5-Bromo-2-methyl-2-pentene
- CAS No.
- 2270-59-9
- Chemical Name:
- 5-Bromo-2-methyl-2-pentene
- Synonyms
- 5-BROMO-2-METHYLPENT-2-ENE;NSC 244464;Homoprenyl bromide;Prenylmethyl bromide;5-Bromo-2-methyl-2-pentene;2-Pentene,5-bromo-2-methyl-;5-bromo-2-methyl-2-pentylene;5-Bromo-2-methyl-2-pentene 97%;5-Bromo-2-methyl-2-pentene - [B0351];5-
Bromo- 2- methyl- 2- pentene
- CBNumber:
- CB6462772
- Molecular Formula:
- C6H11Br
- Molecular Weight:
- 163.06
- MDL Number:
- MFCD00009887
- MOL File:
- 2270-59-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | -102.35°C (estimate) |
|---|---|
| Boiling point | 152-154 °C (lit.) |
| Density | 1.217 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | 73 °F |
| storage temp. | 2-8°C |
| form | liquid |
| Specific Gravity | 1.217 |
| Appearance | Colorless to light yellow Liquid |
| Water Solubility | Slightly miscible with water. |
| BRN | 1735749 |
| InChI | InChI=1S/C6H11Br/c1-6(2)4-3-5-7/h4H,3,5H2,1-2H3 |
| InChIKey | UNXURIHDFUQNOC-UHFFFAOYSA-N |
| SMILES | C/C(/C)=C\CCBr |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H315-H319-H335 | |||||||||
| Precautionary statements | P210-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 10-36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| RIDADR | UN 1993 3/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10-23 | |||||||||
| Hazard Note | Irritant | |||||||||
| HazardClass | 3 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29033990 | |||||||||
| Storage Class | 3 - Flammable liquids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Flam. Liq. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| Limited Quantities | 1.0 L (0.3 gallon) (liquid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml) | |||||||||
| NFPA 704 |
|
5-Bromo-2-methyl-2-pentene price More Price(38)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 262501 | 5-Bromo-2-methyl-2-pentene 97% | 2270-59-9 | 1g | $93.3 | 2026-04-30 | Buy |
| Sigma-Aldrich | 262501 | 5-Bromo-2-methyl-2-pentene 97% | 2270-59-9 | 5g | $195.75 | 2026-04-30 | Buy |
| TCI Chemical | B6764 | 5-Bromo-2-methylpent-2-ene min. 98.0 % | 2270-59-9 | 1G | $36 | 2026-04-30 | Buy |
| TCI Chemical | B6764 | 5-Bromo-2-methylpent-2-ene min. 98.0 % | 2270-59-9 | 5G | $125 | 2026-04-30 | Buy |
| Apolloscientific | OR3008 | 5-Bromo-2-methylpent-2-ene >99% | 2270-59-9 | 250mg | $21 | 2026-06-04 | Buy |
5-Bromo-2-methyl-2-pentene Chemical Properties, Uses, Production
Uses
5-Bromo-2-methyl-2-pentene acts as a synthetic reagent, which is useful in the formation of sesqueterpenoid. It is also employed in the preparation of geranlol-3-14C. Further, it is used in the preparation of penifulvin A, which is a sesquiterpenoid with a novel dioxa-fenestrane structure.
Synthesis
765-43-5
75-16-1
2270-59-9
1. 105 kg of THF solution of 12% methylmagnesium bromide (equivalent to 12.6 kg 100% concentration) was slowly added to a stainless steel reactor under brine bath cooling, maintaining the reaction temperature at 30-35°C. 2. 6.7 kg of cyclopropyl methyl ketone (II) was added dropwise to the reactor. 2. 6.7 kg of cyclopropyl methyl ketone (II) was added dropwise to the reactor, and after completion of the dropwise addition, the reaction mixture was stirred continuously at 30-35 °C for at least 1 hour. 3. the reaction mixture was cooled to 5-10 °C and then transferred to another enameled reactor pre-cooled to 0-10 °C containing 60 kg of 35% sulfuric acid. 4. the reaction mixture was warmed to 25-30 °C and maintained at this temperature for at least 15 minutes to ensure complete reaction. Subsequently, it was left to fully separate the two phases and remove the lower aqueous phase. 5. The organic phase was washed with 6.7 kg of softened water, stirred at 25-30 °C and left to stratify, again removing the lower aqueous phase. 6. Remove the solvent from the organic phase by vacuum distillation until an oily residue is obtained. To the residue was added 10.1 kg of THF and stirred until complete dissolution. 7. The resulting solution was transferred to a vessel of suitable capacity and prepared for the next stage of the reaction. 8. 8. 10 kg of the target product 5-bromo-2-methyl-2-pentene was finally obtained in 77% yield based on cyclopropyl methyl ketone (II).
References
[1] Chemistry - A European Journal, 2009, vol. 15, # 40, p. 10473 - 10485
[2] Organic and Biomolecular Chemistry, 2014, vol. 12, # 47, p. 9707 - 9715
[3] Organic Letters, 2006, vol. 8, # 24, p. 5421 - 5424
[4] European Journal of Organic Chemistry, 2006, # 14, p. 3181 - 3192
[5] Patent: US2009/43093, 2009, A1. Location in patent: Page/Page column 3
5-Bromo-2-methyl-2-pentene Preparation Products And Raw materials
5-Bromo-2-methyl-2-pentene Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Tianjin Derchemist Science & Technology Co., Ltd. | 22-58627059 13920586291 | zdcomcon@126.com | China | 4093 | 50 |
| Hangzhou Lordaerun Medical Technology Co., LTD | 18968132030 | 414725184@qq.com | China | 171 | 58 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 45000 | 61 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16307 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shanghai Topbiochem Technology Co., Ltd | +86-21-60341587 | sales@topbiochem.com | China | 6166 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| ShangHai AmK Pharmaceutical Technology Co., Ltd. | 微信 18019252918 18019252918 | sale@amkchem.com | China | 14961 | 55 |
View Latest Price from 5-Bromo-2-methyl-2-pentene manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | 5-Bromo-2-methyl-2-pentene
2270-59-9
|
$5.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-06-30 | 5-BROMO-2-METHYL-2-PENTENE
2270-59-9
|
1kg | 99% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2025-12-24 | 5-Bromo-2-methyl-2-pentene
2270-59-9
|
1KG | 99.0% | 1000 tons | Shaanxi Dideu Medichem Co. Ltd |
-
- 5-Bromo-2-methyl-2-pentene
2270-59-9
- $5.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 5-BROMO-2-METHYL-2-PENTENE
2270-59-9
- $0.00
- 99%
- Shaanxi Dideu New Materials Co. Ltd
-
- 5-Bromo-2-methyl-2-pentene
2270-59-9
- $0.10
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
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