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Estradiol hemihydrate

CAS No.
35380-71-3
Chemical Name:
Estradiol hemihydrate
Synonyms
Estradiol (1250008);Estradiol Hemihydrates;EESTRADIOL HEMIHYDRATE;Estradiol Hemihydrate EP;17β-Estradiol hemihydrate;beta-Estradiol semihydrate;Estradiol Hemihydrate USP36;BETA-OESTRADIOL VETRANAL, 250 MG;Estriol EP Impurity D as Hemihydate;Ethinylestradiol EP Impurity D as Hemihydrate
CBNumber:
CB6971652
Molecular Formula:
C18H24O2.H2O
Molecular Weight:
290.4
MDL Number:
MFCD23102821
MOL File:
35380-71-3.mol
MSDS File:
SDS
Last updated:2026-05-28 02:05:22

Estradiol hemihydrate Properties

storage temp. 2-8°C
form powder
BRN 1914275
Major Application pharmaceutical
pharmaceutical small molecule
InChI InChI=1/C18H24O2.H2O/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20;/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3;1H2/t14,15-,16,17-,18+;/s3
InChIKey QJNCGXGNKJUDEM-KEFFNRLXNA-N
SMILES C12CC[C@@H](O)[C@@]1(C)CCC1C3C=CC(O)=CC=3CC[C@@]21[H].O |&1:3,5,19,r|
FDA UNII CXY7B3Q98Z
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Health Hazard (GHS08)Environment (GHS09)
GHS08,GHS09
Signal word  Danger
Hazard statements  H351-H360FD-H362-H410
Precautionary statements  P202-P260-P263-P264-P273-P308+P313
Hazard Codes  T
Risk Statements  60-63-40-64
Safety Statements  53-36/37-45
WGK Germany  3
HS Code  2937230000
Storage Class 6.1D - Non-combustible acute toxic Cat.3
toxic hazardous materials or hazardous materials causing chronic effects
Hazard Classifications Aquatic Acute 1
Aquatic Chronic 1
Carc. 2
Lact.
Repr. 1A

Estradiol hemihydrate price More Price(18)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich E1620000 Estradiol hemihydrate European Pharmacopoeia (EP) Reference Standard 35380-71-3 100 mg $254 2026-04-30 Buy
Sigma-Aldrich BP729 Estradiol hemihydrate British Pharmacopoeia (BP) Assay Standard 35380-71-3 100MG $242 2026-04-30 Buy
Sigma-Aldrich E1620000 Estradiol hemihydrate European Pharmacopoeia (EP) Reference Standard 35380-71-3 e1620000 $220 2024-03-01 Buy
Biosynth FE31861 Estradiol hemihydrate 35380-71-3 1g $250 2026-06-04 Buy
Biosynth FE31861 Estradiol hemihydrate 35380-71-3 0.5g $250 2026-06-04 Buy
Product number Packaging Price Buy
E1620000 100 mg $254 Buy
BP729 100MG $242 Buy
E1620000 e1620000 $220 Buy
FE31861 1g $250 Buy
FE31861 0.5g $250 Buy

Estradiol hemihydrate Chemical Properties, Uses, Production

Uses

Estradiol hemihydrate is a useful research chemical compound.

Uses

Estradiol hemihydrate (CAS# 35380-71-3) is a useful research chemical compound. It is used in methods of contraception using nomegestrol acetate and estradiol.

in vivo

Estradiol hemihydrate (1 nM, the hippocampal slices from FBN-ARO-KO mice) rescues long-term potentiation (LTP) amplitude[1]. Estradiol hemihydrate (0.0167 mg, implanted s.c., FBN-ARO-KO mice) rescues the molecular and functional deficits in FBN-ARO-KO mice[1].

Animal Model:FBN-ARO-KO Mice[2]
Dosage:1 nM
Administration:Treated for the hippocampal slices
Result:Rescued long-term potentiation (LTP) amplitude of both male and female mice.
Animal Model:FBN-ARO-KO Mice[2]
Dosage:0.0167 mg
Administration:Alzet minipumps with Estradiol (implanted s.c.), examined 7 days after minipump implantation.
Result:Restored hippocampal and cortical E2 levels to 93%, phosphorylation of AKT, ERK and CREB in the hippocampus and cortex to 90-95%, BDNF level to 80-90%, restored both synaptophysin and PSD95 in the forebrain. Rescued the spatial learning and memory defects.

Estradiol hemihydrate Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 110)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Tianjin heowns Biochemical Technology Co., Ltd. 400 638 7771 sales@heowns.com China 14412 57
Sinopharm Chemical Reagent Co,Ltd. 86-21-63210123 sj_scrc@sinopharm.com China 9791 79
Shanghai T&W Pharmaceutical Co., Ltd. +86 21 61551611 China 9874 58
GIHI CHEMICALS CO.,LTD 0086-571-86217390 Sales@gihichem.com China 858 58
Credit Asia Chemical Co., Ltd. +86 (21) 61124340 China 9739 58
Chizhou Kailong Import and Export Trade Co., Ltd. xg01_gj@163.com China 9413 50
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51389 80
Watson Biotechnology Co.,Ltd 027-59207879 1972026995 18140587686 sales@3600chem.com China 4175 55
Shanghai Rechem science Co., Ltd. 021-31433387 15618786686 sales@rechemscience.com China 2968 58

View Latest Price from Estradiol hemihydrate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Estradiol hemihydrate pictures 2026-09-18 Estradiol hemihydrate
35380-71-3
100g 97.0% ~ 103.0%; EP9.5 250kg/month WUHAN FORTUNA CHEMICAL CO., LTD
Estradiol hemihydrate pictures 2026-09-17 Estradiol hemihydrate
35380-71-3
1Gram 98% 50KG Hangzhou Hyper Chemicals Limited
Estradiol Hemihydrates pictures 2026-05-28 Estradiol Hemihydrates
35380-71-3
$10.00 1KG 98% 10 ton Hebei Chuanghai Biotechnology Co,.LTD
BETA-OESTRADIOL VETRANAL, 250 MG beta-Estradiol semihydrate Estra-1,3,5(10)-triene-3,17-diol(17b)-, hydrate (2:1) (8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol,hydrate EESTRADIOL HEMIHYDRATE Estradiol Hemihydrates Estradiol hemihydrateQ: What is Estradiol hemihydrate Q: What is the CAS Number of Estradiol hemihydrate Q: What is the storage condition of Estradiol hemihydrate Estradiol (1250008) Estradiol Benzoate EP Impurity A as Hemihydrate Estradiol Valerate EP Impurity A as Hemihydrate Estriol EP Impurity D as Hemihydate Ethinylestradiol EP Impurity D as Hemihydrate 17β-Estradiol hemihydrate 17β-Oestradiol hemihydrate|||17β-Estradiol hemihydrate|||β-Estradiol hemihydrate 17β-Oestradiol hemihydrate|||β-Estradiol hemihydrate Estradiol Hemihydrate EP Estradiol Hemihydrate USP36 Estradiol Hemihydrate (17beta-Estradiol Hemihydrate) 1.0 mg/ml in Acetonitrile (anhydrous substance) 35380-71-3 2C18H24O2H2O