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N1-(4-Butyl-2-methylphenyl)acetamide

N1-(4-Butyl-2-methylphenyl)acetamide structure

CAS No.: 143360-00-3

Chemical Name:: N1-(4-Butyl-2-methylphenyl)acetamide

Synonyms: CS-1090;SMIP004;SMIP-004;SMIP 004;SMIP 004; SMIP-004;SMIP004, 10 mM in DMSO;4-N-BUTYL-2-METHYLACETANILIDE;4'-(But-1-yl)-2'-methylacetanilide;N-(4-Butyl-2-methylphenyl)acetamide;SKP2 E3 Ligase Inhibitor II, SMIP004

CBNumber:: CB6320959

Molecular Formula:: C13H19NO

Molecular Weight:: 205.3

MDL Number:: MFCD00277686

MOL File:: 143360-00-3.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-09-12 18:54:12

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N1-(4-Butyl-2-methylphenyl)acetamide Properties

Boiling point	343.0±21.0 °C(Predicted)
Density	1.003±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	≥ 20.5 mg/mL in DMSO, ≥ 53.6 mg/mL in EtOH with ultrasonic
pka	15.14±0.70(Predicted)
form	Solid
color	White to off-white
InChI	1S/C13H19NO/c1-4-5-6-12-7-8-13(10(2)9-12)14-11(3)15/h7-9H,4-6H2,1-3H3,(H,14,15)
InChIKey	ZFVMECVBUGMWIX-UHFFFAOYSA-N
SMILES	N(c1c(cc(cc1)CCCC)C)C(=O)C
UNSPSC Code	12352200
NACRES	NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302+H312+H332-H315-H319-H335

Precautionary statements

P280

WGK Germany

WGK 2

HS Code

2924297099

Storage Class

11 - Combustible Solids

NFPA 704

	1
2		0

N1-(4-Butyl-2-methylphenyl)acetamide price More Price(67)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	5.00517	SKP2 E3 Ligase Inhibitor II, SMIP004 - CAS 143360-00-3 - Calbiochem	143360-00-3	25MG	$277	2026-04-30	Buy
Cayman Chemical	40645	SMIP004 ≥98%	143360-00-3	1mg	$28	2026-04-30	Buy
Cayman Chemical	40645	SMIP004 ≥98%	143360-00-3	5mg	$104	2026-04-30	Buy
Cayman Chemical	40645	SMIP004 ≥98%	143360-00-3	10mg	$165	2026-04-30	Buy
Cayman Chemical	40645	SMIP004 ≥98%	143360-00-3	25mg	$275	2026-04-30	Buy

Product number	Packaging	Price	Buy
5.00517	25MG	$277	Buy
40645	1mg	$28	Buy
40645	5mg	$104	Buy
40645	10mg	$165	Buy
40645	25mg	$275	Buy

N1-(4-Butyl-2-methylphenyl)acetamide Chemical Properties, Uses, Production

Uses

SMIP004 is a SKP2 E3 ligase inhibitor, which downregulates SKP2 and to stabilise p27. SMIP004 is a cancer cell selective apoptosis inducer of human prostate cancer cells[1][2].

Biological Activity

Cell permeable: yes', 'Reversible: yes

in vivo

SMIP004 potently inhibits the growth of prostate and breast cancer xenografts in SCID mice^[2].

storage

Store at -20°C

References

[1] Li C, et al. SKP2 promotes breast cancer tumorigenesis and radiation tolerance through PDCD4 ubiquitination. J Exp Clin Cancer Res. 2019 Feb 13;38(1):76. DOI:10.1186/s13046-019-1069-3
[2] Rico-Bautista E, Zhu W, Kitada S, Small Molecule-Induced Mitochondrial Disruption Directs Prostate Cancer Inhibition via UPR Signaling. Oncotarget. 2013 Jul 14. DOI:10.18632/oncotarget.1130

N1-(4-Butyl-2-methylphenyl)acetamide Preparation Products And Raw materials

Raw materials

Preparation Products

N1-(4-Butyl-2-methylphenyl)acetamide Suppliers

Global Suppliers ( 88)

Supplier	Tel	Email	Country	ProdList	Advantage
Haoyuan Chemexpress Co., Ltd.	021-58950125	info@chemexpress.com	China	7545	61
LETOPHARM LIMITED	+86-21-5821 5861	sales@letopharm.com	China	2374	58
SPIRO PHARMA		eric_feng1954@126.com	China	9239	55
Guangzhou QiYun Biotechnology Co., Ltd.	020-61288194 61288195	505721671@qq.com	China	3853	58
Chengdu Huachun Technology Co., Ltd	400-1166-196 15982826727	cdhxsj@163.com	China	14571	60
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131885	58
MQ (shanghai) Pharmaceuticals Co., Ltd.	13761635123	sales@linyuepharm.com	China	5731	55
Musechem	+1-800-259-7612	info@musechem.com	United States	4648	60
Twochem Co.Ltd.	021-58111628 15800915896	sales@twochem.com	China	1782	58
Tianjin Kaifu Pharmaceutical Technology Co., Ltd.	18081075745	chemflowtech@sina.com	China	1883	58

Supplier	Advantage
Haoyuan Chemexpress Co., Ltd.	61
LETOPHARM LIMITED	58
SPIRO PHARMA	55
Guangzhou QiYun Biotechnology Co., Ltd.	58
Chengdu Huachun Technology Co., Ltd	60
Amadis Chemical Company Limited	58
MQ (shanghai) Pharmaceuticals Co., Ltd.	55
Musechem	60
Twochem Co.Ltd.	58
Tianjin Kaifu Pharmaceutical Technology Co., Ltd.	58

N1-(4-Butyl-2-methylphenyl)acetamide Spectrum

N1-(4-BUTYL-2-METHYLPHENYL)ACETAMIDE(143360-00-3)¹HNMR

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