Fmoc-L-cyclopropylglycine
- CAS No.
- 1212257-18-5
- Chemical Name:
- Fmoc-L-cyclopropylglycine
- Synonyms
- (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-cyclopropylacetic acid;Fmoc-L-Gly(cPr)-OH;Fmoc-L-Cyclopropylgly;Fmoc-CyclopropylGly-OH;Fmoc-L-cyclopropylglycine;(S)-Fmoc-cyclopropylglycine;Fmoc-(S)-2-cyclopropylglycine;N-Fmoc-S-2-Cyclopropylglycine;FMOC-L-CYCLOPROPYLGLYCINE ,98% min;Fmoc-(S)-Amino-cyclopropyl-acetic acid
- CBNumber:
- CB6409672
- Molecular Formula:
- C20H19NO4
- Molecular Weight:
- 337.37
- MDL Number:
- MFCD06659145
- MOL File:
- Mol file
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 577.1±33.0 °C(Predicted) |
|---|---|
| Density | 1.332±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| pka | 3.85±0.10(Predicted) |
| form | powder |
| color | White |
| optical activity | 17.134°(C=0.01g/ml DCM) |
| InChI | InChI=1S/C20H19NO4/c22-19(23)18(12-9-10-12)21-20(24)25-11-17-15-7-3-1-5-13(15)14-6-2-4-8-16(14)17/h1-8,12,17-18H,9-11H2,(H,21,24)(H,22,23)/t18-/m0/s1 |
| InChIKey | YMLZBPTXRMNAFP-SFHVURJKSA-N |
| SMILES | C1(COC(=O)N[C@H](C(O)=O)C2CC2)C2C=CC=CC=2C2C=CC=CC=21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H335-H315-H319 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
| Hazard Codes | Xi |
| HS Code | 2922498590 |
Fmoc-L-cyclopropylglycine price More Price(58)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 277693 | Fmoc-L-cyclopropylglycine Asreported | 1212257-18-5 | 50mg | $333 | 2026-06-03 | Buy |
| Usbiological | 277693 | Fmoc-L-cyclopropylglycine Asreported | 1212257-18-5 | 100mg | $456 | 2026-06-03 | Buy |
| Usbiological | 277693 | Fmoc-L-cyclopropylglycine Asreported | 1212257-18-5 | 250mg | $552 | 2026-06-03 | Buy |
| Usbiological | 277693 | Fmoc-L-cyclopropylglycine Asreported | 1212257-18-5 | 500mg | $722 | 2026-06-03 | Buy |
| Usbiological | 277693 | Fmoc-L-cyclopropylglycine Asreported | 1212257-18-5 | 1g | $1117 | 2026-06-03 | Buy |
Fmoc-L-cyclopropylglycine Chemical Properties,Uses,Production
Chemical Properties
White powder
Uses
Fmoc-L-cyclopropylglycine is used in preparation of tailored Cyclodepsipeptides as potent non-covalent serine protease inhibitors.
Synthesis
28920-43-6
49606-99-7
1212257-18-5
GENERAL STEPS: 2.3 g of Na2CO3 was dissolved in 34 mL of water and chloroformic acid-9-fluorenylmethyl ester and (S)-2-amino-2-cyclopropylacetic acid were added with stirring. The reaction mixture was stirred at room temperature. After completion of the reaction, the product was characterized by FT-IR and NMR.FT-IR (pure): 2669, 2335, 2159, 2106, 1785, 1689, 1550, 1489, 1463, 1433, 1369, 1296, 1253, 1172, 1128, 1001 cm^-1.^1H NMR ( CDCl3, 600 MHz): δ = 7.76 (d, 2H, J = 7.2 Hz), 7.60-7.59 (m, 2H), 7.41-7.39 (m, 2H), 7.32-7.30 (m, 2H), 5.36 (d, 1H, J = 6 Hz), 4.45-4.39 (m, 2H), 4.24-4.21 (m, 1H ), 3.83-3.81 (m, 1H), 1.14-1.13 (m, 1H), 0.65-0.46 (m, 5H) ppm. ^13C NMR (CDCl3, 150 MHz): δ = 176.6, 156.2, 143.9, 143.8, 141.4, 127.9, 127.2, 125.2, 125.1 , 120.1, 67.3, 57.4, 47.3, 13.9, 3.4 ppm. HRMS (ESI): m/z [M + Na]^+ Calculated value C20H19NO4Na 360.1206, measured value 360.1193.
References
[1] Journal of the American Chemical Society, 2016, vol. 138, # 5, p. 1698 - 1708
[2] Patent: WO2016/138288, 2016, A1. Location in patent: Page/Page column 124
Fmoc-L-cyclopropylglycine Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Amatek Scientific Co. Ltd. | 0512-56316828 4008675858 | sales@amateksci.com | China | 9849 | 55 |
| Nanjing Becas pharmatech Ltd. | +86-13912903754 13912903754 | info@becaspharma.com | China | 3962 | 58 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| ShenZhen InnoSyn Biotech Co.,Ltd | 0755-28351685 18503098468 | innosyn@163.com | China | 602 | 55 |
| SINO High Goal Chemical Technology Co., Ltd. | 021-57646680 18306277365 | sunkai@chembiobanksh.com | China | 2039 | 55 |
| HBCChem, Inc. | +1-510-219-6317 | sales@hbcchem.com | United States | 10628 | 60 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Hangzhou J&H Chemical Co., Ltd. | 0571-87396432 | sales@jhechem.com | China | 14905 | 59 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66028182 17714375163 | yftan@aikonchem.com | China | 16674 | 50 |
