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Homo-PROTAC cereblon degrader 1

Homo-PROTAC cereblon degrader 1 Structure
Homo-PROTAC cereblon degrader 1 structure
CAS No.
2244520-98-5
Chemical Name:
Homo-PROTAC cereblon degrader 1
Synonyms
CRBN PROTAC compound I;Homo-PROTAC cereblon degrader 1;Homo-PROTAC cereblon degrader 1 ，S2881;1H-Isoindole-1,3(2H)-dione, 4,4′-[1,2-ethanediylbis(oxy-2,1-ethanediylimino)]bis[2-(2,6-dioxo-3-piperidinyl)-;Homo-PROTAC cereblon degrader 1,PROTACs,Inhibitor,inhibit,HomoPROTAC cereblon degrader 1,Homo PROTAC cereblon degrader 1;4,4'-(((Ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl))bis(azanediyl))bis(2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione);2-(2,6-dioxopiperidin-3-yl)-4-({2-[2-(2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}ethoxy)ethoxy]ethyl}amino)-2,3-dihydro-1H-isoindole-1,3-dione
CBNumber:
CB65848830
Molecular Formula:
C32H32N6O10
Molecular Weight:
660.64
MDL Number:
MFCD31813818
MOL File:
2244520-98-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-16 07:06:08
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Homo-PROTAC cereblon degrader 1 Properties

Boiling point 978.5±65.0 °C(Predicted)
Density 1.527±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: 200 mg/mL (302.74 mM)
pka 10.44±0.40(Predicted)
form Solid
color Light yellow to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

Homo-PROTAC cereblon degrader 1 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0087832 Homo-PROTAC cereblon degrader 1 ≥98% 2244520-98-5 1mg $62 2026-06-04 Buy
ChemScene CS-0087832 Homo-PROTAC cereblon degrader 1 ≥98% 2244520-98-5 5mg $140 2026-06-04 Buy
ChemScene CS-0087832 Homo-PROTAC cereblon degrader 1 ≥98% 2244520-98-5 10mg $241 2026-06-04 Buy
ChemScene CS-0087832 Homo-PROTAC cereblon degrader 1 ≥98% 2244520-98-5 25mg $367 2026-06-04 Buy
ChemScene CS-0087832 Homo-PROTAC cereblon degrader 1 ≥98% 2244520-98-5 50mg $588 2026-06-04 Buy
Product number Packaging Price Buy
CS-0087832 1mg $62 Buy
CS-0087832 5mg $140 Buy
CS-0087832 10mg $241 Buy
CS-0087832 25mg $367 Buy
CS-0087832 50mg $588 Buy

Homo-PROTAC cereblon degrader 1 Chemical Properties, Uses, Production

Description

Homo-PROTAC Cereblon Degrader 1 is a highly potent and efficient Cereblon (CRBN) degrader with minimal effects on IKZF1 and IKZF3.

Uses

Homo-PROTAC cereblon degrader 1 (compound 15a) is a highly potent and efficient Cereblon (CRBN) degrader with only minimal effects on IKZF1 and IKZF3[1].

IC 50

Cereblon

References

[1] Steinebach C, et al. Homo-PROTACs for the Chemical Knockdown of Cereblon. ACS Chem Biol. 2018 Sep 21;13(9):2771-2782. DOI:10.1021/acschembio.8b00693

Homo-PROTAC cereblon degrader 1 Preparation Products And Raw materials

Raw materials

Preparation Products

Homo-PROTAC cereblon degrader 1 Suppliers

Global Suppliers ( 45)
Supplier Tel Email Country ProdList Advantage
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Shanghai Chaolan Chemical Technology Center QQ：65489617 13301690235 Sales@ATKchemical.com China 9711 58
Beijing Solarbio Science & Tecnology Co., Ltd. 17801761073 18101056239 3193328036@qq.com China 28150 68
Aikon International Limited 025-66061636 19370895928 qqyang@aikonchem.com China 15810 58
Shanghai Jizhi Biochemical Technology Co. Ltd. 021-4009004166/18616739031 18616739031 3007523370@qq.com China 40000 58
Jilin Province Woda Biotechnology Co., Ltd. 13504435624 1927928688@qq.com China 1644 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
InvivoChem +1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6378 58
Henan Weituxi Chemical Technology Co., Ltd. 0371-63284658 18135795563 3905209149@qq.com China 9705 58
Supplier Advantage
Shanghai EFE Biological Technology Co., Ltd. 58
Shanghai YuanYe Biotechnology Co., Ltd. 60
Shanghai Chaolan Chemical Technology Center 58
Beijing Solarbio Science & Tecnology Co., Ltd. 68
Aikon International Limited 58
Shanghai Jizhi Biochemical Technology Co. Ltd. 58
Jilin Province Woda Biotechnology Co., Ltd. 58
TargetMol Chemicals Inc. 58
InvivoChem 58
Henan Weituxi Chemical Technology Co., Ltd. 58

View Latest Price from Homo-PROTAC cereblon degrader 1 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Homo-PROTAC cereblon degrader 1 pictures 2026-07-15 Homo-PROTAC cereblon degrader 1
2244520-98-5
 $71.00-297.00 98.30% 10g TargetMol Chemicals Inc.
Homo-PROTAC cereblon degrader 1 pictures 2026-07-15 Homo-PROTAC cereblon degrader 1
2244520-98-5
 $71.00-297.00 98.30% 10g TargetMol Chemicals Inc.

Homo-PROTAC cereblon degrader 1 Spectrum

Homo-PROTAC cereblon degrader 1(2244520-98-5)1HNMR

2244520-98-5 (Homo-PROTAC cereblon degrader 1) Related Search:

Homo-PROTAC pVHL30 degrader 1 Halo PROTAC 1 1H-Isoindole-1,3(2H)-dione, 4-[(6-aminohexyl)amino]-2-(1-methyl-2,6-dioxo-3-piperidinyl)- 4-((2-(2-(2-(2-(4-aminophenoxy)ethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Thalidomide-NH-PEG2-C2-NH2 hydrochloride
Pomalidomide-PEG3-N3

1of2

Homo-PROTAC cereblon degrader 1 4,4'-(((Ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl))bis(azanediyl))bis(2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione) Homo-PROTAC cereblon degrader 1,PROTACs,Inhibitor,inhibit,HomoPROTAC cereblon degrader 1,Homo PROTAC cereblon degrader 1 2-(2,6-dioxopiperidin-3-yl)-4-({2-[2-(2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}ethoxy)ethoxy]ethyl}amino)-2,3-dihydro-1H-isoindole-1,3-dione Homo-PROTAC cereblon degrader 1 ，S2881 1H-Isoindole-1,3(2H)-dione, 4,4′-[1,2-ethanediylbis(oxy-2,1-ethanediylimino)]bis[2-(2,6-dioxo-3-piperidinyl)- CRBN PROTAC compound I 2244520-98-5 C32H32N6O10