Bicinchoninic Acid Disodium Salt
- CAS No.
- 979-88-4
- Chemical Name:
- Bicinchoninic Acid Disodium Salt
- Synonyms
- BCA;BICINCHONINIC ACID DISODIUM SALT HYDRATE;BCA-2Na;Bicinchonic acid;SodiumBicinchoniate;BCA Disodium;BCA DISODIUM SALT;SodiumBicinchoninate;Bicinchoninic acid h;Disodium bicinchoninate
- CBNumber:
- CB6316211
- Molecular Formula:
- C20H13N2NaO4
- Molecular Weight:
- 368.32
- MDL Number:
- MFCD00037500
- MOL File:
- 979-88-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 300℃ |
|---|---|
| storage temp. | Inert atmosphere,2-8°C |
| solubility | 0.5% sodium bicarbonate: soluble50mg/mL |
| form | Powder/Chunks |
| color | white to light yellow |
| Water Solubility | Soluble in water. |
| Stability | Hygrscopic |
| Major Application |
diagnostic assay manufacturing hematology histology |
| InChI | InChI=1S/C20H12N2O4.Na.H/c23-19(24)13-9-17(21-15-7-3-1-5-11(13)15)18-10-14(20(25)26)12-6-2-4-8-16(12)22-18;;/h1-10H,(H,23,24)(H,25,26);; |
| InChIKey | AUPXFICLXPLHBB-UHFFFAOYSA-L |
| SMILES | C(C1=CC(C2=NC3=CC=CC=C3C(C(=O)O)=C2)=NC2=CC=CC=C12)(=O)O.[NaH] |
| CAS DataBase Reference | 979-88-4(CAS DataBase Reference) |
| EPA Substance Registry System | [2,2'-Biquinoline]-4,4'-dicarboxylic acid, disodium salt (979-88-4) |
| UNSPSC Code | 12171500 |
| NACRES | NA.47 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313 | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 36/37-42-36/38-36/37/38-20/21/22 | |||||||||
| Safety Statements | 22-26-36/37-45-36 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29339900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 |
|||||||||
| NFPA 704 |
|
Bicinchoninic Acid Disodium Salt price More Price(93)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | D8284 | Bicinchoninic acid disodium salt hydrate ≥98% (HPLC) | 979-88-4 | 1g | $87.4 | 2026-04-30 | Buy |
| Sigma-Aldrich | D8284 | Bicinchoninic acid disodium salt hydrate ≥98% (HPLC) | 979-88-4 | 5g | $254 | 2026-04-30 | Buy |
| TCI Chemical | B4509 | Bicinchoninic Acid Disodium Salt Hydrate >98.0%(HPLC)(T) | 979-88-4 | 1g | $24 | 2026-04-30 | Buy |
| TCI Chemical | B5838 | Bicinchoninic Acid Disodium Salt [for Protein Research] | 979-88-4 | 5G | $154 | 2026-04-30 | Buy |
| TCI Chemical | B4509 | Bicinchoninic Acid Disodium Salt Hydrate >98.0%(HPLC)(T) | 979-88-4 | 5g | $72 | 2026-04-30 | Buy |
Bicinchoninic Acid Disodium Salt Chemical Properties, Uses, Production
Description
2,2’-Biquinoline-4,4’-dicarboxylic acid (BCA) is a colorimetric reagent for the detection of copper (Cu+). BCA and Cu+ form a stable 2:1 complex that has an absorbance maximum at 562 nm. It is commonly used as a reagent in the colorimetric BCA protein quantitation assay in which Cu2+ is converted to Cu+ as a function of protein concentration under alkaline conditions.
Chemical Properties
White to light yellow powder.
IUPAC Name is disodium [2,2'-biquinoline]-4,4'-dicarboxylate
Uses
For determination of Cu and protein assays.Bicinchoninic acid disodium salt is useful for the determination of copper. It is also used for the determination of protein concentration.
Uses
- Bicinchoninic acid disodium salt hydrate has been used to monitor the levels of reducing sugars, thereby helping in the detection of chitinases.
