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ChemicalBook >> CAS DataBase List >>1,1,1-Trifluoro-2,4-pentanedione

1,1,1-Trifluoro-2,4-pentanedione

1,1,1-Trifluoro-2,4-pentanedione Structure
1,1,1-Trifluoro-2,4-pentanedione structure
CAS No.
367-57-7
Chemical Name:
1,1,1-Trifluoro-2,4-pentanedione
Synonyms
1,1,1-Trifluoropentane-2,4-dione;TRIFLUOROACETYLACETONE;tfacac;Tfpd-H;(Trifluor;AKOS MSC-0319;CF3COH=CHCOCH3;1,1,1-Trifluoro-2,4-;Trifluoro-2,4-pentane;uoro-2,4-pentanedione
CBNumber:
CB6699233
Molecular Formula:
C5H5F3O2
Molecular Weight:
154.09
MDL Number:
MFCD00000427
MOL File:
367-57-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 03:02:13
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1,1,1-Trifluoro-2,4-pentanedione Properties

Boiling point 105-107 °C (lit.)
Density 1.27 g/mL at 25 °C (lit.)
refractive index n20/D 1.388(lit.)
Flash point 79 °F
storage temp. 2-8°C
form Liquid
pka 6.69±0.10(Predicted)
Specific Gravity 1.270
color deep brownish-yellow
Water Solubility slightly soluble
BRN 1705177
InChI InChI=1S/C5H5F3O2/c1-3(9)2-4(10)5(6,7)8/h2H2,1H3
InChIKey SHXHPUAKLCCLDV-UHFFFAOYSA-N
SMILES C(F)(F)(F)C(=O)CC(=O)C
CAS DataBase Reference 367-57-7(CAS DataBase Reference)
FDA UNII 9N20A8G8SW
NIST Chemistry Reference 2,4-Pentanedione, 1,1,1-trifluoro-(367-57-7)
EPA Substance Registry System 2,4-Pentanedione, 1,1,1-trifluoro- (367-57-7)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Exclamation Mark (GHS07)
GHS02,GHS07
Signal word  Warning
Hazard statements  H226-H302+H312+H332
Precautionary statements  P210-P280-P301+P312+P330-P302+P352+P312-P304+P340+P312
PPE Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xn,F,Xi
Risk Statements  10-20/21/22-36/37/38
Safety Statements  36/37-36/37/39-26-16
RIDADR  UN 1224 3/PG 3
WGK Germany  3
Hazard Note  Flammable/Irritant
TSCA  TSCA listed
HazardClass  3
PackingGroup  III
HS Code  29147090
Storage Class 3 - Flammable liquids
Hazard Classifications Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Flam. Liq. 3
Limited Quantities 5.0 L (1.3 gallons) (liquid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
2
2 0

1,1,1-Trifluoro-2,4-pentanedione price More Price(48)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 235970 1,1,1-Trifluoro-2,4-pentanedione 98% 367-57-7 10g $93.6 2026-04-30 Buy
Sigma-Aldrich 235970 1,1,1-Trifluoro-2,4-pentanedione 98% 367-57-7 25g $112 2026-04-30 Buy
TCI Chemical T0434 Trifluoroacetylacetone >98.0%(GC) 367-57-7 25g $70 2026-04-30 Buy
TCI Chemical T0434 Trifluoroacetylacetone >98.0%(GC) 367-57-7 100g $202 2026-04-30 Buy
Strem Chemicals 09-7210 1,1,1-Trifluoroacetylacetone, min. 98% min.98% 367-57-7 10g $65 2026-04-30 Buy
Product number Packaging Price Buy
235970 10g $93.6 Buy
235970 25g $112 Buy
T0434 25g $70 Buy
T0434 100g $202 Buy
09-7210 10g $65 Buy

