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Adrenosterone

CAS No.
382-45-6
Chemical Name:
Adrenosterone
Synonyms
11-KETOANDROSTENEDIONE;ANDROST-4-ENE-3,11,17-TRIONE;Nsc12166;s substance G;ADRENOSTERONE;Andrenosterone;Reichstein'REICHSTEIN'S 'G';(+)-ADRENOSTERONE;Adrenosterone >
CBNumber:
CB1765508
Molecular Formula:
C19H24O3
Molecular Weight:
300.39
MDL Number:
MFCD00003606
MOL File:
382-45-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:15

Adrenosterone Properties

Melting point 219-222 °C(lit.)
alpha 300 º (c=1 in chloroform)
Boiling point 381.62°C (rough estimate)
Density 1.1381 (rough estimate)
refractive index 290 ° (C=0.2, EtOH)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Ethyl Acetate (Slightly)
form Solid
color White to Off-White
optical activity [α]20/D +300°, c = 1 in chloroform
Water Solubility 98.49mg/L(23.5 ºC)
Merck 14,176
InChIKey RZRPTBIGEANTGU-IRIMSJTPSA-N
CAS DataBase Reference 382-45-6(CAS DataBase Reference)
FDA UNII AE4E9102GY
NIST Chemistry Reference Androst-4-ene-3,11,17-trione(382-45-6)

SAFETY

Risk and Safety Statements

WGK Germany  3

Adrenosterone price More Price(39)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 284998 Adrenosterone 98% 382-45-6 5g $315 2026-04-30 Buy
TCI Chemical A1397 Adrenosterone >98.0%(HPLC) 382-45-6 1g $61 2021-12-16 Buy
TRC TRC-A305600-5G Adrenosterone 382-45-6 5g $182 2026-06-03 Buy
TRC TRC-A305600-50MG Adrenosterone 382-45-6 50mg $78 2026-06-03 Buy
TRC TRC-A305600-100MG Adrenosterone 382-45-6 100mg $92 2026-06-03 Buy
Product number Packaging Price Buy
284998 5g $315 Buy
A1397 1g $61 Buy
TRC-A305600-5G 5g $182 Buy
TRC-A305600-50MG 50mg $78 Buy
TRC-A305600-100MG 100mg $92 Buy

Adrenosterone Chemical Properties, Uses, Production

Chemical Properties

Off-White to Pale Yellow Solid

Uses

Androstenedione is a steroid hormone. It is used to make medicine. Androstenedione is used to increase the production of the hormone testosterone to enhance athletic performance, increase energy, keep red blood cells healthy, enhance recovery and growth from exercise, and increase sexual desire and performance.

Definition

ChEBI: Adrenosterone is a 3-oxo Delta(4)-steroid that is androst-4-ene carrying three oxo-substituents at positions 3, 11 and 17. It has a role as an androgen, a human urinary metabolite, a marine metabolite and an EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitor. It is a 3-oxo-Delta(4) steroid, a 17-oxo steroid, an androstanoid and an 11-oxo steroid. It derives from a hydride of an androstane.

benefits

Adrenosterone is sold as a dietary supplement since 2007 as a fat loss and muscle gaining supplement. It is thought to be a competitive selective 11βHSD1 inhibitor, which is responsible for activation of cortisol from cortisone. Thus preventing muscle breakdown, and contributing to a majority of its effects.

Purification Methods

Dissolve adrenosterone i n Me2CO, decolorise it with charcoal, filter, add H2O, Me2CO evaporate and the solid is recrystallised from aqueous EtOH. Also recrystallise it from Et2O or Et2O/pentane and dry it at 110o/0.1mm for 2hours. It can be sublimed under high vacuum. [Reichstein Helv Chim Acta 20 953, 979 1937, Mason et al. J Biol Chem 116 267 1936, Beilstein 7 III 4601.]

