Methacetin
- CAS No.
- 51-66-1
- Chemical Name:
- Methacetin
- Synonyms
- N-(4-METHOXYPHENYL)ACETAMIDE;p-acetaniside;4-Methoxy acetanlide;Metacetin;METHACETIN;acetaniside;4-Acetaniside;AURORA KA-3672;MethacetinN-(4-;p-Acetanasidine
- CBNumber:
- CB6310310
- Molecular Formula:
- C9H11NO2
- Molecular Weight:
- 165.19
- MDL Number:
- MFCD00014963
- MOL File:
- 51-66-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 128-130 °C(lit.) |
|---|---|
| Boiling point | 293.03°C (rough estimate) |
| Density | 1.1603 (rough estimate) |
| refractive index | 1.5839 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Crystalline |
| pka | 14.53±0.70(Predicted) |
| color | White |
| Water Solubility | 0.42 g/100 mL (20 ºC) |
| Merck | 14,51 |
| BRN | 387887 |
| Stability | Hygroscopic |
| CAS DataBase Reference | 51-66-1(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 13E468TFHP |
| NIST Chemistry Reference | N-(4-Methoxyphenyl)acetic acid amide(51-66-1) |
| EPA Substance Registry System | Acetamide, N-(4-methoxyphenyl)- (51-66-1) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312+P330-P501-P301+P312a-P330-P501a | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-36/38 | |||||||||
| Safety Statements | 36-37/39-26 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | AE8290000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29242990 | |||||||||
| Toxicity | LD50 orl-mus: 1190 mg/kg TXAPA9 19,20,71 | |||||||||
| NFPA 704 |
|
Methacetin price More Price(42)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | A0019 | p-Acetanisidide >98.0%(HPLC)(N) | 51-66-1 | 25g | $90 | 2026-04-30 | Buy |
| TCI Chemical | A0019 | p-Acetanisidide >98.0%(HPLC)(N) | 51-66-1 | 100g | $220 | 2026-04-30 | Buy |
| TRC | TRC-M258770-500MG | Methacetin | 51-66-1 | 500mg | $115 | 2026-06-03 | Buy |
| TRC | TRC-M258770-1G | Methacetin | 51-66-1 | 1g | $199 | 2026-06-03 | Buy |
| Usbiological | 016096 | Methacetin | 51-66-1 | 1g | $418 | 2026-06-03 | Buy |
Methacetin Chemical Properties,Uses,Production
Chemical Properties
LIGHT BEIGE CRYSTALLINE POWDER
Uses
Methacetin is evaluated in a breath test to predict early liver disfunction due to valproic acid and other cause. Methacetin breath test (MBT) is a rapid, non-invasive assessment of liver function in acute severe liver disease and a potential key tool in future dignosis.
Definition
ChEBI: Methacetin is a member of the class of acetamides that is paracetamol in which the hydrogen of phenolic hydroxy group has been replaced by a methyl group. It is a member of acetamides and an aromatic ether. It is functionally related to a p-anisidine and a paracetamol.
Synthesis Reference(s)
Journal of the American Chemical Society, 89, p. 7131, 1967 DOI: 10.1021/ja01002a061
The Journal of Organic Chemistry, 42, p. 3755, 1977
Organic Syntheses, Coll. Vol. 3, p. 661, 1955
Safety Profile
Moderately toxic by ingestion andother unspecified routes. When heated to decomposition itemits toxic fumes of NOx.
Methacetin Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Ark Pharm, Inc. | 847-367-3680 | sales@arkpharminc.com | United States | 1669 | 56 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Shanghai Longsheng chemical Co.,Ltd. | 58099637 13585536065 | sales@shlschem.com | China | 9880 | 59 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
View Lastest Price from Methacetin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-28 | Methacetin
51-66-1
|
$10.00-30.00 | 10kg | 99% | 100000kg | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2019-07-14 | Methacetin
51-66-1
|
$1.00 | 1KG | 99% | 100kg | Career Henan Chemical Co |
-
- Methacetin
51-66-1
- $10.00-30.00
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
-
- Methacetin
51-66-1
- $1.00
- 99%
- Career Henan Chemical Co
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