1,1,1-Trifluoro-2,4-pentanedione Chemical Properties,Uses,Production

Synthesis

method for synthesizing 1,1,1-trifluoro-2,4-pentanedione is disclosed, which involves the Claisen condensation reaction using ethyl trifluoroacetate and acetone as raw materials. Experiments show that the optimal conditions for synthesizing 1,1,1-trifluoro-2,4-pentanedione are: using an ethanolic solution of sodium ethoxide as a catalyst, anhydrous diethyl ether as a solvent, and reacting at 30°C for 2 h, achieving a yield of 33%. The structure of 1,1,1-trifluoro-2,4-pentanedione was confirmed by elemental analysis, infrared spectroscopy, and proton nuclear magnetic resonance spectroscopy. The synthetic reaction formula is shown in the figure below:

Synthesis of 367-57-7

Figure 1,1,1-Trifluoro-2,4-pentanedione synthetic reaction formula

Chemical Properties

Clear light yellow to orange liquid

Uses

1,1,1-Trifluoro-2,4-pentanedione has been used as reagent in the preparation of 2-alkylcarbonyl and 2-benzoyl-3-trifluoromethylquinoxaline 1,4-di-N-oxide derivatives.

General Description

1,1,1-Trifluoro-2,4-pentanedione is known as trifluoro-acetylacetone (TFAA). Molecular structure of 1,1,1-trifluoro-pentane-2,4-dione has been investigated by Density Functional Theory (DFT) calculations.

1,1,1-Trifluoro-2,4-pentanedione Preparation Products And Raw materials

Raw materials

Preparation Products

5-Trifluoromethyl-1H-pyrazole-3-carboxylic acid 3-Methyl-5-(trifluoromethyl)pyrazole 4-Methyl-6-trifluoromethyl-pyrimidine-2-thiol 6-Methyl-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile 6-Methyl-4-(trifluoromethyl)-2(1H)-pyridone
2-Chloro-6-methyl-4-(trifluoromethyl)pyridine Thiazole, 4-(4-methoxyphenyl)-2-[3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]- 3-Chloro-1,1,1-trifluoro-pentane-2,4-dione 2-Mercapto-6-methyl-4-(trifluoromethyl)nicotinonitrile

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1,1,1-Trifluoro-2,4-pentanedione Suppliers

Global( 328)Suppliers
Supplier Tel Email Country ProdList Advantage
jinanzhonglanhuagongyouxiangongsi 15169176553; 15169176553 644658103@qq.com China 32 58
West fluorine technology co., ltd 0531-85906692 15588812394 325912682@qq.com China 370 58
Hangzhou Cedareal Technology Co., Ltd. 13858087543 368073698@qq.com China 46 58
Jinan Wanxingda New Material Technology Co., Ltd. 0531-88064106 18253116016 zhangjia@wxdchem.com China 44 58
Jinan Langhua Chemical Co., Ltd 0531-85906691 18660816586 325912681@qq.com China 212 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Supplier Advantage
jinanzhonglanhuagongyouxiangongsi 58
West fluorine technology co., ltd 58
Hangzhou Cedareal Technology Co., Ltd. 58
Jinan Wanxingda New Material Technology Co., Ltd. 58
Jinan Langhua Chemical Co., Ltd 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
Energy Chemical 61

View Lastest Price from 1,1,1-Trifluoro-2,4-pentanedione manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1,1,1-Trifluoroacetylacetone pictures 2026-09-02 1,1,1-Trifluoroacetylacetone
367-57-7
 $1.00-111.00 1KG 99% Henan Fengda Chemical Co., Ltd
1, 1, 1-Trifluoro-2, 4-Pentanedione pictures 2026-05-28 1, 1, 1-Trifluoro-2, 4-Pentanedione
367-57-7
 $2.00-5.00 1KG 99% 10000kg Hebei Chuanghai Biotechnology Co,.LTD
1,1,1-Trifluoro-2,4-pentanedione pictures 2025-06-27 1,1,1-Trifluoro-2,4-pentanedione
367-57-7
 $10.00-30.00 50KG 99% 500000kg Hebei Chuanghai Biotechnology Co., Ltd

