3-(Hydroxymethyl)-1-adamantol
- CAS No.
- 38584-37-1
- Chemical Name:
- 3-(Hydroxymethyl)-1-adamantol
- Synonyms
- 3-hydroxyadamantylmethanol;1-Hydroxy-3-adamantylmethanol;3-(Hydroxymethyl)-1-adamantol;3-Hydroxymethyl-1-adamantanol;3-Hydroxy-1-Adamantanemethanol;3-(Hydroxymethyl)-1-Adamantantol;3-Hydroxy-1-adamantanemethanol 98%;3-Hydroxy-1-hydroxyMethyladMantane;3-(Hydroxymethyl)-1-adamantanol>3-hydroxy-1-hydroxyMethyladaMantane
- CBNumber:
- CB6972806
- Molecular Formula:
- C11H18O2
- Molecular Weight:
- 182.26
- MDL Number:
- MFCD03105096
- MOL File:
- 38584-37-1.mol
- MSDS File:
- SDS
| Melting point | 158-162 °C |
|---|---|
| Boiling point | 322.6±10.0 °C(Predicted) |
| Density | 1.261±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 15.04±0.10(Predicted) |
| form | Powder |
| color | White to pale brown |
| InChI | InChI=1S/C11H18O2/c12-7-10-2-8-1-9(3-10)5-11(13,4-8)6-10/h8-9,12-13H,1-7H2 |
| InChIKey | FORAJDRXEYKDFJ-UHFFFAOYSA-N |
| SMILES | C12(CO)CC3CC(CC(O)(C3)C1)C2 |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H318 | |||||||||
| Precautionary statements | P280-P305+P351+P338 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 41 | |||||||||
| Safety Statements | 26-39 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29061990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Dam. 1 | |||||||||
| NFPA 704 |
|
3-(Hydroxymethyl)-1-adamantol price More Price(51)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 679968 | 3-(Hydroxymethyl)-1-adamantol 97% | 38584-37-1 | 1g | $92.8 | 2023-01-07 | Buy |
| TCI Chemical | H1415 | 3-(Hydroxymethyl)-1-adamantanol >98.0%(GC) | 38584-37-1 | 1g | $29 | 2026-04-30 | Buy |
| TCI Chemical | H1415 | 3-(Hydroxymethyl)-1-adamantanol >98.0%(GC) | 38584-37-1 | 5g | $87 | 2026-04-30 | Buy |
| Biosynth | FH14755 | 3-(Hydroxymethyl)-1-adamantol | 38584-37-1 | 10g | $900 | 2026-06-04 | Buy |
| Biosynth | FH14755 | 3-(Hydroxymethyl)-1-adamantol | 38584-37-1 | 100g | $900 | 2026-06-04 | Buy |
3-(Hydroxymethyl)-1-adamantol Chemical Properties, Uses, Production
Uses
3-Hydroxy-1-adamantyl methanol can be used to introduce adamantyl groups into the structure of target organic molecules. In organic synthesis methodology, it is mainly used for the structural modification and synthesis of sterically hindered organic ligands.
Chemical Properties
White solid
Synthesis
770-71-8
38584-37-1
42711-75-1
General procedure for the synthesis of 3-hydroxy-1-adamantanemethanol and 3-hydroxyadamantane from 1-adamantanemethanol: Under vigorous stirring, adamantan-1-ylmethanol (1a-1d) was added in batches over a period of 5-10 minutes to 15-20°C fuming nitric acid. The resulting solution was stirred vigorously for 1 h at 20°C and poured into 500 g of crushed ice. The product was extracted with butan-1-ol (6 mL), the organic layer was separated, 20 mL of hydrazine hydrate was added and the mixture was refluxed for 3 hours. After cooling, the mixture was diluted with 10 mL of butan-1-ol and washed sequentially with water (2 x 20 mL), 5% aqueous potassium hydroxide (3 x 15 mL) and water (2 x 10 mL). The organic phase was dried and evaporated under reduced pressure and the residue was recrystallized from toluene. The basic washings were acidified with aqueous HCl and the precipitated 3-hydroxyadamantane-1-carboxylic acid (5a-5d) was filtered. (3-Hydroxyadamantan-1-yl)methanol (4a) was synthesized from 2 g (0.012 mol) of 1a and 20 mL of fuming nitric acid in a yield of 1.6 g (75%) with a melting point of 140-142°C; literature value [50]: melting point 139-141°C. 3-Hydroxyadamantane-1-carboxylic acid (5a) was synthesized in a yield of 0.18 g (8%) with a melting point 203-205°C; literature value [64]: melting point 202-203 °C.
References
[1] Russian Journal of Organic Chemistry, 2018, vol. 54, # 9, p. 1294 - 1300
[2] Zh. Org. Khim., 2018, vol. 54, # 9, p. 1283 - 1289,8
3-(Hydroxymethyl)-1-adamantol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sichuan Zhongbang Pharma CO.，LTD | 0830-0830-2585019 13679670161 | sales2@zhongbangst.com | China | 105 | 69 |
| Chongqing Maohuan Chemical Co.Ltd> | 13996103726 | info@bschem.com | China | 172 | 58 |
| Zhangjiagang Xikai Chemical Co.,Ltd | 051255701600 13962289590 | sales@xikaichem.com | China | 311 | 58 |
| Shanghai AMINO Biotechnology Co., Ltd | 17302153218 | 1743952078@qq.com | China | 220 | 58 |
| Suzhou Zhuo Xinya Technology Co., LTD | 18506228039 | 3640548236@qq.com | China | 1302 | 58 |
| Huzhou Chenxi Environmental Protection Technology Co., Ltd. | 16762203950 16762203950 | 3775386035@qq.com | China | 102 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shijiazhuang Sdyano Fine Chemical Co., Ltd. | 0311-89250318 13582355795 | master@sjzsdyn.com | China | 2776 | 65 |
View Latest Price from 3-(Hydroxymethyl)-1-adamantol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-30 | 3-(Hydroxymethyl)-1-adamantol
38584-37-1
|
1kg | 98% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2025-04-04 | 3-(Hydroxymethyl)-1-adamantol
38584-37-1
|
1KG | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | ||
 |
2020-11-17 | 3-(Hydroxymethyl)-1-adamantol
38584-37-1
|
$20.00 | 1KG | 99% | 1000kg | Longyan Tianhua Biological Technology Co., Ltd |
-
- 3-(Hydroxymethyl)-1-adamantol
38584-37-1
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- 3-(Hydroxymethyl)-1-adamantol
38584-37-1
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 3-(Hydroxymethyl)-1-adamantol
38584-37-1
- $20.00
- 99%
- Longyan Tianhua Biological Technology Co., Ltd
