MS0124
- CAS No.
- 1197196-63-6
- Chemical Name:
- MS0124
- Synonyms
- MS0124;MS0124, 10 mM in DMSO;4-Quinazolinamine, 6,7-dimethoxy-N-(1-methyl-4-piperidinyl)-2-(4-morpholinyl)-
- CBNumber:
- CB64668237
- Molecular Formula:
- C20H29N5O3
- Molecular Weight:
- 387.48
- MDL Number:
- MOL File:
- 1197196-63-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
MS0124 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0078017 | MS0124 99.79% | 1197196-63-6 | 5mg | $162 | 2026-06-04 | Buy |
| ChemScene | CS-0078017 | MS0124 99.79% | 1197196-63-6 | 10mg | $271 | 2026-06-04 | Buy |
| ChemScene | CS-0078017 | MS0124 99.79% | 1197196-63-6 | 25mg | $542 | 2026-06-04 | Buy |
| ChemScene | CS-0078017 | MS0124 99.79% | 1197196-63-6 | 50mg | $867 | 2026-06-04 | Buy |
| Axon Medchem | Axon4338 | MS0124 | 10mg | $132 | 2026-05-19 | Buy |
MS0124 Chemical Properties, Uses, Production
Description
MS0124 is a Potent and Selective Inhibitors for G9a-Like Protein (GLP) Lysine Methyltransferase. MS0124 was 34-fold more selective for GLP (IC50 =_x000D_ 13 ± 4 nM) over G9a (IC50 = 440 ± 63 nM). G9a-like protein (GLP) and G9a are highly homologous protein lysine methyltransferases (PKMTs) sharing approximately 80% sequence identity in their catalytic domains. GLP and G9a form a heterodimer complex and catalyze mono- and dimethylation of histone H3 lysine 9 and nonhistone substrates
Uses
MS0124 is a potent selective G9a-like protein (GLP) inhibitor with IC50 values of 13±4 nM and 440±63 nM for GLP and G9a,respectively[1].
References
[1] Yan Xiong, et al. Structure-activity relationship studies of G9a-like protein (GLP) inhibitors. Bioorg Med Chem DOI:10.1016/j.bmc.2017.06.021
MS0124 Preparation Products And Raw materials
Raw materials
Preparation Products
MS0124 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Beckham Medical Technology Co., Ltd | 13816613772 | huahero21@sina.com | China | 2994 | 55 |
| Shanghai SuperLan Chemcial Technique Centre | 0-2022843681 15618226720 | chaolaichem@foxmail.com | China | 9996 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6288 | 58 |
| Jinan Jiuli Biotechnology Co. , Ltd. | 15865264761 | 486064515@qq.com | China | 5000 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| Beijing Boorsen Biotechnology Co., Ltd | 400-901-9800 18611424007 | cis@bioss.com.cn | China | 9185 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 15850508050 | cindy.huang@synzest.com | China | 11975 | 58 |
| RD International Technology Co., Limited | 18024082417 | market@ubiochem.com | China | 9831 | 58 |
