ChemicalBook >> CAS DataBase List >>2-Chloro-1,3,2-dioxaphospholane

2-Chloro-1,3,2-dioxaphospholane

2-Chloro-1,3,2-dioxaphospholane structure

CAS No.: 822-39-9

Chemical Name:: 2-Chloro-1,3,2-dioxaphospholane

Synonyms: AURORA KA-1222;Ethyl chlorphosphite;ETHYLENE CHLOROPHOSPHITE;Ethylenechlorophosphite,97%;Ethylenephosphorochloridite;ETHYLENE CYCL-CHLOROPHOSPHITE;2-dioxaphospholane,2-chloro-3;ETHYLENE CYCLO-CHLOROPHOSPHITE;2-CHLORO-1,3,2-DIOXAPHOSPHOLANE;Ethylene glycol chlorophosphite

CBNumber:: CB6494609

Molecular Formula:: C2H4ClO2P

Molecular Weight:: 126.48

MDL Number:: MFCD00014511

MOL File:: 822-39-9.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 05:23:23

Request For Quotation

2-Chloro-1,3,2-dioxaphospholane Properties

Melting point	-28°C(lit.)
Boiling point	62 °C/20 mmHg (lit.)
Density	1.422 g/mL at 25 °C (lit.)
refractive index	n20/D 1.489(lit.)
Flash point	158 °F
storage temp.	2-8°C
solubility	Chloroform (Slightly)
form	clear liquid
color	Colorless to Light yellow
Sensitive	Moisture Sensitive
BRN	506179
Stability	Extremely Moisture Sensitive
InChI	1S/C2H4ClO2P/c3-6-4-1-2-5-6/h1-2H2
InChIKey	OLSFRDLMFAOSIA-UHFFFAOYSA-N
SMILES	ClP1OCCO1
CAS DataBase Reference	822-39-9(CAS DataBase Reference)
NIST Chemistry Reference	Ethylene chlorophosphite(822-39-9)
EPA Substance Registry System	1,3,2-Dioxaphospholane, 2-chloro- (822-39-9)
UNSPSC Code	12352005
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05,GHS07

Signal word

Danger

Hazard statements

H314-H335

Precautionary statements

P261-P271-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338

target organs

Respiratory system

PPE

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Hazard Codes

Risk Statements

14-34-37

Safety Statements

26-36/37/39-45-8-25

RIDADR

UN 3264 8/PG 2

WGK Germany

1-10

Hazard Note

Highly reactive cyclic phosphitylating reagent which

TSCA

TSCA listed

HS Code

2934.99.9001

HazardClass

PackingGroup

Storage Class

8A - Combustible corrosive hazardous materials

Hazard Classifications

Skin Corr. 1B
STOT SE 3

NFPA 704

	2
3		0
	W

2-Chloro-1,3,2-dioxaphospholane price More Price(21)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	391220	2-Chloro-1,3,2-dioxaphospholane 97%	822-39-9	5ml	$178	2026-04-30	Buy
TCI Chemical	C1215	2-Chloro-1,3,2-dioxaphospholane >97.0%(GC)	822-39-9	5g	$37	2026-04-30	Buy
TCI Chemical	C1215	2-Chloro-1,3,2-dioxaphospholane >97.0%(GC)	822-39-9	25g	$109	2026-04-30	Buy
Usbiological	C4979-85	2-Chloro-1,3,2-dioxaphospholane		10g	$403	2026-06-03	Buy
TRC	TRC-C365500-5G	2-Chloro-1,3,2-dioxaphospholane	822-39-9	5g	$84	2026-06-03	Buy

Product number	Packaging	Price	Buy
391220	5ml	$178	Buy
C1215	5g	$37	Buy
C1215	25g	$109	Buy
C4979-85	10g	$403	Buy
TRC-C365500-5G	5g	$84	Buy

2-Chloro-1,3,2-dioxaphospholane Chemical Properties, Uses, Production

Chemical Properties

Clear Colourless Oil

Uses

Highly reactive cyclic phosphitylating reagent which provides fast coupling rates, and hydrolytic cleavage occurs more readily than with acyclic analogs

Uses

Ethylene chlorophosphite acts as a phosphitylating agent involved in the preparation of phosphocholine and spirophosphoranes. For example, it is used in the phosphorylation of p-tert-butyl(thia)calixarenes.