- It has also been used to determine the amount of cellulose reducing ends (micromoles/g cellulose).
- It has been used for determining protein concentration.
Application
2,2'-Bicinchoninic Acid Disodium Salt is a photometric reagent for protein assay. It is used for determination of reducing sugar and protein via Cu(I). Also a specific reagent for Cu(I) with sensitivity similar to that of neocuproin.
Biochem/physiol Actions
Bicinchoninic acid is used for the determination of protein concentration. It is responsible for the making of intense purple complex with cuprous ion (Cu+), in presence of alkaline conditions. The amount of Cu+ is in relation with the protein concentration.
References
[1] P.K. SMITH. Measurement of protein using bicinchoninic acid[J]. Analytical biochemistry, 1985, 150 1: Pages 76-85. DOI: 10.1016/0003-2697(85)90442-7
[2] BRENNER A.J. Harris E D. A Quantitative Test for Copper Using Bicinchoninic Acid[J]. Analytical biochemistry, 1995, 226 1: Pages 80-84. DOI: 10.1006/abio.1995.1194
[3] WALKER J M. The bicinchoninic acid (BCA) assay for protein quantitation.[J]. Methods in molecular biology, 1994, 32: 5-8. DOI: 10.1385/0-89603-268-x:5
Bicinchoninic Acid Disodium Salt Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Suzhouhongxiong | 18051745768 | Suzhouhongxiong@163.com | China | 60 | 58 |
| Nanjing Search Biotech Co., Ltd | +86-025-81682922 +86-13515111588 | sales@searchbio.com.cn | China | 137 | 68 |
| Suzhou Haiheng Biological Pharmaceutical Co., Ltd. | 0512-65045967 15365387483 | sales@haihengpharm.com | China | 108 | 55 |
| Shanghai Youmede Technology Co., LTD | 18964944463 | 56810034@qq.com | China | 40 | 58 |
| Shanghai Hengmao Biotechnology Co. , Ltd. | 18817538189 | hmbsales@163.com | China | 101 | 58 |
| New Energy Chemicals | 0515-82159099 13770142076 | info@njuchem.com | China | 251 | 65 |
| Dalian Meilun Biotech Co., Ltd. | 0411-62910999 13889544652 | sales@meilune.com | China | 4765 | 58 |
| Shandong Kangsaide Biological Technology Co. LTD | 18615616891 | zhangdong.0602@163.com | China | 145 | 58 |
| Nodado Polysaccharide (Dalian) Pharmaceutical Technology Co., Ltd | 13840935583 13840935583 | nuodaduotang@163.com | China | 52 | 58 |
| Wuhan EnTai Technology Development Co,.Ltd | 86-27-82330560 | 2536851935@qq.com | China | 346 | 69 |
View Latest Price from Bicinchoninic Acid Disodium Salt manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-09-14 | BCA-2Na,2,2'-Biquinoline-4,4-dicarboxylic acid disodium salt
979-88-4
|
$100.00 | 1KG | 99% | 1000 KG | HANGZHOU DINGYAN CHEM CO.,LTD | |
![]() |
2026-09-14 | 2,2'-BICINCHONINIC acid disodium salt
979-88-4
|
$12.00-178.00 | 1g | 0.98 | 25kg | Shanghai UCHEM Inc. | |
![]() |
2026-09-11 | 2,2'-Biquinoline-4,4-dicarboxylic acid disodium salt
979-88-4
|
1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD |
-

- BCA-2Na,2,2'-Biquinoline-4,4-dicarboxylic acid disodium salt
979-88-4
- $100.00
- 99%
- HANGZHOU DINGYAN CHEM CO.,LTD
-

- 2,2'-BICINCHONINIC acid disodium salt
979-88-4
- $12.00-178.00
- 0.98
- Shanghai UCHEM Inc.
-

- 2,2'-Biquinoline-4,4-dicarboxylic acid disodium salt
979-88-4
- $0.00
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
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