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2-Methylthio-4-pyrimidinol

2-Methylthio-4-pyrimidinol Structure
2-Methylthio-4-pyrimidinol structure
CAS No.
5751-20-2
Chemical Name:
2-Methylthio-4-pyrimidinol
Synonyms
2-(METHYLTHIO)PYRIMIDIN-4(3H)-ONE;2-(Methylthio)pyriMidin-4(1H)-one;NSC 125339;NSC 165518;AURORA 15138;2-Methyl Uracil;2-Methylthiouracil;2-Methylthio-4-pyrim;S-Methyl-2-thiouracil;2-Methylo-4-pyriMidinol
CBNumber:
CB6690290
Molecular Formula:
C5H6N2OS
Molecular Weight:
142.18
MDL Number:
MFCD00955672
MOL File:
5751-20-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 02:53:17
Product description Number Pack Size Price
2-METHYLTHIO-4-PYRIMIDINOL AldrichCPR S440043 1 unit $121
2-METHYLTHIO-4-PYRIMIDINOL Aldrich S440043 250mg $110
2-METHYLSULFANYL-PYRIMIDIN-4-OL AldrichCPR S217336 25MG $28.6
2-Methylthio-4-pyrimidinol >98.0%(HPLC)(T) M2355 1g $17
2-Methylthio-4-pyrimidinol >98.0%(HPLC)(T) M2355 5g $46
More product size
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2-Methylthio-4-pyrimidinol Properties

Melting point 200.0 to 204.0 °C
Density 1.35±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 7.80±0.40(Predicted)
color White to Off-White
InChI InChI=1S/C5H6N2OS/c1-9-5-6-3-2-4(8)7-5/h2-3H,1H3,(H,6,7,8)
InChIKey UYHSQVMHSFXUOA-UHFFFAOYSA-N
SMILES C1(SC)=NC=CC(=O)N1
CAS DataBase Reference 5751-20-2(CAS DataBase Reference)
NIST Chemistry Reference 4(1H)-Pyrimidinone, 2-(methylthio)-(5751-20-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)Corrosion (GHS05)
GHS07,GHS05
Signal word  Danger
Hazard statements  H335-H315-H318-H302
Precautionary statements  P280-P305+P351+P338-P310-P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501
Risk Statements  22-37/38-41
Safety Statements  26-39
HS Code  29335990

2-Methylthio-4-pyrimidinol price More Price(73)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S440043 2-METHYLTHIO-4-PYRIMIDINOL AldrichCPR 5751-20-2 1 unit $121 2026-04-30 Buy
Sigma-Aldrich S440043 2-METHYLTHIO-4-PYRIMIDINOL Aldrich 5751-20-2 250mg $110 2024-03-01 Buy
Sigma-Aldrich S217336 2-METHYLSULFANYL-PYRIMIDIN-4-OL AldrichCPR 5751-20-2 25MG $28.6 2023-06-20 Buy
TCI Chemical M2355 2-Methylthio-4-pyrimidinol >98.0%(HPLC)(T) 5751-20-2 1g $17 2026-04-30 Buy
TCI Chemical M2355 2-Methylthio-4-pyrimidinol >98.0%(HPLC)(T) 5751-20-2 5g $46 2026-04-30 Buy
Product number Packaging Price Buy
S440043 1 unit $121 Buy
S440043 250mg $110 Buy
S217336 25MG $28.6 Buy
M2355 1g $17 Buy
M2355 5g $46 Buy

2-Methylthio-4-pyrimidinol Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

A competitive inhibitor of Nitric Oxide Synthase (NOS).

Definition

ChEBI: 2-methylthiouracil is an aryl sulfide.