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: ligand

2-Chloro-1,3,2-dioxaphospholane Preparation Products And Raw materials

Raw materials

Preparation Products

2-Chloro-1,3,2-dioxaphospholane-2-oxide

2-Chloro-1,3,2-dioxaphospholane Suppliers

Global Suppliers ( 130)

Supplier	Tel	Email	Country	ProdList	Advantage
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15813	69
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
shanghai science Bio-Pharmceutical.co,ltd.	021-021-57872719 13761402923	245662540@qq.com	China	299	60
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32273	50
Syntechem Co.,Ltd		info@syntechem.com	China	12973	57

Supplier	Advantage
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
3B Pharmachem (Wuhan) International Co.,Ltd.	69
Alfa Aesar	84
TCI (Shanghai) Development Co., Ltd.	81
Energy Chemical	61
shanghai science Bio-Pharmceutical.co,ltd.	60
Shanghai Hanhong Scientific Co.,Ltd.	64
Chemsky（shanghai）International Co.,Ltd.	50
Syntechem Co.,Ltd	57

2-Chloro-1,3,2-dioxaphospholane Spectrum

2-Chloro-1,3,2-dioxaphospholane(822-39-9)MS 2-Chloro-1,3,2-dioxaphospholane(822-39-9)¹HNMR 2-Chloro-1,3,2-dioxaphospholane(822-39-9)¹³CNMR 2-Chloro-1,3,2-dioxaphospholane(822-39-9)Raman 2-Chloro-1,3,2-dioxaphospholane(822-39-9)IR 2-Chloro-1,3,2-dioxaphospholane(822-39-9)FT-IR

822-39-9 (2-Chloro-1,3,2-dioxaphospholane) Related Search:

Vinyl acetate Cyclopentane Bromocyclopentane Vinylene carbonate VINYL CHLORIDE

Methylcyclopentane Diethylene glycol Epichlorohydrin Ethylene glycol diacetate ETHYLENE

Ethylene carbonate Cyclopentyl chloride Dimethyl phosphite 1,2-Dibromoethane Ethylene glycol

Ethylene oxide Ethylene diacrylate Poly(ethylene)

1of4

1,3,2-Dioxaphospholane, 2-chloro- 1,3,2-Dioxaphosphorane.2-chloro- 2-dioxaphospholane,2-chloro-3 Ethylenephosphorochloridite AURORA KA-1222 ETHYLENE CYCL-CHLOROPHOSPHITE ETHYLENE CYCLO-CHLOROPHOSPHITE ETHYLENE CHLOROPHOSPHITE 2-CHLORO-1,3,2-DIOXAPHOSPHOLANE Ethylenechlorophosphite,97% 2-Chloro-1,3,2-dioxaphospholane,97% Ethylene phosphorochloridite（2-chloro-1,3,2-dioxaphospholane) Ethylene glycol chlorophosphite Cyclic O,O-Ethylene Phosphorochloridite Cyclic Phosphorochloridite Ethylene Glycol Phosphorochloridous Acid Cyclic Ethylene Ester Cyclic ethylene chlorophosphite Cyclic ethylene phosphorochloridite 2-Chloro-1,3,2-dioxaphospholane 97% 2-Chloro-1,3,2-dioxaphospholane > Ethyl chlorphosphite 822-39-9 C2H4ClO2P Phosphorus Compounds Phosphorus Precursors Catalysis and Inorganic Chemistry Phosphorylating Agents DNA / RNA Synthesis Phosphorylation Biochemistry Nucleosides, Nucleotides & Related Reagents Phosphorylating and Phosphorothioating Agents Phosphorylation Protecting Agents, Phosphorylating Agents & Condensing Agents Synthetic Organic Chemistry Phosphorylating and Phosphitylating Agents