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ChemicalBook >> CAS DataBase List >>(1H-Pyrrolo[2,3-b]pyridin-5-yl)-methanol

(1H-Pyrrolo[2,3-b]pyridin-5-yl)-methanol

(1H-Pyrrolo[2,3-b]pyridin-5-yl)-methanol Structure
(1H-Pyrrolo[2,3-b]pyridin-5-yl)-methanol structure
CAS No.
849067-97-6
Chemical Name:
(1H-Pyrrolo[2,3-b]pyridin-5-yl)-methanol
Synonyms
5-HYDROXYMETHYL-7-AZAINDOLE;1H-Pyrrolo[2,3-b]pyridine-5-methanol;(1H-Pyrrolo[2,3-b]pyridin-5-yl)-methanol;5-(hydroxyMethyl)-1h-pyrrolo[2,3-b]pyridine
CBNumber:
CB6322993
Molecular Formula:
C8H8N2O
Molecular Weight:
148.16
MDL Number:
MFCD08457786
MOL File:
849067-97-6.mol
MSDS File:
SDS
Last updated:2026-09-12 18:54:12
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(1H-Pyrrolo[2,3-b]pyridin-5-yl)-methanol Properties

Melting point 126-127°C
Density 1.360±0.06 g/cm3(Predicted)
storage temp. 2-8°C
form solid
pka 13.84±0.10(Predicted)
Appearance White to off-white Solid
InChI 1S/C8H8N2O/c11-5-6-3-7-1-2-9-8(7)10-4-6/h1-4,11H,5H2,(H,9,10)
InChIKey HECHZAPQJASYJL-UHFFFAOYSA-N
SMILES OCc1cnc2[nH]ccc2c1
UNSPSC Code 12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405-P501
Hazard Codes  Xi
WGK Germany  3
HazardClass  IRRITANT
HS Code  2933998090
Storage Class 11 - Combustible Solids

(1H-Pyrrolo[2,3-b]pyridin-5-yl)-methanol price More Price(37)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich ADE000893 (1H-Pyrrolo[2,3-b]pyridin-5-yl)-methanol Aldrich 849067-97-6 1g $870 2026-04-30 Buy
Apolloscientific OR345425 5-Hydroxymethyl-7-azaindole 99% 849067-97-6 100mg $28 2026-06-04 Buy
Apolloscientific OR345425 5-Hydroxymethyl-7-azaindole 99% 849067-97-6 250mg $33 2026-06-04 Buy
Apolloscientific OR345425 5-Hydroxymethyl-7-azaindole 99% 849067-97-6 1g $128 2026-06-04 Buy
Apolloscientific OR345425 5-Hydroxymethyl-7-azaindole 99% 849067-97-6 5g $614 2026-06-04 Buy
Product number Packaging Price Buy
ADE000893 1g $870 Buy
OR345425 100mg $28 Buy
OR345425 250mg $33 Buy
OR345425 1g $128 Buy
OR345425 5g $614 Buy

(1H-Pyrrolo[2,3-b]pyridin-5-yl)-methanol Chemical Properties, Uses, Production

Uses

(1H-Pyrrolo[2,3-b]pyridin-5-yl)methanol is used as a pharmaceutical intermediate.

Synthesis

1H-PYRROLO[2,3-B]PYRIDINE-5-CARBOXYLIC ACID METHYL ESTER

849067-96-5

(1H-PYRROLO[2,3-B]PYRIDIN-5-YL)-METHANOL

849067-97-6

General procedure for the synthesis of (1H-pyrrolo[2,3-b]pyridin-5-yl)methanol from methyl 1H-pyrrolo[2,3-b]pyridine-5-carboxylate: Step C: Preparation of (1H-pyrrolo[2,3-b]pyridin-5-yl)methanol [0249] Methyl 1H-pyrrolo[2,3-b]pyridine-5-carboxylate (75 mg, 0.394 mmol) was dissolved in THF at 0 °C and lithium aluminum hydride (45 mg, 1.18 mmol) was added slowly. The reaction mixture was gradually warmed to room temperature followed by refluxing for 12 hours. After completion of the reaction, it was cooled to room temperature and quenched with water. The reaction mixture was extracted with ethyl acetate, the organic phase was washed with brine, dried over anhydrous sodium sulfate and concentrated to give (1H-pyrrolo[2,3-b]pyridin-5-yl)methanol (57 mg, 98% yield). Product characterization data: 1H NMR (500 MHz, DMSO-d6) δ: 11.50 (1H, bs), 8.166-8.163 (1H, d), 7.862-7.860 (1H, d), 7.43-7.42 (1H, d), 6.41-6.40 (1H, d), 5.10-5.08 (1H, t), 4.58-4.57 ( 2H, d). FIA MS, m/z [MH]+ 149.1.

