ChemicalBook >> CAS DataBase List >>9H-Purine-9-ethanamine, 6-amino-N-(2,2-dimethylpropyl)-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-

9H-Purine-9-ethanamine, 6-amino-N-(2,2-dimethylpropyl)-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-

9H-Purine-9-ethanamine, 6-amino-N-(2,2-dimethylpropyl)-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]- structure

CAS No.: 1000999-96-1

Chemical Name:: 9H-Purine-9-ethanamine, 6-amino-N-(2,2-dimethylpropyl)-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-

Synonyms: Icapamespib;PU-HZ151;Icapamespib (Synonyms: PU-HZ151);8-((6-Iodobenzo[d][1,3]dioxol-5-yl)thio)-9-(2-(neopentylamino)ethyl)-9H-purin-6-amine;9H-Purine-9-ethanamine, 6-amino-N-(2,2-dimethylpropyl)-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-;6-Amino-N-(2,2-dimethylpropyl)-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-9H-purine-9-ethanamine (ACI);9-{2-[(2,2-dimethylpropyl)amino]ethyl}-8-[(6-iodo-2H-1,3-benzodioxol-5-yl)sulfanyl]-9H-purin-6-amine

CBNumber:: CB69787391

Molecular Formula:: C19H23IN6O2S

Molecular Weight:: 526.39

MDL Number:

MOL File:: 1000999-96-1.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-08-05 09:01:00

Request For Quotation

9H-Purine-9-ethanamine, 6-amino-N-(2,2-dimethylpropyl)-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]- Properties

Boiling point	648.4±65.0 °C(Predicted)
Density	1.76±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
form	Solid
pka	9.76±0.19(Predicted)
color	White to off-white
FDA UNII	447591A1PU

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319
Precautionary statements	P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

9H-Purine-9-ethanamine, 6-amino-N-(2,2-dimethylpropyl)-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]- price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0138643	Icapamespib 99.60%	1000999-96-1	5mg	$379	2026-06-04	Buy
ChemScene	CS-0138643	Icapamespib 99.60%	1000999-96-1	10mg	$596	2026-06-04	Buy
ChemScene	CS-0138643	Icapamespib 99.60%	1000999-96-1	25mg	$1246	2026-06-04	Buy
ChemScene	CS-0138643	Icapamespib 99.60%	1000999-96-1	50mg	$2221	2026-06-04	Buy
ChemScene	CS-0138643	Icapamespib 99.60%	1000999-96-1	100mg	$3553	2026-06-04	Buy

Product number	Packaging	Price	Buy
CS-0138643	5mg	$379	Buy
CS-0138643	10mg	$596	Buy
CS-0138643	25mg	$1246	Buy
CS-0138643	50mg	$2221	Buy
CS-0138643	100mg	$3553	Buy

9H-Purine-9-ethanamine, 6-amino-N-(2,2-dimethylpropyl)-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]- Chemical Properties, Uses, Production

Uses

Icapamespib (PU-HZ151) is a potent HSP90 inhibitor with an EC50 of 5nM. Icapamespib is able to cross blood-brain barrier[1].

References

[1] Bolaender A, et al. Chemical tools for epichaperome-mediated interactome dysfunctions of the central nervous system. Nat Commun. 2021;12(1):4669. Published 2021 Aug 3. DOI:10.1038/s41467-021-24821-2

9H-Purine-9-ethanamine, 6-amino-N-(2,2-dimethylpropyl)-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]- Preparation Products And Raw materials

Raw materials

Preparation Products

9H-Purine-9-ethanamine, 6-amino-N-(2,2-dimethylpropyl)-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]- Suppliers

Global Suppliers ( 13)

Supplier	Tel	Email	Country	ProdList	Advantage
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	9920	65
Shanghai YuanYe Biotechnology Co., Ltd.	15026964105	2881489226@qq.com	China	89667	60
Jilin Province Woda Biotechnology Co., Ltd.	13504435624	1927928688@qq.com	China	1644	58
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd	15317229551	15151849396@163.com	China	959	58
Zhengzhou convergence chemical co., LTD	037155153829 18003835034	3897192574@qq.com	China	9982	58
Bide Pharmatech Ltd.	400-1647117 13681763483	product02@bidepharm.com	China	59929	58
Nantong QuanYi Biotechnology Co., Ltd	0513-66337626 18051384581	sales@chemhifuture.com	China	5985	58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd	4000862158 18117107507	vip@med-life.cn	China	4999	58
RD International Technology Co., Limited	18024082417	market@ubiochem.com	China	9831	58
Aikon International Limited	025-58859352 18651614124	2881516338@qq.com	China	9968	58

Supplier	Advantage
BOC Sciences	65
Shanghai YuanYe Biotechnology Co., Ltd.	60
Jilin Province Woda Biotechnology Co., Ltd.	58
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd	58
Zhengzhou convergence chemical co., LTD	58
Bide Pharmatech Ltd.	58
Nantong QuanYi Biotechnology Co., Ltd	58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd	58
RD International Technology Co., Limited	58
Aikon International Limited	58

9H-Purine-9-ethanamine, 6-amino-N-(2,2-dimethylpropyl)-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]- Spectrum

9H-Purine-9-ethanamine, 6-amino-N-(2,2-dimethylpropyl)-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-(1000999-96-1)¹HNMR

1000999-96-1 (9H-Purine-9-ethanamine, 6-amino-N-(2,2-dimethylpropyl)-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-) Related Search:

PU-H71 Hydrate 9H-Purine-9-propanamine, 6-amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-, hydrochloride (1:1) 6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine 9H-Purine-9-ethanamine, 6-amino-N-(2,2-dimethylpropyl)-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]- 9H-Purine-9-ethanamine, 6-amino-N-(2,2-dimethylpropyl)-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-, hydrochloride (1:2)

9H-Purin-6-amine, 8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-9-(4-pentyn-1-yl)-

1of2

9H-Purine-9-ethanamine, 6-amino-N-(2,2-dimethylpropyl)-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]- Icapamespib (Synonyms: PU-HZ151) PU-HZ151 8-((6-Iodobenzo[d][1,3]dioxol-5-yl)thio)-9-(2-(neopentylamino)ethyl)-9H-purin-6-amine 9-{2-[(2,2-dimethylpropyl)amino]ethyl}-8-[(6-iodo-2H-1,3-benzodioxol-5-yl)sulfanyl]-9H-purin-6-amine Icapamespib 6-Amino-N-(2,2-dimethylpropyl)-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-9H-purine-9-ethanamine (ACI) 1000999-96-1 C19H23IN6O2S