TRIPTRIOLIDE
- CAS No.
- 137131-18-1
- Chemical Name:
- TRIPTRIOLIDE
- Synonyms
- TRIPTRIOLIDE
- CBNumber:
- CB6983402
- Molecular Formula:
- C20H26O7
- Molecular Weight:
- 378.41624
- MDL Number:
- MOL File:
- 137131-18-1.mol
TRIPTRIOLIDE Chemical Properties, Uses, Production
Uses
Triptriolide inhibits Puromycin aminonucleoside PAN (HY-15695)-induced apoptosis in mouse podocytes through regulation of Bcl-2 family proteins and inhibition of Caspase-3. Triptriolide promotes the cell survival, protects and restores the podocyte function through activation of TAK1-NF-κB signaling pathway and upregulation of podocin[1].
Definition
ChEBI: Triptriolide is an abietane diterpenoid with formula C20H26O7, originally isolated from Tripterygium wilfordii. It has a role as a plant metabolite and an anti-inflammatory agent. It is a gamma-lactone, a triol, an epoxide and an abietane diterpenoid.
References
[1] Yang YQ, et al., Dual-function of triptriolide in podocytes injury: inhibiting of apoptosis and restoring of survival. Biomed Pharmacother. 2019 Jan;109:1932-1939. DOI:10.1016/j.biopha.2018.11.031
TRIPTRIOLIDE Preparation Products And Raw materials
Raw materials
Preparation Products
TRIPTRIOLIDE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7717 | 56 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Chengdu Push Bio-Technology Co., Ltd. | 028-85370565-229 18080489829 | 18080489829@163.com | China | 8379 | 60 |
| BioBioPha Co., Ltd. | 0871-65217109 | y.liu@mail.biobiopha.com | China | 2793 | 58 |
| Shanghai Binsui Biotechnology Co., Ltd. | 18301908279 | 1292752157@qq.com | China | 7684 | 58 |
| Sichuan BioCrick Biotech Co., Ltd | 28-86-28-8543-3893 13260669172 | sales@biocrick.com | China | 5020 | 58 |
| TargetMol | 400-821-0310 15002144251 | xuexiang.shao@tsbiochem.com | China | 29128 | 58 |
