2-Methoxy-N-methylbenzylamine 97
- CAS No.
- 6851-80-5
- Chemical Name:
- 2-Methoxy-N-methylbenzylamine 97
- Synonyms
- 2-METHOXY-N-METHYLBE;(2-methoxybenzyl)methylamine;2-Methoxy-N-methylbenzylamine;N-methyl-o-methoxybenzylamine;(2-methoxybenzyl)-methyl-amine;2-Methoxy-N-methylbenzylamine 97%;N-(2-METHOXYBENZYL)-N-METHYLAMINE;2-Methoxy-N-methylbenzylamine 97;2-Methoxy-N-methylbenzenemethanamine;2-Methoxy-N-methylbenzylamine
- CBNumber:
- CB6505204
- Molecular Formula:
- C9H13NO
- Molecular Weight:
- 151.21
- MDL Number:
- MFCD00025755
- MOL File:
- 6851-80-5.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H315-H318-H335 | |||||||||
| Precautionary statements | P280-P301+P312+P330-P302+P352-P305+P351+P338+P310 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-37/38-41 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | 8 | |||||||||
| HS Code | 2922290090 | |||||||||
| NFPA 704 |
|
2-Methoxy-N-methylbenzylamine 97 price More Price(52)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 593958 | 2-Methoxy-N-methylbenzylamine 97% | 6851-80-5 | 1g | $62.3 | 2023-01-07 | Buy |
| Sigma-Aldrich | 593958 | 2-Methoxy-N-methylbenzylamine 97% | 6851-80-5 | 5g | $202 | 2023-01-07 | Buy |
| Apolloscientific | OR925436 | 2-Methoxy-N-methylbenzylamine >98% | 6851-80-5 | 1g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR925436 | 2-Methoxy-N-methylbenzylamine >98% | 6851-80-5 | 5g | $59 | 2026-06-04 | Buy |
| Apolloscientific | OR925436 | 2-Methoxy-N-methylbenzylamine >98% | 6851-80-5 | 25g | $283 | 2026-06-04 | Buy |
2-Methoxy-N-methylbenzylamine 97 Chemical Properties, Uses, Production
Synthesis
135-02-4
74-89-5
6851-80-5
Step A: 2-methoxybenzaldehyde (5.56 g, 40 mmol) was dissolved in methanol (40 mL) and methylamine (40 wt% aqueous solution, 6.9 mL, 80 mmol) and acetic acid (240 mg, 4 mmol) were added sequentially. The reaction mixture was stirred at room temperature for 16 h and then cooled in an ice bath. Sodium borohydride (1.51 g, 40 mmol) was added in batches under ice bath cooling conditions. After addition, the reaction mixture was continued to stir at room temperature for 3 hours. After completion of the reaction, most of the solvent was removed by concentration under reduced pressure. The residue was diluted with distilled water (100 mL) and ethyl acetate (100 mL) and partitioned. The aqueous phase was extracted with ethyl acetate (2 × 100 mL) and the organic phases were combined. The organic phase was washed sequentially with saturated brine, dried over anhydrous sodium sulfate, and concentrated under reduced pressure to afford the target product N-methyl-2-methoxybenzylamine (4.7 g, 79% yield). The product was characterized by 1H NMR (CDCl3, 500 MHz): δ 7.23 (d, J = 7.4 Hz, 2H), 6.91 (t, J = 7.4 Hz, 1H), 6.86 (d, J = 7.9 Hz, 1H), 3.83 (s, 3H), 3.75 (s, 2H), 2.42 (s, 3H); ESI MS m/z = 152 [M + H]+. The crude product obtained can be used directly in the subsequent reaction without further purification.
References
[1] Patent: US2006/52378, 2006, A1. Location in patent: Page/Page column 144
[2] Bioorganic and Medicinal Chemistry Letters, 2016, vol. 26, # 10, p. 2539 - 2543
[3] Journal of the American Chemical Society, 1944, vol. 66, p. 1875,1879
[4] European Journal of Medicinal Chemistry, 2014, vol. 76, p. 314 - 331
[5] Bioorganic and Medicinal Chemistry, 2015, vol. 23, # 5, p. 911 - 923
2-Methoxy-N-methylbenzylamine 97 Preparation Products And Raw materials
Raw materials
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Preparation Products
2-Methoxy-N-methylbenzylamine 97 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| Tianjin heowns Biochemical Technology Co., Ltd. | 400 638 7771 | sales@heowns.com | China | 14412 | 57 |
| Sci General Material & Chemical Ltd | 021-58388037;21-58388037 13472507714 | 35177634@qq.com;1589045147@qq.com | China | 795 | 55 |
| Shenyang Yuancheng Pharmaceutical Technology Co., Ltd. | 024-31298370 15040047923 | yuanchengchem@163.com | China | 252 | 52 |
| Shanghai Litong Chemical Technology Co.,Ltd. | 13598610367 0373-7129549 | 2468833170@qq.com | China | 932 | 58 |
| Amatek Scientific Co. Ltd. | 0512-56316828 4008675858 | sales@amateksci.com | China | 9848 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
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