ZK756326(dihydrochloride)
- CAS No.
- 1780259-94-0
- Chemical Name:
- ZK756326(dihydrochloride)
- Synonyms
- ZK 756326 (hydrochloride);ZK756326(dihydrochloride);ZK 756326, non-peptide CCR8 chemokine receptor agonist
- CBNumber:
- CB63356182
- Molecular Formula:
- C21H29ClN2O3
- Molecular Weight:
- 392.92
- MDL Number:
- MFCD09038571
- MOL File:
- 1780259-94-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| storage temp. | Store at -20°C |
|---|---|
| solubility | PBS (pH 7.2): 10 mg/ml |
| form | A crystalline solid |
| color | White to off-white |
| InChI | InChI=1S/C21H28N2O3.ClH/c24-14-16-25-15-13-22-9-11-23(12-10-22)18-19-5-4-8-21(17-19)26-20-6-2-1-3-7-20;/h1-8,17,24H,9-16,18H2;1H |
| InChIKey | GPPMZVONOXAYET-UHFFFAOYSA-N |
| SMILES | C(N1CCN(CCOCCO)CC1)C1C=CC=C(OC2C=CC=CC=2)C=1.Cl |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
ZK756326(dihydrochloride) price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 28454 | ZK 756326 (hydrochloride) ≥98% | 1780259-94-0 | 5mg | $112 | 2026-04-30 | Buy |
| Cayman Chemical | 28454 | ZK 756326 (hydrochloride) ≥98% | 1780259-94-0 | 10mg | $201 | 2026-04-30 | Buy |
| Cayman Chemical | 28454 | ZK 756326 (hydrochloride) ≥98% | 1780259-94-0 | 25mg | $439 | 2026-04-30 | Buy |
| Biosynth | FWC25994 | ZK756326 dihydrochloride | 1780259-94-0 | 50mg | $1149.5 | 2026-06-04 | Buy |
| ChemScene | CS-7558 | ZK756326 dihydrochloride 99.87% | 1780259-94-0 | 5mg | $65 | 2026-06-04 | Buy |
ZK756326(dihydrochloride) Chemical Properties, Uses, Production
Uses
ZK756326 dihydrochloride is a nonpeptide chemokine receptor agonist for the CC chemokine receptor CCR8.
IC 50
CCR8: 1.8 μM (IC50, in U87 cells); 5-HT2B: 4.4 μM (IC50); 5-HT1A: 5.4 μM (IC50); 5-HT6: 5.9 μM (IC50); 5-HT5A: 16 μM (IC50); 5-HT2C: 34.8 μM (IC50); α2A: <20 μM (IC50)
References
[1] Haskell CA, et al. Identification and characterization of a potent, selective nonpeptide agonist of the CC chemokine receptor CCR8. Mol Pharmacol. 2006 Jan;69(1):309-16. DOI:10.1124/mol.105.014779
ZK756326(dihydrochloride) Preparation Products And Raw materials
Raw materials
Preparation Products
ZK756326(dihydrochloride) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou Chenhong Biotechnology Co., Ltd. | +86-0519-85788828 +86-13775037613 | sales@chemrenpharm.com | China | 4058 | 58 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4853 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| Shanghai Chaolan Chemical Technology Center | QQ：65489617 13301690235 | Sales@ATKchemical.com | China | 9729 | 58 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 17801761073 18101056239 | 3193328036@qq.com | China | 28150 | 68 |
| Twochem Co.Ltd. | 021-58111628 15800915896 | sales@twochem.com | China | 1782 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 400-920-5774 | sales@glpbio.cn | China | 6705 | 58 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9718 | 58 |