382-44-5
382-45-6
Synthesis of Adrenosterone from 11β-Hydroxyandrost-4-ene-3,17-dione

Adrenosterone Preparation Products And Raw materials

Global Suppliers ( 164)
Supplier Tel Email Country ProdList Advantage
Nanjing Shizhou Biotechnology Co., Ltd 025-0258556344 17301488900 rose.shi@synzest.com China 271 58
Smartchem(Beijing) Ltd. 010-57203829 15810312480@139.com China 50 55
Hunan Jiuwei Biopharmaceutical Co., Ltd 19176660800; 19176660800 alexybw@hnjwpharma.com China 22 58
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Beijing HwrkChemical Technology Co., Ltd 89508211 18501085097 sales.bj@hwrkchemical.com China 9409 55
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 45000 61
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
China DongFan Chemical Co.,LTD 86-0571-85151182 China 5681 66
skychemical Co.Ltd 021-20958197 20965099 sales@skychemical.com China 1182 57

View Latest Price from Adrenosterone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Adrenosterone pictures 2026-10-13 Adrenosterone
382-45-6
0.99 RongNa Biotechnology Co.,Ltd
Adrenosterone pictures 2026-10-10 Adrenosterone
382-45-6
$1.00 1KG 98% 20T Shaanxi Dideu Medichem Co. Ltd
Adrenosterone pictures 2025-08-22 Adrenosterone
382-45-6
$2150.00 99% 20 tons Dingwang Technology (Wuhan) Co., Ltd.
  • Adrenosterone pictures
  • Adrenosterone
    382-45-6
  • $2150.00
  • 99%
  • Dingwang Technology (Wuhan) Co., Ltd.
Nsc12166 ADRENOSTERONE (11-OXO) 11-Keto-4-androstene-3,17-dione 11-Oxo-4-androstene-3,17-dione 4-Androstene-3,11,17-trione Reichstein's Substance G Reichstein&apos s substance G (8S,9S,10R,13S,14S)-10,13-dimethyl-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,11,17-trione REICHSTEIN'S SUBSTANCE G REICHSTEIN'S SUBSTANCE 'G' REICHSTEIN'S ''G'' REICHSTEIN'S 'G' 11-Oxo/Adrenosterone sodium (6R,7R)-3-(acetyloxymethyl)-7-[(2-cyano-1-oxo-2-phenylethyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate (+)-ADRENOSTERONE Adrenosterone ((+)-Adrenosterone) 4-ANDROSTENE-3,11,17-TRIONE 4-ANDROSTEN-3,11,17-TRIONE ADRENOSTERONE 11-Oxy-4-androstenedione Adrenosterone;Androst-4-ene-3,11,17-trione;Reichstein's substance G 11-Ketoandrostenedione, 4-Androstene-3,11,17-trione, Androst-4-ene-3,11,17-trione, Reichsteins substance G (8β,9α,10β,14α,13β)-Androsta-4-ene-3,11,17-trione Andrenosterone 11-OXO Prohormones Adrenosterone Androsten-3,11,17-trione (Solution) Adrenosterone > Androsten-3,11,17-trione 11-oxoandrostenedione (8S,9S,10R,13S,14S)-10,13-Dimethyl-7,8,10,12,13,14,15,16-octahydro-1H-cyclopenta[a]phenanthrene-3,11,17(2H,6H,9H)-trione 11-Ketoandrostenedione-[2.3.4-13C3] Adrenosterone, 10 mM in DMSO 1-D,3,4-13C2-Adrenosterone 11-KETOANDROSTENEDIONE ANDROST-4-ENE-3,11,17-TRIONE 11-Ketoandrostenedione-[3,4-13C2, 1-d]/Adrenosterone-[3,4-13C2,1-d] 382-45-6 328-45-6 Steroids 17-Ketosteroids Chiral Building Blocks Asymmetric Synthesis Complex Molecules 17-Ketosteroids Biochemistry Pharmaceutical Intermediates Steroids Inhibitors Intermediates & Fine Chemicals Pharmaceuticals