METHOXY-(-)-VERAPAMIL HYDROCHLORIDE
- CAS No.
- 36622-40-9
- Chemical Name:
- METHOXY-(-)-VERAPAMIL HYDROCHLORIDE
- Synonyms
- (-)-D 600;(-)-Gallopamil;(-)-Methoxyverapamil;Gallopamil, ( ) ,Gallopamil, ();(-)-METHOXYVERAPAMIL HYDROCHLORIDE;METHOXY-(-)-VERAPAMIL HYDROCHLORIDE;(-)-VERAPAMIL, METHOXY-, HYDROCHLORIDE;Benzeneacetonitrile, α-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4,5-trimethoxy-α-(1-methylethyl)-, (αS)-
- CBNumber:
- CB3393460
- Molecular Formula:
- C28H40N2O5
- Molecular Weight:
- 484.63
- MDL Number:
- MFCD00069306
- MOL File:
- 36622-40-9.mol
Boiling point | 605.9±55.0 °C(Predicted) |
---|---|
Density | 1.068±0.06 g/cm3(Predicted) |
solubility | H2O: soluble |
pka | 8.96±0.50(Predicted) |
FDA UNII | 5X7S7C93QM |
METHOXY-(-)-VERAPAMIL HYDROCHLORIDE Chemical Properties,Uses,Production
Uses
(-)-Gallopamil exerts a selective modulation of the fast voltage-dependent inactivation. (-)-Gallopamil inhibits efficiently Cav1.2 constructs formed by β-subunits (promoting fast voltage-dependent inactivation). (-)-Gallopamil also accelerates the voltage-dependent phase of ICa decay (as well as the voltage-dependent decay of Ba2+ currents). (-)-Gallopamil is promising for research of antiarrhythmics[1][2].
References
[1] Sokolov S, et al. On the role of Ca(2+)- and voltage-dependent inactivation in Ca(v)1.2 sensitivity for the phenylalkylamine (-)gallopamil. Circ Res. 2001 Oct 12;89(8):700-8. DOI:10.1161/hh2001.098983
[2] Sokolov S, et al. Inactivation determinant in the I-II loop of the Ca2+ channel alpha1-subunit and beta-subunit interaction affect sensitivity for the phenylalkylamine (-)gallopamil. J Physiol. 1999 Sep 1;519 Pt 2(Pt 2):315-22. DOI:10.1111/j.1469-7793.1999.0315m.x
METHOXY-(-)-VERAPAMIL HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
METHOXY-(-)-VERAPAMIL HYDROCHLORIDE Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32431 | 58 |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 19960 | 58 |
TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29519 | 58 |
Supplier | Advantage |
---|---|
TargetMol Chemicals Inc. | 58 |
Hangzhou MolCore BioPharmatech Co.,Ltd. | 58 |
TargetMol Chemicals Inc. | 58 |
TargetMol Chemicals Inc. | 58 |
View Lastest Price from METHOXY-(-)-VERAPAMIL HYDROCHLORIDE manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2025-08-21 | Gallopamil, (-)-
36622-40-9
|
US $1980.00-1520.00 / mg | 10g | TargetMol Chemicals Inc. |
-
- Gallopamil, (-)-
36622-40-9
- US $1980.00-1520.00 / mg
- TargetMol Chemicals Inc.
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