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5-Phenylpenta-2,4-dienoic acid

CAS No.
1552-94-9
Chemical Name:
5-Phenylpenta-2,4-dienoic acid
Synonyms
JUAREZIC ACID;5-PHENYL-2,4-PENTADIENOIC ACID;BL 1255;Nsc 1778;Nsc 63972;Nsc 109408;AKOS B004062;Einecs 216-298-2;B-STYRYLACRYLIC ACID;BETA-STYRYLACRYLIC ACID
CBNumber:
CB6737386
Molecular Formula:
C11H10O2
Molecular Weight:
174.2
MDL Number:
MFCD00014018
MOL File:
1552-94-9.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:54:23

5-Phenylpenta-2,4-dienoic acid Properties

Melting point 165-166°C
Boiling point 356.1±21.0 °C(Predicted)
Density 1.148
storage temp. Sealed in dry,Room Temperature
solubility Soluble in DMSO
form powder
pka 4.56±0.10(Predicted)
color Pale yellow
Water Solubility Insoluble in water.
BRN 2042414
InChI InChI=1S/C11H10O2/c12-11(13)9-5-4-8-10-6-2-1-3-7-10/h1-9H,(H,12,13)
InChIKey FEIQOMCWGDNMHM-UHFFFAOYSA-N
SMILES C(O)(=O)C=CC=CC1=CC=CC=C1
CAS DataBase Reference 1552-94-9(CAS DataBase Reference)
EPA Substance Registry System 2,4-Pentadienoic acid, 5-phenyl- (1552-94-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Risk Statements  36/37/38
Safety Statements  26-36
TSCA  TSCA listed
HS Code  2916199590
NFPA 704
0
2 0

5-Phenylpenta-2,4-dienoic acid price More Price(33)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth FP70999 5-Phenylpenta-2,4-dienoic acid 1552-94-9 100g $228 2026-06-04 Buy
Biosynth FP70999 5-Phenylpenta-2,4-dienoic acid 1552-94-9 250g $520 2026-06-04 Buy
Biosynth FP70999 5-Phenylpenta-2,4-dienoic acid 1552-94-9 500g $845 2026-06-04 Buy
ChemScene CS-0030694 Cinnamylideneacetic acid ≥97% 1552-94-9 25g $136 2026-06-04 Buy
ChemScene CS-0030694 Cinnamylideneacetic acid ≥97% 1552-94-9 100g $435 2026-06-04 Buy
Product number Packaging Price Buy
FP70999 100g $228 Buy
FP70999 250g $520 Buy
FP70999 500g $845 Buy
CS-0030694 25g $136 Buy
CS-0030694 100g $435 Buy

5-Phenylpenta-2,4-dienoic acid Chemical Properties, Uses, Production

Uses

5-Phenyl-2,4-pentadienoic acid is used as Synthetic building block, anti-malarial agent.

Definition

ChEBI: 5-phenylpenta-2,4-dienoic acid is a member of styrenes.

Synthesis

Malonic acid

141-82-2

Cinnamaldehyde

104-55-2

5-PHENYLPENTA-2,4-DIENOIC ACID

1552-94-9

GENERAL METHODS: Synthesis of 5-phenylpent-2,4-dienoic acid (Scheme 1) followed the Knoevenagel condensation reaction. Cinnamaldehyde (0.01 mol) was dissolved with malonic acid (0.01 mol) in 1.12 mL of a solvent mixture of pyridine and piperidine (0.01 mol). The reaction mixture was heated to reflux until carbon dioxide gas stopped escaping. Upon completion of the reaction, the reaction solution was poured into a mixture containing 2N HCl and ice, and the precipitate precipitated was collected by filtration and recrystallized from pure water or a 3:1 water/ethanol solvent mixture. If no precipitate is produced, the aqueous phase is extracted with 3 x 100 mL of chloroform or dichloromethane, the organic phases are combined, dried with anhydrous magnesium sulfate, concentrated to dryness under reduced pressure, and the resulting residue is purified by recrystallization from aqueous ethanol.

References

[1] Molecules, 2014, vol. 19, # 7, p. 9655 - 9674
[2] Chemistry - A European Journal, 2017, vol. 23, # 3, p. 554 - 557
[3] Organic Letters, 2017, vol. 19, # 23, p. 6412 - 6415

5-Phenylpenta-2,4-dienoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 116)
Supplier Tel Email Country ProdList Advantage
Changzhou green chemical co., LTD 0519-82733646 13814799543 sales_01@salutchem.com China 108 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Shanghai Longsheng chemical Co.,Ltd. 58099637 13585536065 sales@shlschem.com China 9880 59
Dalian Meilun Biotech Co., Ltd. 0411-62910999 13889544652 sales@meilune.com China 4765 58
BioBioPha Co., Ltd. 0871-65217109 y.liu@mail.biobiopha.com China 5641 65
Shanghai TaoSu Biochemical Technology Co., Ltd. 021-33632979 info@tsbiochem.com China 8039 58

View Latest Price from 5-Phenylpenta-2,4-dienoic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Cinnamylideneacetic acid pictures 2026-04-22 Cinnamylideneacetic acid
1552-94-9
$29.00 99.75% 10g TargetMol Chemicals Inc.
5-PHENYLPENTA-2,4-DIENOIC ACID pictures 2025-04-04 5-PHENYLPENTA-2,4-DIENOIC ACID
1552-94-9
1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
5-Phenylpenta-2,4-dienoic acid pictures 2020-01-08 5-Phenylpenta-2,4-dienoic acid
1552-94-9
$1.00 1g Min98% HPLC Career Henan Chemical Co

5-Phenylpenta-2,4-dienoic acid Spectrum

5-phenyl-4-pentadienoicacid B-STYRYLACRYLIC ACID BETA-STYRYLACRYLIC ACID CINNAMYLIDENE ACETIC ACID AKOS B004062 4-PHENYL-1,3-BUTADIENE-1-CARBOXYLIC ACID 5-PHENYLPENTA-2,4-DIENOIC ACID, 98+% 5-Phenyl-2,4-pentadienoic acid, 98+% 2,4-Pentadienoic acid, 5-phenyl- 2,4-Pentadienoic acid, 5-phenyl- (van) (8ci)(9ci) Einecs 216-298-2 Nsc 109408 Nsc 1778 Nsc 63972 (2E,4E)-5-phenylpenta-2,4-dienoic acid BL 1255 Cinnamylideneacetic acid, 10 mM in DMSO 5-phenylpentyl-2,4-dieneacid 5-PHENYL-2,4-PENTADIENOIC ACID JUAREZIC ACID 5-Phenylpenta-2,4-dienoic acid 1552-94-9 C6H5CHCHCHCHCHCO2H Inhibitors Aromatic Phenylacetic Acids and Derivatives