3-(Benzyloxy)-5-bromopyridine
- CAS No.
- 130722-95-1
- Chemical Name:
- 3-(Benzyloxy)-5-bromopyridine
- Synonyms
- B67304;3-Bromo-5-bezyloxypyridine;5-Benzyloxy-3-broMopyridine;3-(Benzyloxy)-5-bromopyridine;3-Benzyloxy-5-bromopyridine >3-bromo-5-phenylmethoxypyridine;3-(Benzyloxy)-5-bromopyridine ,97%;Pyridine, 3-bromo-5-(phenylmethoxy)-;C12H10BrNO 3-(BENZYLOXY)-5-BROMOPYRIDINE;3-(BENZYLOXY)-5-BROMOPYRIDINE ISO 9001：2015 REACH
- CBNumber:
- CB6406909
- Molecular Formula:
- C12H10BrNO
- Molecular Weight:
- 264.12
- MDL Number:
- MFCD07375004
- MOL File:
- 130722-95-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 69.0 to 73.0 °C |
|---|---|
| Boiling point | 343.7±27.0 °C(Predicted) |
| Density | 1.438±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| form | powder to crystal |
| pka | 2.23±0.10(Predicted) |
| color | White to Light yellow |
| λmax | 290nm(MeOH)(lit.) |
| InChI | InChI=1S/C12H10BrNO/c13-11-6-12(8-14-7-11)15-9-10-4-2-1-3-5-10/h1-8H,9H2 |
| InChIKey | YSHKYZAWTWKQKK-UHFFFAOYSA-N |
| SMILES | C1=NC=C(OCC2=CC=CC=C2)C=C1Br |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36/37/39 |
| HS Code | 29333990 |
3-(Benzyloxy)-5-bromopyridine price More Price(58)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | B4775 | 3-Benzyloxy-5-bromopyridine >98.0%(GC)(T) | 130722-95-1 | 1g | $57 | 2026-04-30 | Buy |
| TCI Chemical | B4775 | 3-Benzyloxy-5-bromopyridine >98.0%(GC)(T) | 130722-95-1 | 5g | $194 | 2026-04-30 | Buy |
| AstaTech | 52562 | 3-(BENZYLOXY)-5-BROMOPYRIDINE 97% | 130722-95-1 | 5G | $68 | 2026-04-30 | Buy |
| AstaTech | 52562 | 3-(BENZYLOXY)-5-BROMOPYRIDINE 97% | 130722-95-1 | 25G | $205 | 2026-04-30 | Buy |
| Apolloscientific | OR345016 | 3-Benzyloxy-5-bromopyridine >97% | 130722-95-1 | 5g | $21 | 2026-06-04 | Buy |
3-(Benzyloxy)-5-bromopyridine Chemical Properties, Uses, Production
Chemical Properties
White solid
Synthesis
625-92-3
100-51-6
130722-95-1
1. benzyl alcohol (4.60 g, 42.6 mmol) was slowly added dropwise to a stirred suspension of sodium hydride (60% mineral oil dispersion, 1.70 g, 42.5 mmol) in dimethylformamide (DMF, 50 mL) under dry conditions. 2. the reaction mixture was heated to 60 °C and stirred at this temperature for 1 h to ensure complete deprotonation. 3. 3,5-dibromopyridine (10.0 g, 42.2 mmol) was dissolved in dimethylformamide (DMF, 20 mL) and this solution was subsequently added to the above reaction mixture. 4. The reaction system was warmed to 80 °C and the reaction was continued with stirring for 2 hours to complete the nucleophilic substitution reaction. 5. Upon completion of the reaction, the reaction mixture was cooled to room temperature and subsequently separated by extraction with ethyl acetate and water. 6. The organic layer was separated and dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give the crude product. 7. The crude product was purified by fast column chromatography to afford the target compound 3-benzyloxy-5-bromopyridine (4.75 g, 43% yield). 8. Mass spectrometry (MS) analysis showed the following: m/z calculated value (M + H) + 265, measured value 265, as expected.
References
[1] Bioorganic and Medicinal Chemistry Letters, 2006, vol. 16, # 12, p. 3150 - 3155
[2] Journal of Medicinal Chemistry, 2012, vol. 55, # 2, p. 717 - 724
[3] Patent: US2013/184313, 2013, A1. Location in patent: Paragraph 1099; 1100
[4] Tetrahedron, 2011, vol. 67, # 26, p. 4767 - 4773
[5] Tetrahedron, 2001, vol. 57, # 20, p. 4447 - 4454
3-(Benzyloxy)-5-bromopyridine Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Beijing HengPuGao Pharmaceutical Chemistry Technology Co., Ltd. | 010-81520996 13439320863 | hengpugao@126.com | China | 159 | 57 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Tetranov Biopharm | 13526569071 | sales@leadmedpharm.com | China | 7881 | 64 |
| Beijing Yisiyan Technology Research Center | 010-56645598 13366904824; | bjkaida@163.com | China | 1596 | 59 |
| Chengdu NoVi Biotechnology Co., Ltd. | 028-81458053 | novibiotech@163.com sales@novi-biotech.com | China | 226 | 55 |
| TOKYO CHEMICAL INDUSTRY CO., LTD. | 03-36680489 | Sales-JP@TCIchemicals.com | Japan | 28364 | 80 |
| TCI Europe | 320-37350700 | sales@tcieurope.eu | Europe | 23654 | 75 |
| TCI AMERICA | 800-4238616 | sales@tciamerica.com | Americas | 23636 | 75 |
View Latest Price from 3-(Benzyloxy)-5-bromopyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | 3-(BENZYLOXY)-5-BROMOPYRIDINE
130722-95-1
|
$1.10 | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited | |
 |
2022-04-22 | 3-Benzyloxy-5-bromopyridine
130722-95-1
|
98%min | 100kgs/month | Shanghai Rlavie Technology Co ltd | |||
 |
2020-05-13 | 3-Benzyloxy-5-Bromo-Pyridine
130722-95-1
|
1KG | 99.0% | 500 MT | Shaanxi Dideu Medichem Co. Ltd |
-
- 3-(BENZYLOXY)-5-BROMOPYRIDINE
130722-95-1
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 3-Benzyloxy-5-bromopyridine
130722-95-1
- 98%min
- Shanghai Rlavie Technology Co ltd
-
- 3-Benzyloxy-5-Bromo-Pyridine
130722-95-1
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
