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Methoxyverapamil hydrochloride

Methoxyverapamil hydrochloride Structure
Methoxyverapamil hydrochloride structure
CAS No.
16662-46-7
Chemical Name:
Methoxyverapamil hydrochloride
Synonyms
GALLOPAMIL;D600;D600, HCL;(S)-Gallopamil;D 600 HYDROCHLORIDE;GALLOPAMIL HYDROCHLORIDE;(+/-)-METHOXYVERAPAMIL HCL;Methoxyverapamil hydrochloride;Gallopamil HCl (Methoxyverapamil);(+/-)-METHOXYVERAPAMIL, HYDROCHLORIDE
CBNumber:
CB6780731
Molecular Formula:
C28H41ClN2O5
Molecular Weight:
521.09
MDL Number:
MFCD00058000
MOL File:
16662-46-7.mol
MSDS File:
SDS
Last updated:2026-09-12 18:54:24
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Methoxyverapamil hydrochloride Properties

Melting point 145-148°
storage temp. Store at -20°C
solubility DMF: 16.7 mg/ml; DMSO: 10 mg/ml; Ethanol: 10 mg/ml; PBS (pH 7.2): 0.25 mg/ml
form A crystalline solid
color White to off-white
FDA UNII VT4VR32A0T
ATC code C08DA02

SAFETY

Risk and Safety Statements

WGK Germany  3

Methoxyverapamil hydrochloride price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 24270 (±)-Methoxyverapamil (hydrochloride) ≥98% 16662-46-7 5mg $85 2026-04-30 Buy
Cayman Chemical 24270 (±)-Methoxyverapamil (hydrochloride) ≥98% 16662-46-7 10mg $145 2026-04-30 Buy
Cayman Chemical 24270 (±)-Methoxyverapamil (hydrochloride) ≥98% 16662-46-7 50mg $425 2026-04-30 Buy
Cayman Chemical 24270 (±)-Methoxyverapamil (hydrochloride) ≥98% 16662-46-7 100mg $680 2026-04-30 Buy
ChemScene CS-0109891 Gallopamil hydrochloride 98.10% 16662-46-7 5mg $97 2026-06-04 Buy
Product number Packaging Price Buy
24270 5mg $85 Buy
24270 10mg $145 Buy
24270 50mg $425 Buy
24270 100mg $680 Buy
CS-0109891 5mg $97 Buy

Methoxyverapamil hydrochloride Chemical Properties, Uses, Production

Description

Gallopamil hydrochloride is a somewhat more potent methoxy analog of calcium channel blocker verapamil with a similar profile. It is useful in the treatment of angina and auricular arrhythmia.

Originator

Knoll (W. Germany)

Uses

Gallopamil hydrochloride (Methoxyverapamil hydrochloride), a methoxy derivative of Verapamil, is a phenylalkylamine calcium antagonist[1]. Gallopamil hydrochloride inhibits acid secretion in a concentration-dependent manner with an IC50 of 10.9 μM[2]. Gallopamil hydrochloride is a potent antiarrhythmic and vasodilator agent[3].

brand name

Benpredil;Corapamil;PROCORUM.

in vivo

Gallopamil hydrochloride (Methoxyverapamil hydrochloride; i.v.; 0.2 mg/kg; for 5 min) markedly reduces ventricular tachycardia (VT) and totally prevents fibrillation (VF). Gallopamil significantly reduces systolic and diastolic blood pressure measured 5 min after injection without markedly influencing heart rate[3].

Animal Model:Male Wistar rats weighing 290-370 g[3]
Dosage:0.2 mg/kg
Administration:i.v.; 5 min
Result:Markedly reduced VT and totally prevented VF.

References

[1] Brogden RN, et al. Gallopamil. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in ischaemic heart disease. Drugs. 1994 Jan;47(1):93-115. DOI:10.2165/00003495-199447010-00007
[2] Sewing KF, et al. Calcium channel antagonists verapamil and gallopamil are powerful inhibitors of acid secretion in isolated and enriched guinea pig parietal cells. Pharmacology. 1983;27(1):9-14. DOI:10.1159/000137824
[3] Kirchengast M, et al. Reperfusion arrhythmias in closed-chest rats: the effect of myocardial noradrenaline depletion and Ca2(+)-antagonism. Clin Exp Pharmacol Physiol. 1991 Apr;18(4):217-21. DOI:10.1111/j.1440-1681.1991.tb01434.x

