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Diethyl 2,2-diethoxyethylphosphonate

Diethyl 2,2-diethoxyethylphosphonate structure

CAS No.: 7598-61-0

Chemical Name:: Diethyl 2,2-diethoxyethylphosphonate

Synonyms: NSC 77101;NSC 407851;AURORA KA-1450;LABOTEST-BB LT01148150;Diethyl 2,2-diethoxyethyl;DIETHYL 2,2-DIETHOXETHYLPHOSPHONATE;DIETHYL-2,2-DIETHOXYETHYLPHOSPONATE;Diethyl 2,2-diethoxyethylphosphonate;DIETHYL 2,2-DIETHOXY-ETHANEPHOSPHONATE;Diethyl2,2-Diethoxyethylphosphonate>

CBNumber:: CB6669966

Molecular Formula:: C10H23O5P

Molecular Weight:: 254.26

MDL Number:: MFCD00009236

MOL File:: 7598-61-0.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-09-12 18:54:21

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Diethyl 2,2-diethoxyethylphosphonate Properties

Boiling point	146-149 °C14 mm Hg(lit.)
Density	1.052 g/mL at 25 °C(lit.)
refractive index	n20/D 1.430(lit.)
Flash point	>230 °F
storage temp.	2-8°C
solubility	Chloroform, Dichloromethane
form	Oil
color	Colourless
Water Solubility	Soluble in chloroform and dichloromethane. Not miscible or difficult to mix in water.
Sensitive	Moisture Sensitive
BRN	1785614
InChI	1S/C10H23O5P/c1-5-12-10(13-6-2)9-16(11,14-7-3)15-8-4/h10H,5-9H2,1-4H3
InChIKey	LUQYELQXRPNKRY-UHFFFAOYSA-N
SMILES	CCOC(CP(=O)(OCC)OCC)OCC
CAS DataBase Reference	7598-61-0(CAS DataBase Reference)
FDA UNII	KS6N6SP2MG
UNSPSC Code	12352108
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

target organs

Respiratory system

PPE

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-37/39

RIDADR

UN2810

WGK Germany

HazardClass

6.1

HS Code

29319090

Storage Class

10 - Combustible liquids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

Limited Quantities

5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)

Excepted Quantities

Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

NFPA 704

	1
2		1

Diethyl 2,2-diethoxyethylphosphonate price More Price(37)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	D99250	Diethyl 2,2-diethoxyethylphosphonate 95%	7598-61-0	25g	$258	2026-04-30	Buy
TCI Chemical	D2423	Diethyl 2,2-Diethoxyethylphosphonate >96.0%(GC)	7598-61-0	5g	$94	2026-04-30	Buy
TCI Chemical	D2423	Diethyl 2,2-Diethoxyethylphosphonate >96.0%(GC)	7598-61-0	25g	$272	2026-04-30	Buy
Usbiological	D3550-85	Diethyl 2,2-Diethoxethylphosphonate		10g	$355	2026-06-03	Buy
TRC	TRC-D444210-5G	Diethyl 2,2-Diethoxethylphosphonate	7598-61-0	5g	$91	2026-06-03	Buy

Product number	Packaging	Price	Buy
D99250	25g	$258	Buy
D2423	5g	$94	Buy
D2423	25g	$272	Buy
D3550-85	10g	$355	Buy
TRC-D444210-5G	5g	$91	Buy

Diethyl 2,2-diethoxyethylphosphonate Chemical Properties, Uses, Production

Chemical Properties

Colourless Oil

Uses

Diethyl 2,2-diethoxyethylphosphonate can be used as a useful wittig reagent.

Uses

Diethyl 2,2-diethoxyethylphosphonate is used reactant for synthesis of α,β-alkenal derivatives by two-carbon homologation, lower rim-phosphonylated rexorcinol calix[4]arenes by condensation reactions, α-Phosphovinyl radicals via a radical trapping sequence, inhibitors of reverse transcriptase via 1,3-dipolar cycloadditions and for Friedel-Crafts reactions.

