1-(4-Bromo-phenyl)-cyclopropylamine
- CAS No.
- 345965-54-0
- Chemical Name:
- 1-(4-Bromo-phenyl)-cyclopropylamine
- Synonyms
- 1-(4-bromophenyl)cyclopropan-1-amine;1-(4-BROMOPHENYL)CYCLOPROPANAMINE;1-(4-Bromo-phenyl)-cyclopropylamine;Cyclopropanamine, 1-(4-bromophenyl)-;1-(4-BROMOPHENYL)CYCLOPROPANAMINE HCL;1-(4-BROMO-PHENYL)-CYCLOPROPYLAMINE ISO 9001：2015 REACH
- CBNumber:
- CB6841593
- Molecular Formula:
- C9H10BrN
- Molecular Weight:
- 212.09
- MDL Number:
- MFCD07374473
- MOL File:
- 345965-54-0.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H312-H335-H319-H302-H332 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P312-P280-P302+P352-P312-P322-P363-P501 |
1-(4-Bromo-phenyl)-cyclopropylamine price More Price(49)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS26691-A | 1-(4-Bromophenyl)cyclopropan-1-amine 98% | 345965-54-0 | 1g | $214 | 2026-06-04 | Buy |
| Activate Scientific | AS26691-A | 1-(4-Bromophenyl)cyclopropan-1-amine 98% | 345965-54-0 | 5g | $589 | 2026-06-04 | Buy |
| Synthonix | B23185 | 1-(4-bromophenyl)cyclopropan-1-amine 97.0% | 345965-54-0 | 100mg | $25 | 2026-05-06 | Buy |
| Synthonix | B23185 | 1-(4-bromophenyl)cyclopropan-1-amine 97.0% | 345965-54-0 | 250mg | $40 | 2026-05-06 | Buy |
| Synthonix | B23185 | 1-(4-bromophenyl)cyclopropan-1-amine 97.0% | 345965-54-0 | 1g | $60 | 2026-05-06 | Buy |
1-(4-Bromo-phenyl)-cyclopropylamine Chemical Properties, Uses, Production
Uses
1-(4-bromobenzene)cyclopropylamine is an amine compound that can be used as a pharmaceutical synthesis intermediate.
Synthesis
623-00-7
925-90-6
345965-54-0
General Method G: Cyclopropanation Reaction (0459) Ethylmagnesium bromide (3.0 M ethyl ether solution, 1.1 eq.) was added slowly and dropwise to a stirred mixture of arylonitrile (1 eq.) and tetraisopropoxytitanium (1.7 eq.) at -70 °C. The reaction mixture was gradually warmed to 25 °C and stirred continuously for 1 hour. Subsequently, boron trifluoride ethyl ether complex (3 eq.) was added dropwise to the reaction system at 25 °C. After the dropwise addition was completed, stirring of the reaction mixture was continued for 2 hours. After completion of the reaction, the reaction was quenched with 2M aqueous hydrochloric acid. Next, the pH of the reaction solution was adjusted to alkaline with 2M aqueous sodium hydroxide solution. The organic material in the reaction solution was extracted with ether. The organic layers were combined, dried with anhydrous sodium sulfate, filtered and concentrated. The crude product was purified by silica gel column chromatography (eluent: petroleum ether/ethyl acetate, ratio from 10:1 to 1:1 gradient elution) to obtain the target product 1-arylcyclopropylamine. Example 64: Synthesis of quinuclidinyl cyclic-3-yl 1-(biphenyl-4-yl)cyclopropyl carbamate 4-Bromobenzonitrile (3.00 g, 16.5 mmol) was converted to 1-(4-bromophenyl)cyclopropylamine (1.80 g, 51% yield) according to General Method G. The product was a yellow solid.
References
[1] Patent: US9126993, 2015, B2. Location in patent: Page/Page column 49; 87
[2] Patent: WO2016/145046, 2016, A1. Location in patent: Page/Page column 64; 65; 70; 71
1-(4-Bromo-phenyl)-cyclopropylamine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Wuhan ariel chemical Co., LTD. | 18986259541 18986259541 | sales@3stc.com | China | 3829 | 58 |
| Chengdu Forest Science and Technology Development Co., Ltd. | 18030648795 18030648795 | sales@cdforestchem.com | China | 1998 | 58 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 13913916777 | cfzhang@aikonchem.com | China | 19902 | 55 |
| SuZhou ShiYa Biopharmaceuticals, Inc. | 86(512)5235 8471 17715136450 | sales@shiyabiopharm.com | China | 4167 | 58 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 18201 | 56 |
| Wuhan Kaymke Chemical Co., Ltd., | 027-87342388 18086026008 | sales@kaymke.com | China | 3537 | 55 |
View Latest Price from 1-(4-Bromo-phenyl)-cyclopropylamine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-09 | 1-(4-BROMO-PHENYL)-CYCLOPROPYLAMINE
345965-54-0
|
$1.00 | 1KG | 99% | 200kg | Career Henan Chemical Co |
-
- 1-(4-BROMO-PHENYL)-CYCLOPROPYLAMINE
345965-54-0
- $1.00
- 99%
- Career Henan Chemical Co
