MENTHONE
- CAS No.
- 89-80-5
- Chemical Name:
- MENTHONE
- Synonyms
- P-MENTHAN-3-ONE;Cyclohexanone, 5-methyl-2-(1-methylethyl)-, trans-;2-Isopropyl-5-methylcyclohexanone;d-Menthone;p-Menthone;MENTHON;FEMA 2667;trans-Menthone;MENTHONE;MENTHON REIN
- CBNumber:
- CB6453271
- Molecular Formula:
- C10H18O
- Molecular Weight:
- 154.25
- MDL Number:
- MFCD00062998
- MOL File:
- 89-80-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 147-148 °C |
|---|---|
| Boiling point | 210°C |
| Density | 0.896 |
| vapor pressure | 37Pa at 25℃ |
| FEMA | 2667 | MENTHONE |
| refractive index | 1.450 |
| FLAVIS Number | 07.176 | trans-Menthone |
| Flash point | 69 ºC |
| storage temp. | Refrigerator |
| solubility | Chloroform (Sparingly), Methanol (Sparingly) |
| form | Oil |
| color | Colourless |
| Odor | at 10.00 % in dipropylene glycol. minty |
| Odor Type | minty |
| Viscosity | 18.559mm2/s |
| Water Solubility | 688mg/L at 25℃ |
| Henry's Law Constant | 5.7×10-2 mol/(m3Pa) at 25℃, Marin et al. (1999) |
| Cosmetics Ingredients Functions | PERFUMING |
| LogP | 2.295 at 25℃ |
| Substances Added to Food (formerly EAFUS) | MENTHONE |
| EWG's Food Scores | 1 |
| FDA UNII | 9NH5J4V8FN |
| NIST Chemistry Reference | Cyclohexanone, 5-methyl-2-(1-methylethyl)-, trans-(89-80-5) |
| EPA Substance Registry System | Cyclohexanone, 5-methyl-2-(1-methylethyl)-, (2R,5S)-rel- (89-80-5) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H412-H302 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P273-P501 |
| Hazard Codes | Xn |
| Risk Statements | 22-36-43-52/53 |
| Safety Statements | 26-36/37-61 |
| TSCA | TSCA listed |
| HS Code | 29142990 |
| Hazardous Substances Data | 89-80-5(Hazardous Substances Data) |
| Toxicity | The acute oral LD50 in rats was reported as 2.18 ml/kg (1.82-2.62 ml/kg) (Levenstein, 1973a). The acute dermal LD50 in rabbits exceeded 5 g/kg (Levenstein, 1973b) |
| REACH Registrations | Active |
MENTHONE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FM74368 | Menthone | 89-80-5 | 0.025g | $214.17 | 2026-06-04 | Buy |
| Biosynth | FM74368 | Menthone | 89-80-5 | 0.05g | $328.39 | 2026-06-04 | Buy |
| Biosynth | FM74368 | Menthone | 89-80-5 | 0.1g | $499.73 | 2026-06-04 | Buy |
| Biosynth | FM74368 | Menthone | 89-80-5 | 0.25g | $803.14 | 2026-06-04 | Buy |
| Biosynth | FM74368 | Menthone | 89-80-5 | 0.5g | $1070.85 | 2026-06-04 | Buy |
MENTHONE Chemical Properties,Uses,Production
Description
Menthone has a characteristic odor similar to menthol. May be prepared by oxidation of menthol.
Chemical Properties
Menthone has a characteristic mint-like odor.
Occurrence
Reported found in severalstereoisomersin nature; l-menthone is a constituent of the essential oils of Russian and American peppermint, geranium, Andropogon gragrans, Mentha timija and Mentha arvensis; d-menthone is present in the essential oils of Barosma pulchellum, Nepeta japonica Maxim., and others. d-Isomenthone has been reported isolated from Micromeria abis sinica Benth., Pelargonium tomentosum Jacquin and others; l-isomenthone has been identified in Réunion geranium, Pelargonium capitau and others. Also reported found in lemon peel oil, black currants, celery seed, cinnamon, peppermint, cornmint, pennyroyal and other mentha oils, nutmeg, thymus, cocoa, mushrooms, starfruit, coriander leaf, rice, tarragon, calamus, buckwheat, sweet and bitter fennel, cherimoya, buchu oil, clam and sweet grass oil.
Uses
(±)-Menthone is a Menthol derivative. A volatile flavor compound found in human milk, red and black rice bran and specialty rice types.
Preparation
By oxidation of menthol.
Definition
ChEBI: (-)-menthone is a menthone that is cyclohexanone substituted by a methyl and an isopropyl group at positions 5 and 2 respectively (the 2S,5R-stereoisomer). It is an enantiomer of a (+)-menthone.
Aroma threshold values
Detection: 170 ppb; aroma characteristics at 1.0%: minty, cooling, sweet, refreshing, peppermint fresh, slightly dirty woody, camphoraceous with a green herbal anise nuance.
Taste threshold values
Taste characteristics at 50 ppm: cooling, peppermint, fresh green, minty, herbal, dirty mentholic with a refreshing camphoraceous nuance.
Flammability and Explosibility
Not classified
Safety Profile
Moderately toxic by ingestion, intravenous, and subcutaneous routes. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes. See also KETONES.
Metabolism
Hmlinen (1912) claimed that menthone was probably oxidized in the rabbit to ketomenthone, since the glucuronide produced was converted by warm dilute H2SO4 to a substance which was probably △4(8 -p-menthen-3-one (pulegone). Williams (1940), however, showed that it underwent reduction in the rabbit with the production of d-neomenthol. The presence of l-menthol, the other possible reduction product, was not detected and it appeared that the biological reduction was asymmetric (Williams, 1959).
MENTHONE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| Cheng Du Pufeide Biotechnology Co., Ltd. | 028-82610909 13388174823 | scglp@glp-china.com | China | 1064 | 58 |
| Shanghai Aspire Biological Technology Co., Ltd. | 021-61317773 | sales@aspirebio.com | China | 2880 | 58 |
| Shanghai Macklin Biochemical Co.,Ltd. | 15221275939 15221275939 | shenlinxing@macklin.cn | China | 15775 | 55 |
| Shanghai Yongye Biotechnology Co., Ltd. | 86-021-61559134 15921386130 | 3423497944@qq.com | China | 8135 | 55 |
| Shanghai ChengShao Biological Technology Co., Ltd. | 021-61847300 13341622919 | shcss01@163.com | China | 4806 | 58 |
| Shanghai Yihe Biological Technology Co., Ltd. | 021-68882955 17721395025 | 2423903095@qq.com | China | 4999 | 58 |
| Aikon International Limited | 025-66113011 19370895928 | qzhang@aikonchem.com | China | 15390 | 58 |
| Shanghai Haohong Pharmaceutical Co., Ltd. | 400-8210725 400821072 | malulu@leyan.com | China | 24933 | 58 |
| Beijing OKA biological technology co., LTD | 010-62971590 18548936886 | 3462612863@qq.com | China | 10061 | 58 |
