ATRACTYLON
- CAS No.
- 6989-21-5
- Chemical Name:
- ATRACTYLON
- Synonyms
- (4aS,8aR)-3,8a-diMethyl-5-Methylene-4,4a,5,6,7,8,8a,9-octahydronaphtho[2,3-b]furan;Atractyline;ATRACTYLON;ATRACTYLINE(DISCONTINUED)(SH);(4aS)-4,4aα,5,6,7,8,8a,9-Octahydro-3,8aβ-dimethyl-5-methylenenaphtho[2,3-b]furan;(4aS,8aR)-4,4a,5,6,7,8,8a,9-Octahydro-3,8a-dimethyl-5-methylene-naphtho[2,3-b]furan;Naphtho[2,3-b]furan, 4,4a,5,6,7,8,8a,9-octahydro-3,8a-diMethyl-5-Methylene-, (4aS,8aR)-
- CBNumber:
- CB6500946
- Molecular Formula:
- C15H20O
- Molecular Weight:
- 216.32
- MDL Number:
- MFCD00210477
- MOL File:
- 6989-21-5.mol
- MSDS File:
- SDS
| Melting point | 61-63℃ |
|---|---|
| Boiling point | 287.1±19.0℃ (760 Torr) |
| Density | 1.02±0.1 g/cm3 (20 ºC 760 Torr) |
| Flash point | 121.7±8.3℃ |
| storage temp. | 2-8°C |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | Soild |
| color | Faint red to very dark red |
| InChI | InChI=1S/C15H20O/c1-10-5-4-6-15(3)8-14-12(7-13(10)15)11(2)9-16-14/h9,13H,1,4-8H2,2-3H3/t13-,15+/m0/s1 |
| InChIKey | TYPSVDGIQAOBAD-DZGCQCFKSA-N |
| SMILES | O1C=C(C)C2C[C@]3([H])[C@@](C)(CC1=2)CCCC3=C |
| LogP | 5.570 |
| UNSPSC Code | 12352200 |
ATRACTYLON price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML3510 | Atractylon ≥85% (HPLC) | 6989-21-5 | 5MG | $87.2 | 2023-06-20 | Buy |
| Sigma-Aldrich | SML3510 | Atractylon ≥85% (HPLC) | 6989-21-5 | 25MG | $351 | 2023-06-20 | Buy |
| Cayman Chemical | 37568 | Atractylon ≥95% | 6989-21-5 | 5mg | $43 | 2026-04-30 | Buy |
| Cayman Chemical | 37568 | Atractylon ≥95% | 6989-21-5 | 10mg | $77 | 2026-04-30 | Buy |
| Cayman Chemical | 37568 | Atractylon ≥95% | 6989-21-5 | 25mg | $172 | 2026-04-30 | Buy |
ATRACTYLON Chemical Properties,Uses,Production
Chemical Properties
Yellow liquid, soluble in organic solvents such as methanol, ethanol, DMSO, etc., derived from Atractylodes macrocephala and Atractylodes lancea.
Uses
Atractylone (Atractylon) is a sesquiterpenoid extracted from Atractylodis Rhizoma. Atractylone (Atractylon) alleviates influenza A virus (IAV)-induced lung injury via regulating the TLR7 signaling pathway, and acts as a promising agent for IAV treatment. Atractylone (Atractylon) inhibits the degranulation of mast cell and exhibits potential for the treatment of mast cell-mediated allergic reactions[1][2].
Definition
ChEBI: Atractylone is a sesquiterpenoid.
Biological Activity
Atractylon is a main active component of Atractylodis Rhizoma th at exhibits antibacterial, antiviral, anti-inflammatory, anti-allergic, anticancer, gastroprotective and neuroprotective activities. Atractylon inhibits proliferation, induces apoptosis and blocks invasion in varies hepatic cancer cell lines. It inhibits the expression of Bcl-2 and promotes the expression of Bax.
target
IL Receptor | VEGFR | Histamine Receptor
References
[1] Cheng Y, et al. Antiviral activities of atractylon from Atractylodis Rhizoma. Mol Med Rep. 2016 Oct;14(4):3704-10. DOI:10.3892/mmr.2016.5713
[2] Han NR, et al. Inhibitory effects of atractylone on mast cell-mediated allergic reactions. Chem Biol Interact. 2016 Oct 25;258:59-68. DOI:10.1016/j.cbi.2016.08.015
ATRACTYLON Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Moqi Biological Technology Co., LTD | 13341702378 | 190129269@qq.com | China | 9998 | 58 |
| Dalian Meilun Biotech Co., Ltd. | 0411-62910999 13889544652 | sales@meilune.com | China | 4765 | 58 |
| ShangHai YuanYe Biotechnology Co., Ltd. | 15026964105 | shyysw007@163.com | China | 4998 | 60 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-028-82633397 18982077548 | cwb1@biopurify.cn | China | 2376 | 60 |
| Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 | info@sagechem.com | China | 10265 | 58 |
| Shanghai Tauto Biotech Co., Ltd. | 021-51320588 | tauto@tautobiotech.com | China | 3984 | 66 |
| TargetMol Chemicals Inc. | 021-021-33632979 15002134094 | marketing@targetmol.com | China | 7993 | 58 |
| Cheng Du Pufeide Biotechnology Co., Ltd. | 028-82610909 13388174823 | scglp@glp-china.com | China | 1064 | 58 |
| Chengdu Herbpurify Co.Ltd. | 2355253622; 18981954830 | 2355253622@qq.com; | China | 1089 | 58 |
| Shanghai JONLN Reagent Co., Ltd. | 400-0066400 13621662912 | 422131432@qq.com | China | 9970 | 55 |
View Lastest Price from ATRACTYLON manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-02-24 | Atractylon
6989-21-5
|
20mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | ||
 |
2020-01-10 | ATRACTYLINE(DISCONTINUED)(SH)
6989-21-5
|
$9.80 | 1KG | ≥98% | 20 tons | Career Henan Chemical Co |
-
- Atractylon
6989-21-5
- $0.00
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
-
- ATRACTYLINE(DISCONTINUED)(SH)
6989-21-5
- $9.80
- ≥98%
- Career Henan Chemical Co
