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2-Methylthio-4-pyrimidinol

2-Methylthio-4-pyrimidinol Structure
2-Methylthio-4-pyrimidinol structure
CAS No.
5751-20-2
Chemical Name:
2-Methylthio-4-pyrimidinol
Synonyms
2-(METHYLTHIO)PYRIMIDIN-4(3H)-ONE;2-(Methylthio)pyriMidin-4(1H)-one;NSC 125339;NSC 165518;AURORA 15138;2-Methyl Uracil;2-Methylthiouracil;2-Methylthio-4-pyrim;S-Methyl-2-thiouracil;2-Methylo-4-pyriMidinol
CBNumber:
CB6690290
Molecular Formula:
C5H6N2OS
Molecular Weight:
142.18
MDL Number:
MFCD00955672
MOL File:
5751-20-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 02:53:17
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2-Methylthio-4-pyrimidinol Properties

Melting point 200.0 to 204.0 °C
Density 1.35±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 7.80±0.40(Predicted)
color White to Off-White
InChI InChI=1S/C5H6N2OS/c1-9-5-6-3-2-4(8)7-5/h2-3H,1H3,(H,6,7,8)
InChIKey UYHSQVMHSFXUOA-UHFFFAOYSA-N
SMILES C1(SC)=NC=CC(=O)N1
CAS DataBase Reference 5751-20-2(CAS DataBase Reference)
NIST Chemistry Reference 4(1H)-Pyrimidinone, 2-(methylthio)-(5751-20-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)Corrosion (GHS05)
GHS07,GHS05
Signal word  Danger
Hazard statements  H335-H315-H318-H302
Precautionary statements  P280-P305+P351+P338-P310-P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501
Risk Statements  22-37/38-41
Safety Statements  26-39
HS Code  29335990

2-Methylthio-4-pyrimidinol price More Price(63)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S440043 2-METHYLTHIO-4-PYRIMIDINOL AldrichCPR 5751-20-2 1 unit $121 2026-04-30 Buy
Sigma-Aldrich S440043 2-METHYLTHIO-4-PYRIMIDINOL Aldrich 5751-20-2 250mg $110 2024-03-01 Buy
Sigma-Aldrich S217336 2-METHYLSULFANYL-PYRIMIDIN-4-OL AldrichCPR 5751-20-2 25MG $28.6 2023-06-20 Buy
TCI Chemical M2355 2-Methylthio-4-pyrimidinol >98.0%(HPLC)(T) 5751-20-2 1g $17 2026-04-30 Buy
TCI Chemical M2355 2-Methylthio-4-pyrimidinol >98.0%(HPLC)(T) 5751-20-2 5g $46 2026-04-30 Buy
Product number Packaging Price Buy
S440043 1 unit $121 Buy
S440043 250mg $110 Buy
S217336 25MG $28.6 Buy
M2355 1g $17 Buy
M2355 5g $46 Buy

2-Methylthio-4-pyrimidinol Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

A competitive inhibitor of Nitric Oxide Synthase (NOS).

Definition

ChEBI: 2-methylthiouracil is an aryl sulfide.

Synthesis

Sequentially, 800g of 2-thiouracil and 6L of water were added to a 10L reaction flask and stirred. Ice bath cooling, add sodium hydroxide 560g to the reaction bottle in batches, maintain the temperature below 40. After the addition, the ice bath was cooled down to below 20 , and 944g of dimethyl sulfate was slowly added dropwise, and the temperature was controlled between 15-25 during the dropwise process, and after the dropwise process, the reaction was kept warm for 4 h. The raw materials were basically reacted by HPLC. The reaction solution was adjusted to pH 1-2 with 6 mol/L dilute hydrochloric acid, and a white solid was precipitated. Decrease to about 20 , stirring 0.5h, filtration, filter cake with a large number of water to remove salt, pump dry, 50 air drying. Obtained 805g of white solid powder, more than 98% of the liquid phase, yield 90.7%.