Methoxyverapamil hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Methoxyverapamil hydrochloride Suppliers

Global Suppliers ( 52)
Supplier Tel Email Country ProdList Advantage
Nanjing XiZe Biotechnology CO., Ltd. 025-66023220 15250997978 1511893459@qq.com China 4777 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
InvivoChem +1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6378 58
AFINE CHEMICALS LIMITED +86-571-85134551 +86-18958018566 info@afinechem.com China 15030 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
Shanghai hongqu biomedical technology co. LTD 88888888888 hongquchem@qq.com China 5123 58
cjbscvictory 13348960310 13348960310 3003867561@qq.com China 10233 58
Supplier Advantage
Nanjing XiZe Biotechnology CO., Ltd. 55
Shanghai EFE Biological Technology Co., Ltd. 58
Shanghai YuanYe Biotechnology Co., Ltd. 60
BOC Sciences 58
TargetMol Chemicals Inc. 58
InvivoChem 58
AFINE CHEMICALS LIMITED 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Shanghai hongqu biomedical technology co. LTD 58
cjbscvictory 58

View Latest Price from Methoxyverapamil hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Gallopamil hydrochloride pictures 2026-07-15 Gallopamil hydrochloride
16662-46-7
 $67.00-143.00 99.86% 10g TargetMol Chemicals Inc.
Gallopamil hydrochloride pictures 2026-07-15 Gallopamil hydrochloride
16662-46-7
 $67.00-143.00 99.86% 10g TargetMol Chemicals Inc.

Methoxyverapamil hydrochloride Spectrum

METHOXYVERAPAMIL HYDROCHLORIDE(16662-46-7)1HNMR

16662-46-7 (Methoxyverapamil hydrochloride) Related Search:

3,5-Dimethoxyphenylacetonitrile 3-Hydroxy-4-methoxyphenethylamine hydrochloride 3-tert-Butylphenol Methoxyverapamil hydrochloride Methoxy-(-)-verapamil hydrochloride
Devapamil Trimethylacetonitrile Hordenine hydrochloride 3-Methyl-2-(3,4-dimethoxyphenyl)butyronitrile (3-Methoxyphenyl)acetonitrile
3-Methylbutanenitrile 2-Ethyl-2-phenylbutyronitrile (3,4-Dimethoxyphenyl)acetonitrile 2-Ethyl-2-methylbutyronitrile 2-Isopropyl-2-phenylacetonitrile
5-tert-Butylpyrogallol (3,4-Dihydroxyphenyl)acetonitrile 2-Phenylbutyronitrile

1of4

(+/-)-VERAPAMIL, METHOXY-, HYDROCHLORIDE VERAPAMIL, (+/-)-METHOXY-, HYDROCHLORIDE (+/-)-ALPHA-(3-[(2-[3,4-DIMETHOXYPHENYL]ETHYL)METHYLAMINO]PROPYL)-3,4,5-TRIMETHOXY-ALPHA-(1-METHYLETHYL)-BENZENEACETONITRILE HYDROCHLORIDE D600 D600, HCL D 600 HYDROCHLORIDE [3-cyano-3-(3,4,5-trimethoxyphenyl)hex-6-yl]-(5,6-dimethoxyphenethyl)methylammonium chloride GALLOPAMIL HYDROCHLORIDE (S)-2-(3,4,5-Trimethoxyphenyl)-5-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]-2-(1-methylethyl)pentanenitrile (S)-Gallopamil (αS)-α-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4,5-trimethoxy-α-(1-methylethyl)benzeneacetonitrile (αS)-α-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-α-isopropyl-3,4,5-trimethoxybenzeneacetonitrile 5-((3,4-dimethoxyphenethyl)(methyl)amino)-2-isopropyl-2-(3,4,5-trimethoxyphenyl)pentanenitrile hydrochloride (+/-)-METHOXYVERAPAMIL HCL (+/-)-METHOXYVERAPAMIL, HYDROCHLORIDE Gallopamil HCl (Methoxyverapamil) Calcium Channel,Ca channels,Methoxyverapamil,vasodilator,calcium,antiarrhythmic,inhibit,Ca2+ channels,Gallopamil hydrochloride,Gallopamil,phenylalkylamine,Inhibitor,Verapamil (±)-Methoxyverapamil hydrochloride in methanol Gallopamil hydrochloride, 10 mM in DMSO GALLOPAMIL Methoxyverapamil hydrochloride 16662-46-7