Uses

Reactant for synthesis of:

α,β-Alkenal derivatives by two-carbon homologation
Lower rim-phosphonylated rexorcinol calix[4]arenes by condensation reactions
α-Phosphovinyl radicals via a radical trapping sequence
Inhibitors of reverse transcriptase via 1,3-dipolar cycloadditions

Reactant for Friedel-Crafts reactions

reaction suitability

reaction type: C-C Bond Formation

Diethyl 2,2-diethoxyethylphosphonate synthesis

Synthesis of Diethyl 2,2-diethoxyethylphosphonate from Bromoacetaldehyde diethyl acetal and Triethyl phosphite

Diethyl 2,2-diethoxyethylphosphonate Preparation Products And Raw materials

Raw materials

Preparation Products

Tetraethyl ethylenediphosphonate

Diethyl 2,2-diethoxyethylphosphonate Suppliers

Global Suppliers ( 139)

Supplier	Tel	Email	Country	ProdList	Advantage
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
Beijing Donghualituo Techonlogy Development Co.,Ltd.	010-88425576	sales@dhltchem.com	China	793	59
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15813	69
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32273	50
Hunan Hui Bai Shi Biotechnology Co., Ltd.	0731-85526065 13308475853	ivy@hnhbsj.com	China	7236	62

Supplier	Advantage
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
Beijing Donghualituo Techonlogy Development Co.,Ltd.	59
3B Pharmachem (Wuhan) International Co.,Ltd.	69
Alfa Aesar	84
TCI (Shanghai) Development Co., Ltd.	81
Energy Chemical	61
Shanghai Hanhong Scientific Co.,Ltd.	64
Chemsky（shanghai）International Co.,Ltd.	50
Hunan Hui Bai Shi Biotechnology Co., Ltd.	62

Diethyl 2,2-diethoxyethylphosphonate Spectrum

DIETHYL 2,2-DIETHOXYETHYLPHOSPHONATE(7598-61-0)¹HNMR DIETHYL 2,2-DIETHOXYETHYLPHOSPHONATE(7598-61-0)FT-IR DIETHYL 2,2-DIETHOXYETHYLPHOSPHONATE(7598-61-0)Raman

7598-61-0 (Diethyl 2,2-diethoxyethylphosphonate) Related Search:

Dimethyl ethylphosphonite Diethyl ethylphosphonate Ethylphosphonic acid Methylphosphonic acid Diethyl methylphosphonate

Dimethyl methylphosphonate Dimethyl 2-hydroxyethylphosphonate Methyldiethoxyphosphine Ethyl methylphosphonic acid Dimethyl ethylphosphonate

Diethyl 2,2-diethoxyethylphosphonate Diethyl phosphate Diethyl 2,2-dimethoxyethylphosphonate 2-Hydroxyethyl phosphonic acid Ethyl methylphosphinate

Ethyl hydrogen ethylphosphonate Diethyl ethylphosphonite Methyl methylphosphonic acid

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Phosphonic acid, (2,2-diethoxyethyl)-, diethyl ester DIETHYL PHOSPHONOACETALDEHYDE DIETHYL ACETAL DIETHYL PHOSPHONACETALDEHYDE DIETHYL ACETAL DIETHYL 2,2-DIETHOXETHYLPHOSPHONATE DIETHYL 2,2-DIETHOXY-ETHANEPHOSPHONATE AURORA KA-1450 Diethyl phosphonoacetaldehyde diethyl acetal, 90%, tech. Diethyl phosphonoacetaldehyde diethyl acetal, tech. DIETHYL-2,2-DIETHOXYETHYLPHOSPONATE Diethyl(2,2-diethoxyethyl)phosphonate, 98 % 2,2-DIETHOXYETHYLPHOSPHONIC ACID DIETHYL ESTER LABOTEST-BB LT01148150 2,2-Diethoxyethylphosphonic acid diethyl ester~Diethyl phosphonoacetaldehyde diethyl acetal Phosphonic acid, P-(2,2-diethoxyethyl)-, diethyl ester Diethyl 2,2-diethoxyethyl Diethyl phosphonoacetaldehyde diethyl acetal, tech., 90% 5GR NSC 407851 NSC 77101 P-(2,2-Diethoxyethyl)phosphonic Acid Diethyl Ester Diethyl2,2-Diethoxyethylphosphonate> 2-diethoxyphosphoryl-1,1-diethoxyethane Diethyl P-(2,2-diethoxyethyl)phosphonate Diethyl 2,2-diethoxyethylphosphonate 7598-61-0 C10H23O5P CH3CH2O2CHCH2POOCH2CH32 C-C Bond Formation Horner-Wadsworth-Emmons Reagents Olefination Synthetic Reagents Horner-Emmons Reaction Wittig & Horner-Emmons Reaction Wittig Reagents Horner-Emmons Reaction Synthetic Organic Chemistry Wittig & Horner-Emmons Reaction