1,1,1-Trifluoro-2,4-pentanedione Spectrum

1,1,1-Trifluoro-2,4-pentanedione(367-57-7)MS1,1,1-Trifluoro-2,4-pentanedione(367-57-7)1HNMR1,1,1-Trifluoro-2,4-pentanedione(367-57-7)13CNMR1,1,1-Trifluoro-2,4-pentanedione(367-57-7)IR11,1,1-Trifluoro-2,4-pentanedione(367-57-7)Raman1,1,1-Trifluoro-2,4-pentanedione(367-57-7)ESR

367-57-7(1,1,1-Trifluoro-2,4-pentanedione)Related Search:

Cobaltic acetylacetonate Nickel(II) acetylacetonate Trifluoroacetic acid 2,3-Pentanedione Manganic acetylacetonate
Acetylacetone Trifluoromethanesulfonic acid Calcium acetylacetonate VANADIUM(III) ACETYLACETONATE (Trifluoromethoxy)benzene
Cupric acetylacetonate 3-Fluorobenzotrifluoride FLUOROLUBE GREASE, GR-362 Zinc(II) acetylacetonate λ-Cyhalothrin
Benzotrifluoride Ferric acetylacetonate Trifluoroacetic anhydride

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1,1,1-Trifluoro-2,4-pentadione 1,1,1-trifluoro-4-pentanedione 1,1,1-Trifluoroacetylacetone99% 1,1,1-TRIFLUOROACETOACETONE 1,1,1-TRIFLUORO-2,4-PENTANEDIONE TRIFLUOROACETYLACETONE 1,1,1-TRIFLUORO-2,4-PENTANEDIONE 99% 4-Pentanedione,1,1,1-trifluoro-2 CF3COH=CHCOCH3 α,α,α-Trifluoroacetylacetone, 1,1,1-Trifluoroacetylacetone 1,1,1-Trifluoroacetylacetone, min. 98% tfacac 1,1,1-Trifluoro-2,4- 1,1,1-Trifluoropentane-2,4-dione 99% 1,1,1-Trifluoropentane-2,4-dione, 97%+ (Trifluoroacetyl)acetone, 2,4-Dioxo-1,1,1-trifluoropentane 1,1,1-Trifluoro-2,4-pentanedione, 98% 10ML 1,1,1-Trifluoro-2,4-pentanedione,98% 1,1,1-Trifluoro-2,4-pentanedione, 98% 25ML Trifluoro-2,4-pentane (Trifluoroacetyl)acetone, 2,4-Dioxo-1,1,1-trifluoropentane, 1,1,1-Trifluoroacetylacetone 1,1,1-Trifluoroacetylacetone,98% α,α,α-Trifluoroacetylacetone 1,1,1-Trifluoroacetylacetone 1,1,1-Trifluoro-2,4-pentanedione 1,1,1-TRIFLUORO-2,4-PENTANEDIONE 1,1,1-TRIFLUOROACETYLACETONE AKOS MSC-0319 ALPHA,ALPHA,ALPHA-TRIFLUOROACETYLACETONE ACETYL TRIFLUOROACETONE Tfpd-H 1,1,1-Trifluoroacetylacetone,min.98% 2,4-Pentanedione, 1,1,1-trifluoro- 1,1,1-Trifluoroacetylacetone 99% (Trifluor Trifluoroacetylacetone > uoro-2,4-pentanedione 1,1,1-TRIFLUOROACETYLACETONE 1,1,1-Trifluoro-2,4-pentanedione α,α,α-Trifluoroacetylacetone 1,1,1-Trifluoropentane-2,4-dione TRIFLUOROACETYLACETONE 367-57-7 367-22-1 CF3COCH2COCH3 CH3COCH2COCF3 C5H5F3O2 KETONE Organic Building Blocks C3 to C6 Carbonyl Compounds Building Blocks Ketones Environmentally-friendly Oxidation Ligands (Environmentally-friendly Oxidation) API intermediates Environmentally-friendly Oxidation Ligands (Environmentally-friendly Oxidation) Synthetic Organic Chemistry organofluorine compounds Achiral Oxygen Building Blocks C3 to C6