795357
MOL File:
74761-42-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 04:13:32
Request For Quotation

(S)-2-((Methoxycarbonyl)aMino)-3-Methylbutanoic acid Properties

Melting point 109.0 to 113.0 °C
Boiling point 315.9±25.0 °C(Predicted)
Density 1.154±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
form powder to crystal
pka 4.44±0.10(Predicted)
color White to Almost white
optical activity Consistent with structure
InChI InChI=1S/C7H13NO4/c1-4(2)5(6(9)10)8-7(11)12-3/h4-5H,1-3H3,(H,8,11)(H,9,10)/t5-/m0/s1
InChIKey CEFVHPDFGLDQKU-YFKPBYRVSA-N
SMILES C(O)(=O)[C@H](C(C)C)NC(OC)=O

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
HS Code  2924297099
REACH Registrations Active

(S)-2-((Methoxycarbonyl)aMino)-3-Methylbutanoic acid price More Price(50)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical M2857 N-(Methoxycarbonyl)-L-valine >98.0%(HPLC)(T) 74761-42-5 5g $35 2026-04-30 Buy
TCI Chemical M2857 N-(Methoxycarbonyl)-L-valine >98.0%(HPLC)(T) 74761-42-5 25g $60 2026-04-30 Buy
Usbiological 283164 S-2-((Methoxycarbonyl)amino)-3-methylbutanoic acid Asreported 74761-42-5 50g $333 2026-06-03 Buy
Usbiological 283164 S-2-((Methoxycarbonyl)amino)-3-methylbutanoic acid Asreported 74761-42-5 100g $460 2026-06-03 Buy
Usbiological 283164 S-2-((Methoxycarbonyl)amino)-3-methylbutanoic acid Asreported 74761-42-5 250g $672 2026-06-03 Buy
Product number Packaging Price Buy
M2857 5g $35 Buy
M2857 25g $60 Buy
283164 50g $333 Buy
283164 100g $460 Buy
283164 250g $672 Buy

(S)-2-((Methoxycarbonyl)aMino)-3-Methylbutanoic acid Chemical Properties, Uses, Production

Uses

(S)-2-((Methoxycarbonyl)aMino)-3-Methylbutanoic acid can be used as Ledipasvir Intermediate, mainly used in laboratory R&D process and chemical production process.

Synthesis

1.png
Na2CO3 (1.83 g, 17.2 mmol) was added to an aq solution of NaOH (33 mL of 1 M/H2O, 33 mmol) and L-valine (3.900 g, 33.29 mmol) and the resulting solution was cooled with ice-water bath. Methyl chloroformate (2.8 mL, 36.1 mmol) was added dropwise, the cooling bath was removed and the reaction mixture was stirred at ambient temperature for 3.25 h. The reaction mixture was washed with ether (3x17 mL), and the aqueous phase was cooled with ice-water bath and acidified with conc HCl to a pH of 1-2, and extracted with CH2Cl2 (3x17 mL). The organic phase was dried (anhyd MgSO4), filtered, and concentrated in vacuo. Cap-1 as a white solid (5.00 g, 86%).

References

[1] Patent: WO2013/123092, 2013, A1. Location in patent: Paragraph 0111

(S)-2-((Methoxycarbonyl)aMino)-3-Methylbutanoic acid Preparation Products And Raw materials

Raw materials

L-Valine hydrochloride L-Valine S-1-Pyrrolidinecarboxylic acid, 2-(6-bromo-1H-benzimidazol-2-yl)-, 1,1-dimethyleth Methyl chloroformate Water
Sodium carbonate 2-Methyltetrahydrofuran Sodium hydroxide

1of2

Preparation Products

(S)-2-((Methoxycarbonyl)aMino)-3-Methylbutanoic acid Suppliers

Global Suppliers ( 352)
Supplier Tel Email Country ProdList Advantage
Ark Pharm, Inc. 847-367-3680 sales@arkpharminc.com United States 1669 56
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
GL Biochem (Shanghai) Ltd 21-61263452 13641803416 ymbetter@glbiochem.com China 9981 64
JinYan Chemicals(ShangHai) Co.,Ltd. 13817811078 sales@jingyan-chemical.com China 9963 60
Jia Xing Isenchem Co.,Ltd 0573-85285100 18627885956 isenchem@163.com China 9389 66
Shanghai Chiral Chemicals Inc. 021-37285021 13472570865 tym7xi@aliyun.com China 299 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Synches Co., Ltd. 021-53292253 biz@synches.com China 199 64
Changzhou Joyous Chemical Co., Ltd. 0519-85607258 sales@joyouschem.com China 292 60
Supplier Advantage
Ark Pharm, Inc. 56
Energy Chemical 61
GL Biochem (Shanghai) Ltd 64
JinYan Chemicals(ShangHai) Co.,Ltd. 60
Jia Xing Isenchem Co.,Ltd 66
Shanghai Chiral Chemicals Inc. 64
Shanghai Hanhong Scientific Co.,Ltd. 64
Shandong Xiya Chemical Co., Ltd 57
Synches Co., Ltd. 64
Changzhou Joyous Chemical Co., Ltd. 60

