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ChemicalBook CAS DataBase List MS0124
1197196-63-6

MS0124 synthesis

3synthesis methods
110-91-8 Synthesis
Morpholine

110-91-8
684 suppliers
$9.00/1g

4-Quinazolinamine, 2-chloro-6,7-dimethoxy-N-(1-methyl-4-piperidinyl)-

1197196-66-9
1 suppliers
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MS0124

1197196-63-6
17 suppliers
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Yield:1197196-63-6 81%

Reaction Conditions:

with hydrogenchloride in 1,4-dioxane;isopropyl alcohol at 160;Microwave irradiation;

References:

Liu, Feng;Chen, Xin;Allali-Hassani, Abdellah;Quinn, Amy M.;Wasney, Gregory A.;Dong, Aiping;Barsyte, Dalia;Kozieradzki, Ivona;Senisterra, Guillermo;Chau, Irene;Siarheyeva, Alena;Kireev, Dmitri B.;Jadhav, Ajit;Herold, J. Martin;Frye, Stephen V.;Arrowsmith, Cheryl H.;Brown, Peter J.;Simeonov, Anton;Vedadi, Masoud;Jin, Jian [Journal of Medicinal Chemistry,2009,vol. 52,# 24,p. 7950 - 7953] Location in patent:supporting information; experimental part

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