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ZK-261991

ZK-261991 Structure
ZK-261991 structure
CAS No.
886563-25-3
Chemical Name:
ZK-261991
Synonyms
ZK-991;ZK 991;ZK-261991;ZK261991(ZK991);ZK 261991,ZK261991;ZK261991;ZK-261991;ZK 261991;ZK-991;ZK 991;Benzamide, 2-[[[2-[[(dimethylamino)carbonyl]amino]-4-pyridinyl]methyl]amino]-N-(2-methyl-2H-indazol-6-yl)-
CBNumber:
CB02628541
Molecular Formula:
C24H25N7O2
Molecular Weight:
443.5
MDL Number:
MFCD25976709
MOL File:
886563-25-3.mol
MSDS File:
SDS
Last updated:2026-07-27 17:00:41
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ZK-261991 Properties

storage temp. Store at -20°C
solubility Soluble in DMSO

ZK-261991 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth LKB56325 ZK 261991 886563-25-3 5mg $1670.55 2026-06-04 Buy
Biosynth LKB56325 ZK 261991 886563-25-3 10mg $2672.8 2026-06-04 Buy
Biosynth LKB56325 ZK 261991 886563-25-3 25mg $5011.5 2026-06-04 Buy
Biosynth LKB56325 ZK 261991 886563-25-3 50mg $8018.5 2026-06-04 Buy
Product number Packaging Price Buy
LKB56325 5mg $1670.55 Buy
LKB56325 10mg $2672.8 Buy
LKB56325 25mg $5011.5 Buy
LKB56325 50mg $8018.5 Buy

ZK-261991 Chemical Properties, Uses, Production

Uses

ZK-261991 is an orally active VEGFR tyrosine kinase inhibitor with an IC50 of 5 nM for VEGFR2.

in vivo

ZK991 results in a significantly reduced recruitment of CD11b+ and LYVE-1+ cells into the murine cornea. ZK991 significantly improves the graft survival rate after corneal transplantation[1].

IC 50

VEGFR2: 5 nM (IC50)

References

[1] Deniz Hos, et al. Inflammatory Corneal (Lymph)angiogenesis Is Blocked by VEGFR-Tyrosine Kinase Inhibitor ZK 261991, Resulting in Improved Graft Survival after Corneal Transplantation. Investigative Ophthalmology & Visual Science May 2008, Vol.49, 1836-184

ZK-261991 Preparation Products And Raw materials

Raw materials

Preparation Products

ZK-261991 Suppliers

Global Suppliers ( 11)
Supplier Tel Email Country ProdList Advantage
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4853 58
SPIRO PHARMA eric_feng1954@126.com China 9239 55
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
cjbscvictory 13348960310 13348960310 3003867561@qq.com China 10233 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58
TargetMol Chemicals Inc. +1-781-999-5354; support@targetmol.com United States 38999 58
Supplier Advantage
MedChemexpress LLC 58
SPIRO PHARMA 55
TargetMol Chemicals Inc. 58
cjbscvictory 58
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58

View Latest Price from ZK-261991 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
ZK-261991 pictures 2026-07-27 ZK-261991
886563-25-3
 $1520.00-2500.00 10g TargetMol Chemicals Inc.
ZK-261991 pictures 2026-07-27 ZK-261991
886563-25-3
 $1520.00-2500.00 10g TargetMol Chemicals Inc.
ZK-261991 pictures 2025-07-17 ZK-261991
886563-25-3
 $1520.00-2500.00 10g TargetMol Chemicals Inc.
  • ZK-261991 pictures
  • ZK-261991
    886563-25-3
  • $1520.00-2500.00
  • TargetMol Chemicals Inc.
  • ZK-261991 pictures
  • ZK-261991
    886563-25-3
  • $1520.00-2500.00
  • TargetMol Chemicals Inc.
  • ZK-261991 pictures
  • ZK-261991
    886563-25-3
  • $1520.00-2500.00
  • TargetMol Chemicals Inc.

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1of3

ZK-261991 ZK261991(ZK991) ZK 991 ZK261991;ZK-261991;ZK 261991;ZK-991;ZK 991 ZK-991 Benzamide, 2-[[[2-[[(dimethylamino)carbonyl]amino]-4-pyridinyl]methyl]amino]-N-(2-methyl-2H-indazol-6-yl)- ZK 261991,ZK261991 886563-25-3