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Succinimido (S)-2-[(tert-butoxycarbonyl)amino]propionate

Succinimido (S)-2-[(tert-butoxycarbonyl)amino]propionate structure

CAS No.: 3392-05-0

Chemical Name:: Succinimido (S)-2-[(tert-butoxycarbonyl)amino]propionate

Synonyms: Boc-Ala-OSu;BOC-L-ALA-OSU;BOC-D-ALA-OSU;Boc-Ala-OSu, BR;BOC-D-ALANINE-OSU;BOC-L-Alanine-Osu;BOC-ALA-OSU CAS:3392-05-0;(Tert-Butoxy)Carbonyl Ala-OSu;N-Boc-L-alanine N-succinimidyl;Boc-L-Alanine N-hydroxysuccinimde

CBNumber:: CB6277666

Molecular Formula:: C12H18N2O6

Molecular Weight:: 286.28

MDL Number:: MFCD00065974

MOL File:: 3392-05-0.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-24 14:59:07

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Succinimido (S)-2-[(tert-butoxycarbonyl)amino]propionate Properties

Melting point	161-163 °C
alpha	-52 º (c=2.5% in dioxane)
Density	1.27±0.1 g/cm3(Predicted)
storage temp.	-20°C
solubility	Soluble in water or 1% acetic acid
form	Powder
pka	10.81±0.46(Predicted)
Appearance	White to off-white Solid
optical activity	[α]20/D 52±3.5°, c = 2.5% in dioxane
Sensitive	Moisture Sensitive
BRN	3560476
Major Application	peptide synthesis
InChI	1S/C12H18N2O6/c1-7(13-11(18)19-12(2,3)4)10(17)20-14-8(15)5-6-9(14)16/h7H,5-6H2,1-4H3,(H,13,18)/t7-/m0/s1
InChIKey	COMUWNFVTWKSDT-ZETCQYMHSA-N
SMILES	C[C@H](NC(=O)OC(C)(C)C)C(=O)ON1C(=O)CCC1=O
CAS DataBase Reference	3392-05-0(CAS DataBase Reference)
UNSPSC Code	12352202
NACRES	NA.22

SAFETY

Risk and Safety Statements

PPE

Eyeshields, Gloves, type N95 (US)

Safety Statements

22-24/25

WGK Germany

3-10-21

HS Code

29224999

Storage Class

11 - Combustible Solids

NFPA 704

	1
0		0

Succinimido (S)-2-[(tert-butoxycarbonyl)amino]propionate price More Price(54)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	15385	Boc-Ala-OSu	3392-05-0	5g	$113	2023-06-20	Buy
TCI Chemical	B3413	Boc-Ala-OSu	3392-05-0	5G	$63	2026-04-30	Buy
TCI Chemical	B3413	Boc-Ala-OSu	3392-05-0	25G	$190	2026-04-30	Buy
Usbiological	236334	Boc-L-alanine N-hydroxysuccinimide ester 98+% (HPLC) ≥98%(HPLC)		5g	$163	2026-06-03	Buy
Usbiological	236334	Boc-L-alanine N-hydroxysuccinimide ester 98+% (HPLC) ≥98%(HPLC)		25g	$199	2026-06-03	Buy

Product number	Packaging	Price	Buy
15385	5g	$113	Buy
B3413	5G	$63	Buy
B3413	25G	$190	Buy
236334	5g	$163	Buy
236334	25g	$199	Buy

Succinimido (S)-2-[(tert-butoxycarbonyl)amino]propionate Chemical Properties, Uses, Production

Chemical Properties

White powder

Uses

Reactant involved in synthesis of:

Muramyldipeptide analogs via solid-phase synthesis
Microcin C analogs for use as antibacterials
Lipid I and nucleoside diphosphate peptide derivatives via N-methylimidazolium chloride catalyzed coupling
N-Protected dipeptide acids
Free and peptide-bound glycated amino acids for studies of interactions with human Caco-2 interstinal epithelial cell apical membrane transport proteins
7-Substituted camptothecin conjugates with RGD-peptides as avβ3 integrin ligands