Synthesis

Sequentially, 800g of 2-thiouracil and 6L of water were added to a 10L reaction flask and stirred. Ice bath cooling, add sodium hydroxide 560g to the reaction bottle in batches, maintain the temperature below 40. After the addition, the ice bath was cooled down to below 20 , and 944g of dimethyl sulfate was slowly added dropwise, and the temperature was controlled between 15-25 during the dropwise process, and after the dropwise process, the reaction was kept warm for 4 h. The raw materials were basically reacted by HPLC. The reaction solution was adjusted to pH 1-2 with 6 mol/L dilute hydrochloric acid, and a white solid was precipitated. Decrease to about 20 , stirring 0.5h, filtration, filter cake with a large number of water to remove salt, pump dry, 50 air drying. Obtained 805g of white solid powder, more than 98% of the liquid phase, yield 90.7%.

2-Methylthio-4-pyrimidinol synthesis

141-90-2
616-38-6
5751-20-2
Synthesis of 2-Methylthio-4-pyrimidinol from 2-Thiouracil and Dimethyl carbonate

2-Methylthio-4-pyrimidinol Preparation Products And Raw materials

Raw materials

2-Thiouracil Iodomethane 4(1H)-Pyrimidinone, 1-methyl-2-(methylthio)- 4(1H)-Pyrimidinone, 2,3-dihydro-1,3-dimethyl-2-thioxo- Isopropyl forMylacetate
(E)-methyl (dimethylamino)methylenecarbamimidothioate hydroiodide 2-Methylthio-4-MethoxypyriMidine TERT-BUTYL 3-OXOPROPIONATE 2-(Methylthio)-3-methylpyrimidine-4(3H)-one Boron trifluoride methyl sulfide complex
3-OXO-PROPIONIC ACID ETHYL ESTER methyl 3-oxopropanoate

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Preparation Products

N-(4-AMINOPYRIMIDIN-2-YL)-N-METHYLAMINE 5-Bromo-2-methoxypyrimidine 5-BROMO-2-(METHYLTHIO)PYRIMIDINE 4-Chloro-2-methylthiopyrimidine Pyrimidine, 4,5-dichloro-2-(methylthio)-
5-bromo-2-methylsulfanyl-3H-pyrimidin-4-one 2-METHYLTHIO-4-BROMOPYRIMIDINE

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2-Methylthio-4-pyrimidinol Suppliers

Global( 335)Suppliers
Supplier Tel Email Country ProdList Advantage
Chongqing Soarwin Technology Co., Ltd 		+86-15790943001 crystal@sorawin.cn China 421 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29640 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21585 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29812 58
Jinan Carbotang Biotech Co.,Ltd. 		+8615866703830 figo.gao@foxmail.com China 8497 58
Accela ChemBio Inc. 		+1-858-6993322 info@accelachem.com United States 21193 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
Shanghai Yingrui Biopharma Co.,Ltd 		21-33585366 export01@shyrchem.com CHINA 1319 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49979 58
Supplier Advantage
Chongqing Soarwin Technology Co., Ltd 		58
Capot Chemical Co.,Ltd. 		60
Henan Tianfu Chemical Co.,Ltd. 		55
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Jinan Carbotang Biotech Co.,Ltd. 		58
Accela ChemBio Inc. 		58
Alchem Pharmtech,Inc. 		58
Shanghai Yingrui Biopharma Co.,Ltd 		58
CONIER CHEM AND PHARMA LIMITED 		58

View Lastest Price from 2-Methylthio-4-pyrimidinol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Methylthio-4-pyrimidinol pictures 2026-06-30 2-Methylthio-4-pyrimidinol
5751-20-2
 1kg 99% 10000KGS Shaanxi Dideu New Materials Co. Ltd
2-Methylthio-4-pyrimidinol pictures 2025-11-18 2-Methylthio-4-pyrimidinol
5751-20-2
 $1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited
2-Methylthio-4-pyrimidinol pictures 2025-08-20 2-Methylthio-4-pyrimidinol
5751-20-2
 1kg 99.99% 20 tons Chongqing Soarwin Technology Co., Ltd

2-Methylthio-4-pyrimidinol Spectrum

2-Methylthio-4-pyrimidinol(5751-20-2)1HNMR

5751-20-2(2-Methylthio-4-pyrimidinol )Related Search:

