3-Bromo-5-methylpyridine
- CAS No.
- 3430-16-8
- Chemical Name:
- 3-Bromo-5-methylpyridine
- Synonyms
- 3-brmo-5-me;3-Bromo-5-methyL;5-BROMO-3-PICOLINE;3-BROMO-5-METHYLPY...;3-brmo-5-methylpyridine;3-methy-5-bromopyridine;3-BROMO-5-METHYLPYRIDINE;3-Methyl-5-Bromopyridine;Pyridine, 3-bromo-5-methyl-;3-Bromo-5-methylpyridine >
- CBNumber:
- CB7416792
- Molecular Formula:
- C6H6BrN
- Molecular Weight:
- 172.02
- MDL Number:
- MFCD01646141
- MOL File:
- 3430-16-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 3-Bromo-5-methylpyridine 97% | 681245 | 250mg | $128 |
| 3-Bromo-5-methylpyridine >98.0%(GC)(T) | B3724 | 1g | $36 |
| 3-Bromo-5-methylpyridine >98.0%(GC)(T) | B3724 | 5g | $141 |
| 5-BROMO-3-PICOLINE 97% | 53604 | 1G | $17 |
| 3-Bromo-5-methylpyridine ≥99%(GC) | 17060 | 1G | $18.53 |
| More product size | |||
| Melting point | 16.5-16.7 °C |
|---|---|
| Boiling point | 110°C/25mmHg(lit.) |
| Density | 1.4869 g/mL at 25 °C |
| refractive index | 1.5618 |
| Flash point | 91 °C |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| pka | 3.16±0.20(Predicted) |
| form | powder to lump to clear liquid |
| color | White or Colorless to Almost white or Almost colorless |
| InChI | 1S/C6H6BrN/c1-5-2-6(7)4-8-3-5/h2-4H,1H3 |
| InChIKey | ADCLTLQMVAEBLB-UHFFFAOYSA-N |
| SMILES | Cc1cncc(Br)c1 |
| CAS DataBase Reference | 3430-16-8(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H318 | |||||||||
| Precautionary statements | P264-P270-P280-P301+P312-P305+P351+P338-P501 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-41-22 | |||||||||
| Safety Statements | 26-36/37/39-39 | |||||||||
| RIDADR | NA 1993 / PGIII | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2933399990 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Dam. 1 |
|||||||||
| NFPA 704 |
|
3-Bromo-5-methylpyridine price More Price(52)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 681245 | 3-Bromo-5-methylpyridine 97% | 3430-16-8 | 250mg | $128 | 2023-06-20 | Buy |
| TCI Chemical | B3724 | 3-Bromo-5-methylpyridine >98.0%(GC)(T) | 3430-16-8 | 1g | $36 | 2026-04-30 | Buy |
| TCI Chemical | B3724 | 3-Bromo-5-methylpyridine >98.0%(GC)(T) | 3430-16-8 | 5g | $141 | 2026-04-30 | Buy |
| AstaTech | 53604 | 5-BROMO-3-PICOLINE 97% | 3430-16-8 | 1G | $17 | 2026-04-30 | Buy |
| Chem-Impex | 17060 | 3-Bromo-5-methylpyridine ≥99%(GC) | 3430-16-8 | 1G | $18.53 | 2026-05-19 | Buy |
3-Bromo-5-methylpyridine Chemical Properties,Uses,Production
Chemical Properties
Light yellow liquid
Uses
5-Bromo-3-picoline is an intermediate of pyridinyl pyrrole compounds as proton pump inhibitors with improved gastric acid secretion suppressive activity
Synthesis
625-92-3
823-96-1
3430-16-8
The general procedure for the synthesis of 3-bromo-5-methylpyridine from 3,5-dibromopyridine and trimethylcyclotriboroxane was as follows: under nitrogen protection, cesium carbonate (1.38 g, 4.22 mmol), trimethylcyclotriboroxane (0.2 mL, 1.47 mmol), and tetrakis(triphenylphosphine)palladium(0) (0.488 g, 0.42 mmol ). Subsequently, a solution of 3,5-dibromopyridine (1.0 g, 4.22 mmol) dissolved in a 9:1 solvent mixture of dioxane and water (10 mL) was added. The reaction mixture was stirred at 110 °C for 16 hours. Upon completion of the reaction, trimethylcyclotriboroxane (0.2 mL, 1.47 mmol) was added again and the reaction temperature was lowered to 100 °C and the reaction continued to be stirred for 16 hours. At the end of the reaction, the reaction mixture was cooled to room temperature, filtered through diatomaceous earth and the filter cake was washed with ethyl acetate. The filtrate was concentrated and the resulting residue was purified by silica gel column chromatography with the eluent being a 80:20 solvent mixture of hexane and ethyl acetate, resulting in 3-bromo-5-methylpyridine as a colorless oil (0.654 g, 90% yield). The product was identified by 1H NMR (300 MHz, CDCl3): δ 2.34 (s, 3H), 7.66 (s, 1H), 8.36 (s, 1H), 8.49 (s, 1H).GC-MS (EI) analysis showed: m/z = 171.0, 173.0 [M].
References
[1] Patent: WO2005/94822, 2005, A1. Location in patent: Page/Page column 25
3-Bromo-5-methylpyridine Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20124 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29816 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2994 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29794 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10000 | 58 |
View Lastest Price from 3-Bromo-5-methylpyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-12-01 | 3-Bromo-5-methylpyridine
3430-16-8
|
US $0.00-0.00 / KG | 1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | |
 |
2025-11-18 | 3-Bromo-5-methylpyridine
3430-16-8
|
US $1.10 / g | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited | |
 |
2025-09-25 | 3-Bromo-5-methylpyridine
3430-16-8
|
US $5.00-0.10 / KG | 1KG | 98% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd |
-
- 3-Bromo-5-methylpyridine
3430-16-8
- US $0.00-0.00 / KG
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
-
- 3-Bromo-5-methylpyridine
3430-16-8
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
-
- 3-Bromo-5-methylpyridine
3430-16-8
- US $5.00-0.10 / KG
- 98%
- Henan Fengda Chemical Co., Ltd
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