reaction suitability

reaction type: Boc solid-phase peptide synthesis

Synthesis

15761-38-3

N-(1,2,2,2-TETRACHLOROETHOXYCARBONYLOXY)SUCCINIMIDE

107960-02-1

Succinimido (S)-2-[(tert-butoxycarbonyl)amino]propionate

3392-05-0

Example 11: Preparation of N-succinimidyl N-tert-butoxycarbonyl-L-alanine ester 0.95 g (5 mmol) of N-tert-butoxycarbonyl-L-alanine and 0.66 ml (5.5 mmol) of N-methylmorpholine were dissolved in 6 ml of tetrahydrofuran (THF), followed by a one-time addition of 1.8 g (5.5 mmol) of N-succinimidyl 1,2,2,2-tetrachloroethyl carbonate. The reaction mixture was stirred at 20°C for 2 hours. After completion of the reaction, it was diluted by adding about 25 ml of ethyl acetate, and the organic phase was washed quickly with 1N HCl solution, potassium bicarbonate solution in sequence, and finally washed twice with water. The organic phase was dried over anhydrous magnesium sulfate and concentrated under reduced pressure. The residue was recrystallized by ethyl acetate/petroleum ether mixed solvent to give 1.25 g (87% yield) of white crystals. Evaporation of the mother liquor and recrystallization recovered 0.1 g of product, raising the overall yield to 94%. The melting point of the product was 158 °C. [α]D20 = +50.7 (c = 2, dioxane).

References

[1] Journal of Organic Chemistry, 1987, vol. 52, # 12, p. 2364 - 2367
[2] Patent: US4782164, 1988, A

Succinimido (S)-2-[(tert-butoxycarbonyl)amino]propionate Preparation Products And Raw materials

Raw materials

N-(tert-Butoxycarbonyl)-L-alanine N-(1,2,2,2-Tetrachloroethoxycarbonyloxy)succinimide PETROLEUM ETHER Ethyl acetate 4-Methylmorpholine

Tetrahydrofuran

1of2

Preparation Products

Succinimido (S)-2-[(tert-butoxycarbonyl)amino]propionate Suppliers

Global Suppliers ( 229)

Supplier	Tel	Email	Country	ProdList	Advantage
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
GL Biochem (Shanghai) Ltd	21-61263452 13641803416	ymbetter@glbiochem.com	China	9981	64
Capot Chemical Co., Ltd	+86 (0) 571 85 58 67 18		China	18187	66
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.	+86-21-54098501	sales@sinch.com.cn	China	11592	64
Jia Xing Isenchem Co.,Ltd	0573-85285100 18627885956	isenchem@163.com	China	9389	66
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64
Chemsky (shanghai) International Co.,Ltd	021-50135380	shchemsky@sina.com	China	15350	60

Supplier	Advantage
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
Alfa Aesar	84
Energy Chemical	61
GL Biochem (Shanghai) Ltd	64
Capot Chemical Co., Ltd	66
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.	64
Jia Xing Isenchem Co.,Ltd	66
Shanghai Hanhong Scientific Co.,Ltd.	64
Chemsky (shanghai) International Co.,Ltd	60

View Latest Price from Succinimido (S)-2-[(tert-butoxycarbonyl)amino]propionate manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-17	Boc-L-Ala-OSu 3392-05-0		1kg	95%	1T+	Sichuan HongRi Pharma-Tech Co.,Ltd
2026-08-08	Succinimido (S)-2-[(tert-butoxycarbonyl)amino]propionate 3392-05-0		1g	98%	100kg	Hangzhou ICH Biofarm Co., Ltd
2021-07-13	Succinimido (S)-2-[(tert-butoxycarbonyl)amino]propionate 3392-05-0	$10.00-15.00	1KG	99%+ HPLC		Zhuozhou Wenxi import and Export Co., Ltd

Boc-L-Ala-OSu
3392-05-0
95%
Sichuan HongRi Pharma-Tech Co.,Ltd

Succinimido (S)-2-[(tert-butoxycarbonyl)amino]propionate
3392-05-0
98%
Hangzhou ICH Biofarm Co., Ltd

Succinimido (S)-2-[(tert-butoxycarbonyl)amino]propionate
3392-05-0
$10.00-15.00
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

Succinimido (S)-2-[(tert-butoxycarbonyl)amino]propionate Spectrum

Succinimido (S)-2-[(tert-butoxycarbonyl)amino]propionate(3392-05-0)¹HNMR

3392-05-0 (Succinimido (S)-2-[(tert-butoxycarbonyl)amino]propionate) Related Search:

Boc-4-iodo-L-phenylalanine Boc-D-2,4-diaminobutyric acid Boc-L-2,4-diaminobutyric acid Boc-D-aspartic acid 4-benzyl ester Boc-L-glutamic acid 5-cyclohexyl ester

Boc-6-AMinocaproic acid Boc-L-aspartic acid 4-tert-butyl ester N-tert-Butoxycarbonyl-L-glutamic acid gamma-tert-butyl ester Boc-N-beta-Trityl-L-asparagine Boc-Oic-OH

Boc-Sar-OH Boc-Glu(OFm)-OH Boc-Orn-OH Boc-Phe-Ser-Arg-AMC acetate salt Boc-Nle-OH dcha

Boc-Trp-OSu Boc-Leu-OSu Boc-Met-OSu

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BOC-D-ALA-OSU BOC-D-ALANINE-OSU BOC-D-ALANINE N-HYDROXYSUCCINIMIDE ESTER BOC-D-ALANINE-HYDROXYSUCCINIMIDE ESTER N-ALPHA-T-BOC-D-ALANINE N-HYDROXYSUCCINIMIDE ESTER succinimido (S)-2-[(tert-butoxycarbonyl)amino]propionate Boc-L-Alanine N-hydroxysuccinimde ester BOC-L-ALA-OSU Boc-L-alanineydroxysuccinimidester Boc-L-alanine N-succinimidyl ester BOC-ALANINE-1-HYDROXYSUCCINIMIDE ESTER BOC-L-ALANINE-HYDROXYSUCCINIMIDESTER N-(tert-butoxycarbonyl)-L-alanine hydroxysuccinimide ester Boc-L-alanine N-succinimidyl ester, Boc-L-alanine hydroxysuccinimide ester (S)-2-[[(1,1-Dimethylethoxy)carbonyl]amino]propionic acid 2,5-dioxopyrrolidin-1-yl ester [(S)-1-[[(2,5-Dioxo-1-pyrrolidinyl)oxy]carbonyl]ethyl]carbamic acid 1,1-dimethylethyl ester N-(tert-Butoxycarbonyl)alanine 2,5-dioxopyrrolizino N-(tert-Butoxycarbonyl)-L-alanine 2,5-dioxopyrrolizino N-(tert-Butyloxycarbonyl)-L-alanine 2,5-dioxopyrrolizino N-(tert-Butyloxycarbonyl)-L-alanine succinimidyl ester (2,5-dioxopyrrolidin-1-yl) 2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate 2-(tert-butoxycarbonylamino)propionic acid succinimido ester Succinimido-2-[(tert-butoxycarbonyl)amino]propionate Boc-L-Alanine N-hydroxysuccinimde Boc-L-alanineN-hydroxysuccinimide ester≥ 98% (HPLC) 2,5-dioxopyrrolidin-1-yl (2S)-2-{[(tert-butoxy)carbonyl]aMino}propanoate N-Boc-L-alanine N-succiniMidyl ester, 98% 2,5-dioxopyrrolidin-1-yl 2-{[(tert-butoxy)carbonyl]aMino}propanoate (Tert-Butoxy)Carbonyl Ala-OSu (S)-2,5-Dioxopyrrolidin-1-yl2-((tert-butoxycarbonyl)amino)propanoate Boc-Ala-OSu, BR N-t-Butoxycarbonyl-L-alanine N-Hydroxysuccinimide Ester L-Alanine, N-[(1,1-dimethylethoxy)carbonyl]-, 2,5-dioxo-1-pyrrolidinyl ester BOC-ALA-OSU CAS:3392-05-0 Succinimido (S)-2-[(tert-butoxycarbonyl)amino]propionate USP/EP/BP BOC-L-Alanine-Osu Boc-L- alanine N- succinimide ester N-Boc-L-alanine N-succinimidyl Boc-Ala-OSu 3392-05-0 C12H18N2O6 Specialty Synthesis Peptide Synthesis Amino Acid Derivatives Alanine Alanine [Ala, A] Boc-Amino Acids and Derivative Boc-Amino acid series Amino Acid Derivatives Amino Acids