View Latest Price from (S)-2-((Methoxycarbonyl)aMino)-3-Methylbutanoic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
MOC-L-Valine pictures 2026-09-11 MOC-L-Valine
74761-42-5
 1KG 98.5%min 10 tons WUHAN FORTUNA CHEMICAL CO., LTD
(S)-2-((Methoxycarbonyl)aMino)-3-Methylbutanoic acid pictures 2026-03-20 (S)-2-((Methoxycarbonyl)aMino)-3-Methylbutanoic acid
74761-42-5
 $10.00 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
(S)-2-((Methoxycarbonyl)aMino)-3-Methylbutanoic acid pictures 2025-04-04 (S)-2-((Methoxycarbonyl)aMino)-3-Methylbutanoic acid
74761-42-5
 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
  • MOC-L-Valine pictures
  • MOC-L-Valine
    74761-42-5
  • $0.00
  • 98.5%min
  • WUHAN FORTUNA CHEMICAL CO., LTD

(S)-2-((Methoxycarbonyl)aMino)-3-Methylbutanoic acid Spectrum

(S)-2-((Methoxycarbonyl)aMino)-3-Methylbutanoic acid(74761-42-5)1HNMR

74761-42-5 ((S)-2-((Methoxycarbonyl)aMino)-3-Methylbutanoic acid) Related Search:

Ledipasvir (S)-5-Boc-5-azaspiro[2.4]heptane-6-carboxylic acid Moc-Leu-OH (2R)-1-methoxycarbonylpyrrolidine-2-carboxylic acid Moc-Ile-OH
Moc-Val-Val-OH 1,2-Pyrrolidinedicarboxylicacid,1-methylester,(2S)-(9CI) MOC-D-Valine Methoxycarbonyl-L-tert-leucine Benzeneacetic acid, a-[(Methoxycarbonyl)aMino]-, (S)-
(R)-2-(methoxycarbonylamino)-2-phenylacetic acid ledipasvir interMediate tert-Butyl 6-(5-(7-bromo-9,9-difluoro-9H-fluoren-2-yl) 2,7-DibroMo-9,9-difluoro-9H-fluorene (S)-2-((Methoxycarbonyl)aMino)-3-Methylbutanoic acid
2-Azabicyclo[2.2.1]heptane-2-carboxylic acid, 3-(6-broMo-1H-benziMidazol-2-yl)-, 1,1-diMethylethyl ester,(1R,3S,4S)- 1-(7-broMo-9,9-difluoro-9H-fluoren-2-yl)-2-chloro-Ethanone ledipasvir interMediate

1of4

(S)-2-((Methoxycarbonyl)aMino)-3-Methylbutanoic acid Methoxycarbonyl valine (Synonyms:N-(methoxycarbonyl)-L-Valine) L-Valine, N-(Methoxycarbonyl)- Moc-Val-OH (2S)-2-[(Methoxycarbonyl)aMino]-3-Methylbutanoic acid MOC-L-Val MOC-Val Moc-L-Val-OH N-(Methoxycarbonyl)-L-valine (S)-2-((Methoxycarbonyl)amino)-3-methylbutanoic 2-Methoxycarbonylamino-3-methyl-butyric acid (S)-2-[(Methoxycarbonyl)amino]-3-methylbutyric Acid MOC-L (S)-2-((Methoxycarbonyl)amino)-3-methylbutanoicaci (S)-2-((Methoxycarbonyl)aMino)-3-Methylbutanoic acid USP/EP/BP (S)-2-((Methoxycarbonyl)amino)-4-methylbutanoic Acid (S)-2-((Methoxycarbonyl)aMino)-3-MethylbutaChemicalbooknoicacid Moc-L-Valine (N-(Methoxycarbonyl)-L-Valine) (S)-2-((Methoxycarbonyl)amino)-3-methylbutanoic acidQ: What is (S)-2-((Methoxycarbonyl)amino)-3-methylbutanoic acid Q: What is the CAS Number of (S)-2-((Methoxycarbonyl)amino)-3-methylbutanoic acid Q: What is the storage condition of (S)-2-((Methoxycarbonyl)amino)-3-methylbutanoic acid Q: What are the applications of (S)-2-((Methoxycarbonyl)amino)-3-methylbutanoic acid Moc-L-Valine-OH Oliceridine Impurity 8 N-Moc-L-valine MOC-L-Valine (methoxycarbonyl)-L-valine N-(methoxycarbonyl)-Valine N-(Methoxycarbonyl)-L-valine 74761-42-5 6885-20-8 4761-42-5 74761-47-5 Pharmaceuticalintermediates