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DIETHYL 2,2-DIETHOXYETHYLPHOSPHONATE

CAS No.
7598-61-0
Chemical Name:
DIETHYL 2,2-DIETHOXYETHYLPHOSPHONATE
Synonyms
NSC 77101;NSC 407851;AURORA KA-1450;LABOTEST-BB LT01148150;Diethyl 2,2-diethoxyethyl;DIETHYL 2,2-DIETHOXETHYLPHOSPHONATE;DIETHYL-2,2-DIETHOXYETHYLPHOSPONATE;DIETHYL 2,2-DIETHOXYETHYLPHOSPHONATE;DIETHYL 2,2-DIETHOXY-ETHANEPHOSPHONATE;Diethyl2,2-Diethoxyethylphosphonate>
CBNumber:
CB6669966
Molecular Formula:
C10H23O5P
Molecular Weight:
254.26
MDL Number:
MFCD00009236
MOL File:
7598-61-0.mol
MSDS File:
SDS
Last updated:2026-01-13 11:24:13
Product description Number Pack Size Price
Diethyl 2,2-diethoxyethylphosphonate 95% D99250 25g $242
Diethyl 2,2-Diethoxyethylphosphonate >96.0%(GC) D2423 5g $94
Diethyl 2,2-Diethoxyethylphosphonate >96.0%(GC) D2423 25g $271
Diethyl2,2-Diethoxethylphosphonate D444210 10g $110
Diethyl 2,2-diethoxethylphosphonate FD21775 5G $140
More product size

DIETHYL 2,2-DIETHOXYETHYLPHOSPHONATE Properties

Boiling point 146-149 °C14 mm Hg(lit.)
Density 1.052 g/mL at 25 °C(lit.)
refractive index n20/D 1.430(lit.)
Flash point >230 °F
storage temp. 2-8°C
solubility Chloroform, Dichloromethane
form Oil
color Colourless
Water Solubility Soluble in chloroform and dichloromethane. Not miscible or difficult to mix in water.
Sensitive Moisture Sensitive
BRN 1785614
InChI 1S/C10H23O5P/c1-5-12-10(13-6-2)9-16(11,14-7-3)15-8-4/h10H,5-9H2,1-4H3
InChIKey LUQYELQXRPNKRY-UHFFFAOYSA-N
SMILES CCOC(CP(=O)(OCC)OCC)OCC
CAS DataBase Reference 7598-61-0(CAS DataBase Reference)
FDA UNII KS6N6SP2MG
UNSPSC Code 12352108
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39
RIDADR  UN2810
WGK Germany  3
21
HazardClass  6.1
HS Code  29319090
Storage Class 10 - Combustible liquids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Limited Quantities 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
1
2 1

DIETHYL 2,2-DIETHOXYETHYLPHOSPHONATE price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich D99250 Diethyl 2,2-diethoxyethylphosphonate 95% 7598-61-0 25g $242 2025-07-31 Buy
TCI Chemical D2423 Diethyl 2,2-Diethoxyethylphosphonate >96.0%(GC) 7598-61-0 5g $94 2025-07-31 Buy
TCI Chemical D2423 Diethyl 2,2-Diethoxyethylphosphonate >96.0%(GC) 7598-61-0 25g $271 2025-07-31 Buy
TRC D444210 Diethyl2,2-Diethoxethylphosphonate 7598-61-0 10g $110 2021-12-16 Buy
Biosynth Carbosynth FD21775 Diethyl 2,2-diethoxethylphosphonate 7598-61-0 5G $140 2021-12-16 Buy
Product number Packaging Price Buy
D99250 25g $242 Buy
D2423 5g $94 Buy
D2423 25g $271 Buy
D444210 10g $110 Buy
FD21775 5G $140 Buy

DIETHYL 2,2-DIETHOXYETHYLPHOSPHONATE Chemical Properties,Uses,Production

Chemical Properties

Colourless Oil

Uses

Diethyl 2,2-diethoxyethylphosphonate can be used as a useful wittig reagent.

Uses

Diethyl 2,2-diethoxyethylphosphonate is used reactant for synthesis of α,β-alkenal derivatives by two-carbon homologation, lower rim-phosphonylated rexorcinol calix[4]arenes by condensation reactions, α-Phosphovinyl radicals via a radical trapping sequence, inhibitors of reverse transcriptase via 1,3-dipolar cycloadditions and for Friedel-Crafts reactions.

Uses

Reactant for synthesis of:

  • α,β-Alkenal derivatives by two-carbon homologation
  • Lower rim-phosphonylated rexorcinol calix[4]arenes by condensation reactions
  • α-Phosphovinyl radicals via a radical trapping sequence
  • Inhibitors of reverse transcriptase via 1,3-dipolar cycloadditions

Reactant for Friedel-Crafts reactions

reaction suitability

reaction type: C-C Bond Formation

2032-35-1
122-52-1
7598-61-0
Synthesis of DIETHYL 2,2-DIETHOXYETHYLPHOSPHONATE from Bromoacetaldehyde diethyl acetal and Triethyl phosphite

DIETHYL 2,2-DIETHOXYETHYLPHOSPHONATE Preparation Products And Raw materials

Raw materials

Preparation Products

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Phosphonic acid, (2,2-diethoxyethyl)-, diethyl ester DIETHYL PHOSPHONOACETALDEHYDE DIETHYL ACETAL DIETHYL PHOSPHONACETALDEHYDE DIETHYL ACETAL DIETHYL 2,2-DIETHOXETHYLPHOSPHONATE DIETHYL 2,2-DIETHOXY-ETHANEPHOSPHONATE DIETHYL 2,2-DIETHOXYETHYLPHOSPHONATE AURORA KA-1450 Diethyl phosphonoacetaldehyde diethyl acetal, 90%, tech. Diethyl phosphonoacetaldehyde diethyl acetal, tech. DIETHYL-2,2-DIETHOXYETHYLPHOSPONATE Diethyl(2,2-diethoxyethyl)phosphonate, 98 % 2,2-DIETHOXYETHYLPHOSPHONIC ACID DIETHYL ESTER LABOTEST-BB LT01148150 2,2-Diethoxyethylphosphonic acid diethyl ester~Diethyl phosphonoacetaldehyde diethyl acetal Phosphonic acid, P-(2,2-diethoxyethyl)-, diethyl ester Diethyl 2,2-diethoxyethyl Diethyl phosphonoacetaldehyde diethyl acetal, tech., 90% 5GR NSC 407851 NSC 77101 P-(2,2-Diethoxyethyl)phosphonic Acid Diethyl Ester Diethyl2,2-Diethoxyethylphosphonate> 2-diethoxyphosphoryl-1,1-diethoxyethane Diethyl P-(2,2-diethoxyethyl)phosphonate 7598-61-0 C10H23O5P CH3CH2O2CHCH2POOCH2CH32 C-C Bond Formation Horner-Wadsworth-Emmons Reagents Olefination Synthetic Reagents Horner-Emmons Reaction Wittig & Horner-Emmons Reaction Wittig Reagents Horner-Emmons Reaction Synthetic Organic Chemistry Wittig & Horner-Emmons Reaction