References

[1] Patent: WO2005/28475, 2005, A2. Location in patent: Page/Page column 142-143; 222

(1H-Pyrrolo[2,3-b]pyridin-5-yl)-methanol synthesis

849067-90-9
849067-97-6
Synthesis of (1H-Pyrrolo[2,3-b]pyridin-5-yl)-methanol from 7-Azaindole-5-carboxaldehyde

(1H-Pyrrolo[2,3-b]pyridin-5-yl)-methanol Preparation Products And Raw materials

Raw materials

1H-Pyrrolo[2,3-b]pyridine-5-carboxylic acid methyl ester 7-Azaindole-5-carboxaldehyde Tetrahydrofuran Lithium Aluminum Hydride

Preparation Products

(1H-Pyrrolo[2,3-b]pyridin-5-yl)-methanol Suppliers

Global Suppliers ( 61)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8663 57
Dtchem Laboratories,（Gan Su）Co.,Ltd. 18993961550 18993966060 sales@techbiochem.com China 773 61
Wuhan TCASChem Technology Co., Ltd. 027-86697669 13986148687 sales@tcaschem.com China 3988 55
Shanghai Devinchem Ltd 027-65318838 13646286950 sales@devinchem.com China 2996 58
Shanghai Xingui Biotechnology Co., Ltd. 15121041756 xingui2022@126.com China 9985 58
SPIRO PHARMA eric_feng1954@126.com China 9239 55
SuZhou ShiYa Biopharmaceuticals, Inc. 0512-0512-52358471 17715136450 sales@shiyabiopharm.com China 9814 58
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Wuhan Chemwish Technology Co., Ltd 56
Capot Chemical Co., Ltd 66
Shanghai Sunway Pharmaceutical Technology Co., Ltd 57
Dtchem Laboratories,（Gan Su）Co.,Ltd. 61
Wuhan TCASChem Technology Co., Ltd. 55
Shanghai Devinchem Ltd 58
Shanghai Xingui Biotechnology Co., Ltd. 58
SPIRO PHARMA 55
SuZhou ShiYa Biopharmaceuticals, Inc. 58

View Latest Price from (1H-Pyrrolo[2,3-b]pyridin-5-yl)-methanol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(1H-PYRROLO[2,3-B]PYRIDIN-5-YL)-METHANOL pictures 2019-07-06 (1H-PYRROLO[2,3-B]PYRIDIN-5-YL)-METHANOL
849067-97-6
 $7.00 1kg 99% 100KG Career Henan Chemical Co

(1H-Pyrrolo[2,3-b]pyridin-5-yl)-methanol Spectrum

(1H-PYRROLO[2,3-B]PYRIDIN-5-YL)-METHANOL(849067-97-6)1HNMR

849067-97-6 ((1H-Pyrrolo[2,3-b]pyridin-5-yl)-methanol) Related Search:

(4-Methoxy-1H-pyrrolo[2,3-b]pyridin-2-yl)methanol 1H-Pyrrolo[2,3-b]pyridine-5-carboxylic acid (5-Methoxy-1H-pyrrolo[3,2-b]pyridin-2-yl)methanol (5-Methoxy-1H-pyrrolo[2,3-c]pyridin-2-yl)methanol (4-Chloro-1-methyl-1H-pyrrolo[3,2-c]pyridin-3-yl)methanol
5-Dimethoxymethyl-1H-pyrrolo[2,3-b]pyridine 1-Methyl-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid Methyl 4-(4-fluorophenyl)-6-isopropyl-1H-pyrrolo[2,3-b]pyridine-5-carboxylate (1H-Pyrrolo[2,3-b]pyridin-5-yl)-methanol 1H-Pyrrolo[2,3-b]pyridine-5-carboxylic acid methyl ester
(1H-Pyrrolo[3,2-b]pyridin-6-yl)methanol (1H-Pyrrolo[2,3-c]pyridin-2-yl)-methanol 3-Iodo-1H-pyrrolo[2,3-b]pyridine-5-carboxylicacidmethylester 1H-Pyrrolo[2,3-b]pyridine-5-carboxylic acid, 4-chloro- 1H-Pyrrolo[2,3-b]pyridine-5-carboxylic acid, 6-methyl-
(4-Chloro-1H-pyrrolo[2,3-b]pyridin-5-yl)methanol (4-chlorophenyl)[1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]methanol (5-Benzyloxy-1H-pyrrolo[2,3-c]pyridin-3-yl)-methanol

1of4

5-HYDROXYMETHYL-7-AZAINDOLE 1H-Pyrrolo[2,3-b]pyridine-5-methanol 5-(hydroxyMethyl)-1h-pyrrolo[2,3-b]pyridine (1H-Pyrrolo[2,3-b]pyridin-5-yl)-methanol 849067-97-6 936549-95-1