2-Methylthio-4-pyrimidinol synthesis

141-90-2
616-38-6
5751-20-2
Synthesis of 2-Methylthio-4-pyrimidinol from 2-Thiouracil and Dimethyl carbonate

2-Methylthio-4-pyrimidinol Preparation Products And Raw materials

Raw materials

2-Thiouracil Iodomethane 4(1H)-Pyrimidinone, 1-methyl-2-(methylthio)- 4(1H)-Pyrimidinone, 2,3-dihydro-1,3-dimethyl-2-thioxo- Isopropyl forMylacetate
(E)-methyl (dimethylamino)methylenecarbamimidothioate hydroiodide 2-Methylthio-4-MethoxypyriMidine tert-Butyl 3-oxopropionate 2-(Methylthio)-3-methylpyrimidine-4(3H)-one Boron trifluoride methyl sulfide complex
3-Oxo-propionic acid ethyl ester methyl 3-oxopropanoate

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Preparation Products

N-(4-Aminopyrimidin-2-yl)-N-methylamine 5-Bromo-2-methoxypyrimidine 5-Bromo-2-(methylthio)pyrimidine 4-Chloro-2-methylthiopyrimidine Pyrimidine, 4,5-dichloro-2-(methylthio)-
5-bromo-2-methylsulfanyl-3H-pyrimidin-4-one 2-Methylthio-4-bromopyrimidine

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2-Methylthio-4-pyrimidinol Suppliers

Global( 336)Suppliers
Supplier Tel Email Country ProdList Advantage
Xi'an Yutebang New Material Technology Co., Ltd. 029-84536388 19991842844 ella@yutbon.com China 155 58
Nanjing Yiyuan 18915107665 18061915908 wwwang2011@163.com China 30 58
Shandong Chenyi Environmental Protection Technology Co., Ltd 0531-83179999 13395316108 cyhbkjyxgs@163.com China 196 58
Suzhou Guide Fine Material Co.Ltd. 0512-66627360 13914021065 706938434@qq.com China 202 60
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TAIYUAN RHF CO.,LTD. +86 351 7031519 sales@RHFChem.com China 2334 56
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
Supplier Advantage
Xi'an Yutebang New Material Technology Co., Ltd. 58
Nanjing Yiyuan 58
Shandong Chenyi Environmental Protection Technology Co., Ltd 58
Suzhou Guide Fine Material Co.Ltd. 60
J & K SCIENTIFIC LTD. 76
Alfa Aesar 84
TAIYUAN RHF CO.,LTD. 56
TCI (Shanghai) Development Co., Ltd. 81
Energy Chemical 61
Beijing Ouhe Technology Co., Ltd 60

View Lastest Price from 2-Methylthio-4-pyrimidinol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Methylthio-4-pyrimidinol pictures 2026-08-20 2-Methylthio-4-pyrimidinol
5751-20-2
 $1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited
2-Methylthio-4-pyrimidinol pictures 2026-06-30 2-Methylthio-4-pyrimidinol
5751-20-2
 1kg 99% 10000KGS Shaanxi Dideu New Materials Co. Ltd
2-Methylthio-4-pyrimidinol pictures 2025-08-20 2-Methylthio-4-pyrimidinol
5751-20-2
 1kg 99.99% 20 tons Chongqing Soarwin Technology Co., Ltd

2-Methylthio-4-pyrimidinol Spectrum

2-Methylthio-4-pyrimidinol(5751-20-2)1HNMR

5751-20-2(2-Methylthio-4-pyrimidinol )Related Search:

Zinc pyrithione 4-Pyrimidinol Diltiazem hydrochloride Mizolastine Impurity 8 Mizolastine Impurity 3 Acetate
Mizolastine Impurity 9 1-[1-(4-Fluorobenzyl)-1H-BenziMidazole-2yl]-N-Methyl-4-piperidineaMine Mizolastine Impurity 5 Mizolastine Impurity N Mizolastine Impurity 7
1-(4-Fluorobenzyl)-2-chlorobenzimidazole Mizolastine Impurity 11 Isomethiozin pyrimidone ETHYL 5-OXO-2,3-DIHYDRO-5H-PYRIMIDO[2,1-B][1,3]THIAZOLE-6-CARBOXYLATE
Methylthiouracil NICKEL AND VANADIUM IN RESIDUAL FUEL OIL DIACYLGLYCEROL KINASE INHIBITOR I

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2-(Methylsulfanyl)pyrimidin-4-ol ,98% 2-METHYLSULFANYL-4-OXOPYRIMIDINE 2-methylthiopyrimidin-4-one 2-(Methylthio)pyrimidine-4(1H)-one 2-Methylthio-4(3H)-pyrimidone (2R,3R,4S,5R)-2-amino-3,4,5,6-tetrahydroxyhexanal (2R,3R,4S,5R)-2-amino-3,4,5,6-tetrahydroxy-hexanal (2R,3R,4S,5R)-2-azanyl-3,4,5,6-tetrahydroxy-hexanal 2-METHYLTHIO-4-PYRIMIDONE 98.5+% 4(3H)-Pyrimidinone, 2-(methylthio)- 2-Methylo-4-pyrimidinol ,98% 2-Methylthio-4-pyrim 2-(Methylthio)pyrimidin-4... 2-Methylsulfanyl-1H-pyrimidin-4-one 2-Methyl Uracil 2-Methylthio-4-pyrimidinol 2-METHYLTHIO-4-PYRIMIDONE 98.5+% 2-Methyl-1-sulfanylpyriMidin-4-ol 2-(Methylthio)pyriMidin-4(1H)-one 2-(Methylthio)-4(3H)-PyriMidinone 2-(Methylthio)pyriMidine-4(3H)-one 2-Methylthio-3H-pyriMidin-4-one NSC 125339 NSC 165518 2-Methylo-4-pyriMidinol 2-Methylthio-4(3H)-pyriMidinone, cont. ca 12% 6-hydroxy-2-Methylthio-4(3H)-pyriMidinone 2-Methylthio-4-pyrimidinol 2-(Methylthio)-4(1H)-pyrimidinone 2-(methylsulfanyl)-3,4-dihydropyrimidin-4-one 2-Methylsulfanylpyrimidin-4(3H)-one 2-(Methylsulfanyl)-4-pyrimidinol 2-Methylthiouracil 4-Hydroxy-2-methylthiopyrimidine 4-Pyrimidinol, 2-(methylthio)- AURORA 15138 2-Methylthio-4-Pyrimidinone 2-(Methylthio)-4(1H)- pyrimidinone(MTP) 4(1H)-Pyrimidinone, 2-(methylthio)- (8CI,9CI) 2-(METHYLSULFANYL)PYRIMIDIN-4-OL 2-METHYLTHIO-4-HYDROXY PYRIMIDINE 2-(METHYLTHIO)-4(1H)-PYRIMIDINONE 2-(Methylthio)-1H-pyrimidin-4-one 2-METHYLTHIOPYRIMIDIN-4-OL 2-Methylthio-4-pyrimidinol 2-METHYLTHIO-4-PYRIMIDONE 2-METHYLSULFANYL-3H-PYRIMIDIN-4-ONE 2-Methylthio-4-pyrimidinol> Mizolastine Impurity 16 2-Methylthio-4-pyrimidino S-Methyl-2-thiouracil 2-Methylthio-4-pyrimidinol ISO 9001：2015 REACH 2-(methylthioyl)pyrimidine-4(3H)-one 2-(METHYLTHIO)PYRIMIDIN-4(3H)-ONE 5751-20-2 Heterocycles Sulfur & Selenium Compounds (intermediate of mizolastine) Aromatics PYRIMIDINE