ISOMETHIOZIN Zinc pyrithione 4-Pyrimidinol Diltiazem hydrochloride Mizolastine Impurity 8
Mizolastine Impurity 3 Acetate Mizolastine Impurity 9 1-[1-(4-Fluorobenzyl)-1H-BenziMidazole-2yl]-N-Methyl-4-piperidineaMine Mizolastine Impurity 5 Mizolastine Impurity N
Mizolastine Impurity 7 1-(4-Fluorobenzyl)-2-chlorobenzimidazole Mizolastine Impurity 11 pyrimidone ETHYL 5-OXO-2,3-DIHYDRO-5H-PYRIMIDO[2,1-B][1,3]THIAZOLE-6-CARBOXYLATE
Methylthiouracil NICKEL AND VANADIUM IN RESIDUAL FUEL OIL DIACYLGLYCEROL KINASE INHIBITOR I

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2-(Methylsulfanyl)pyrimidin-4-ol ,98% 2-METHYLSULFANYL-4-OXOPYRIMIDINE 2-methylthiopyrimidin-4-one 2-(Methylthio)pyrimidine-4(1H)-one 2-Methylthio-4(3H)-pyrimidone (2R,3R,4S,5R)-2-amino-3,4,5,6-tetrahydroxyhexanal (2R,3R,4S,5R)-2-amino-3,4,5,6-tetrahydroxy-hexanal (2R,3R,4S,5R)-2-azanyl-3,4,5,6-tetrahydroxy-hexanal 2-METHYLTHIO-4-PYRIMIDONE 98.5+% 4(3H)-Pyrimidinone, 2-(methylthio)- 2-Methylo-4-pyrimidinol ,98% 2-Methylthio-4-pyrim 2-(Methylthio)pyrimidin-4... 2-Methylsulfanyl-1H-pyrimidin-4-one 2-Methyl Uracil 2-Methylthio-4-pyrimidinol 2-METHYLTHIO-4-PYRIMIDONE 98.5+% 2-Methyl-1-sulfanylpyriMidin-4-ol 2-(Methylthio)pyriMidin-4(1H)-one 2-(Methylthio)-4(3H)-PyriMidinone 2-(Methylthio)pyriMidine-4(3H)-one 2-Methylthio-3H-pyriMidin-4-one NSC 125339 NSC 165518 2-Methylo-4-pyriMidinol 2-Methylthio-4(3H)-pyriMidinone, cont. ca 12% 6-hydroxy-2-Methylthio-4(3H)-pyriMidinone 2-Methylthio-4-pyrimidinol 2-(Methylthio)-4(1H)-pyrimidinone 2-(methylsulfanyl)-3,4-dihydropyrimidin-4-one 2-Methylsulfanylpyrimidin-4(3H)-one 2-(Methylsulfanyl)-4-pyrimidinol 2-Methylthiouracil 4-Hydroxy-2-methylthiopyrimidine 4-Pyrimidinol, 2-(methylthio)- AURORA 15138 2-Methylthio-4-Pyrimidinone 2-(Methylthio)-4(1H)- pyrimidinone(MTP) 4(1H)-Pyrimidinone, 2-(methylthio)- (8CI,9CI) 2-(METHYLSULFANYL)PYRIMIDIN-4-OL 2-METHYLTHIO-4-HYDROXY PYRIMIDINE 2-(METHYLTHIO)-4(1H)-PYRIMIDINONE 2-(Methylthio)-1H-pyrimidin-4-one 2-METHYLTHIOPYRIMIDIN-4-OL 2-Methylthio-4-pyrimidinol 2-METHYLTHIO-4-PYRIMIDONE 2-METHYLSULFANYL-3H-PYRIMIDIN-4-ONE 2-Methylthio-4-pyrimidinol> Mizolastine Impurity 16 2-Methylthio-4-pyrimidino S-Methyl-2-thiouracil 2-Methylthio-4-pyrimidinol ISO 9001：2015 REACH 2-(methylthioyl)pyrimidine-4(3H)-one 2-(METHYLTHIO)PYRIMIDIN-4(3H)-ONE 5751-20-2 Heterocycles Sulfur & Selenium Compounds (intermediate of mizolastine) Aromatics PYRIMIDINE