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Methacetin

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Company Name: J & K SCIENTIFIC LTD.  
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Methacetin manufacturers

  • Methacetin
  • Methacetin pictures
  • $30.00
  • 2026-05-28
  • CAS:51-66-1
  • Min. Order: 10kg
  • Purity: 99%
  • Supply Ability: 100000kg
  • Methacetin
  • Methacetin pictures
  • $1.00
  • 2019-07-14
  • CAS:51-66-1
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 100kg
Methacetin Basic information
Product Name:Methacetin
Synonyms:p-Acetanasidine~N-(Methoxyphenyl)acetamide;p-Acetanasidine;p-Acetoanisidide;4'-Methoxyacetanilide, 99+%;n-(methoxyphenyl)acetamide;acetaniside;p-acetylanisidine;PARA-ACETANISIDIDE
CAS:51-66-1
MF:C9H11NO2
MW:165.19
EINECS:200-114-2
Product Categories:Intermediates of Dyes and Pigments;Anilines, Amides & Amines;Anisoles, Alkyloxy Compounds & Phenylacetates;Aromatics;Diagnostic
Mol File:51-66-1.mol
Methacetin Structure
Methacetin Chemical Properties
Melting point 128-130 °C(lit.)
Boiling point 293.03°C (rough estimate)
density 1.1603 (rough estimate)
refractive index 1.5839 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Methanol (Slightly)
form Crystalline
pka14.53±0.70(Predicted)
color White
Water Solubility 0.42 g/100 mL (20 ºC)
Merck 14,51
BRN 387887
Stability:Hygroscopic
CAS DataBase Reference51-66-1(CAS DataBase Reference)
NIST Chemistry ReferenceN-(4-Methoxyphenyl)acetic acid amide(51-66-1)
EPA Substance Registry SystemAcetamide, N-(4-methoxyphenyl)- (51-66-1)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 22-36/38
Safety Statements 36-37/39-26
WGK Germany 1
RTECS AE8290000
TSCA TSCA listed
HS Code 29242990
ToxicityLD50 orl-mus: 1190 mg/kg TXAPA9 19,20,71
MSDS Information
ProviderLanguage
N-(4-Methoxyphenyl)acetamide English
ACROS English
SigmaAldrich English
ALFA English
Methacetin Usage And Synthesis
Chemical PropertiesLIGHT BEIGE CRYSTALLINE POWDER
UsesMethacetin is evaluated in a breath test to predict early liver disfunction due to valproic acid and other cause. Methacetin breath test (MBT) is a rapid, non-invasive assessment of liver function in acute severe liver disease and a potential key tool in future dignosis.
DefinitionChEBI: Methacetin is a member of the class of acetamides that is paracetamol in which the hydrogen of phenolic hydroxy group has been replaced by a methyl group. It is a member of acetamides and an aromatic ether. It is functionally related to a p-anisidine and a paracetamol.
Synthesis Reference(s)Journal of the American Chemical Society, 89, p. 7131, 1967 DOI: 10.1021/ja01002a061
The Journal of Organic Chemistry, 42, p. 3755, 1977
Organic Syntheses, Coll. Vol. 3, p. 661, 1955
Safety ProfileModerately toxic by ingestion andother unspecified routes. When heated to decomposition itemits toxic fumes of NOx.
Tag:Methacetin(51-66-1) Related Product Information
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