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5-Bromo-4,6-dichloropyrimidin-2-amine

CAS No.
7781-26-2
Chemical Name:
5-Bromo-4,6-dichloropyrimidin-2-amine
Synonyms
5-Bromo-4,6-dichloropyrimidin-2-amine;2-Amino-5-bromo-4,6-dichloropyrimidine;2-Pyrimidinamine, 5-bromo-4,6-dichloro-;5-Bromo-4,6-dichloro-pyrimidin-2-ylamine;2-Amino-5-bromo-4,6-dichloropyrimidine97%;2-Amino-5-bromo-4,6-dichloropyrimidine 97%;5-Bromo-4,6-dichloropyrimidin-2-amine, 2-Amino-5-bromo-4,6-dichloro-1,3-diazine
CBNumber:
CB3743294
Molecular Formula:
C4H2BrCl2N3
Molecular Weight:
242.89
MDL Number:
MFCD00275455
MOL File:
7781-26-2.mol
MSDS File:
SDS
Last updated:2026-09-12 18:52:11

5-Bromo-4,6-dichloropyrimidin-2-amine Properties

Boiling point 419.4±55.0 °C(Predicted)
Density 2.054±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka -1.47±0.10(Predicted)
Appearance White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P271-P261-P280
Hazard Codes  Xi
HS Code  2933599590

5-Bromo-4,6-dichloropyrimidin-2-amine price More Price(45)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR2987 2-Amino-5-bromo-4,6-dichloropyrimidine 95% 7781-26-2 100mg $35 2026-06-04 Buy
Apolloscientific OR2987 2-Amino-5-bromo-4,6-dichloropyrimidine 95% 7781-26-2 250mg $45 2026-06-04 Buy
Apolloscientific OR2987 2-Amino-5-bromo-4,6-dichloropyrimidine 95% 7781-26-2 500mg $67 2026-06-04 Buy
Apolloscientific OR2987 2-Amino-5-bromo-4,6-dichloropyrimidine 95% 7781-26-2 1g $100 2026-06-04 Buy
Apolloscientific OR2987 2-Amino-5-bromo-4,6-dichloropyrimidine 95% 7781-26-2 5g $387 2026-06-04 Buy
Product number Packaging Price Buy
OR2987 100mg $35 Buy
OR2987 250mg $45 Buy
OR2987 500mg $67 Buy
OR2987 1g $100 Buy
OR2987 5g $387 Buy

5-Bromo-4,6-dichloropyrimidin-2-amine Chemical Properties,Uses,Production

Synthesis

2-Amino-4,6-dichloropyrimidine

56-05-3

5-BROMO-4,6-DICHLOROPYRIMIDIN-2-AMINE

7781-26-2

The general procedure for the synthesis of 5-bromo-4,6-dichloropyrimidin-2-amine from 2-amino-4,6-dichloropyrimidine was as follows: over a period of 20 min, bromine (0.85 mL, 0.0166 mol) was slowly added dropwise to a stirring 1:1 mixture of 2-amino-4,6-dichloropyrimidine (CAS # 56-05-3, 1.70 g, 0.01037 mol) and sodium carbonate ( 1.00 g, 0.01244 mol) in a 1:1 methanol/water (30 mL) mixture and the reaction was carried out at room temperature. Ten minutes after completion of the dropwise addition, additional sodium carbonate (0.78 g, 0.0093 mol) was added to the reaction mixture. The reaction mixture was continued to be stirred at room temperature for 42 hours. Upon completion of the reaction, the reaction mixture was diluted with aqueous sodium bicarbonate to precipitate 5-bromo-4,6-dichloropyrimidin-2-amine precipitate which was collected by filtration and washed with distilled water. Vacuum drying gave 2.11 g of white solid in 83.7% yield. The product was characterized by 1H NMR (300 MHz, d6-DMSO): δ 7.67 (s, 1H), 7.70 (s, 1H). Mass spectrum (DC1-NH3) showed: m/z = 241 (M + H)+, m/z = 258 (M + NH4)+.

References

[1] Patent: US2004/204386, 2004, A1
[2] Patent: US2010/331294, 2010, A1. Location in patent: Page/Page column 18
[3] Yakugaku Zasshi, 1942, vol. 62, p. 315,333; dtsch. Ref. S. 95, 106
[4] Chem.Abstr., 1951, p. 5150

5-Bromo-4,6-dichloropyrimidin-2-amine Preparation Products And Raw materials

Raw materials

Preparation Products

5-Bromo-4,6-dichloropyrimidin-2-amine Suppliers

Global( 60)Suppliers
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Shanghai Longsheng chemical Co.,Ltd. 58099637 13585536065 sales@shlschem.com China 9880 59
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Shanghai Ennopharm Co., Ltd. +86 (21) 6435-5022 China 4263 65
Shanghai Jian Chao Chemical Technology Co., Ltd. 150-2103-5486 18017383231 983544897@qq.com China 9336 55
SynAsst Chemical. 021-60343070 China 12731 55
ShangHai AmK Pharmaceutical Technology Co., Ltd. 微信 18019252918 18019252918 sale@amkchem.com China 14982 55
Shanghai Kahn Pharmaceutical Co., Ltd. 021-34979681; 17701870669 41513101@qq.com China 1785 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60

View Lastest Price from 5-Bromo-4,6-dichloropyrimidin-2-amine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
	5-BROMO-4,6-DICHLOROPYRIMIDIN-2-AMINE pictures 2025-12-24 5-BROMO-4,6-DICHLOROPYRIMIDIN-2-AMINE
7781-26-2
1KG 99.0% 1000 tons Shaanxi Dideu Medichem Co. Ltd
5-Bromo-4,6-dichloro-pyrimidin-2-ylamine 2-Amino-5-bromo-4,6-dichloropyrimidine97% 5-Bromo-4,6-dichloropyrimidin-2-amine, 2-Amino-5-bromo-4,6-dichloro-1,3-diazine 2-Amino-5-bromo-4,6-dichloropyrimidine 2-Amino-5-bromo-4,6-dichloropyrimidine 97% 2-Pyrimidinamine, 5-bromo-4,6-dichloro- 5-Bromo-4,6-dichloropyrimidin-2-amine 7781-26-2 C4H2BrCl2N3 Halides Pyrazines, Pyrimidines & Pyridazines Pyrazines, Pyrimidines & Pyridazines