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TROXACITABINE

TROXACITABINE Structure
TROXACITABINE structure
CAS No.
145918-75-8
Chemical Name:
TROXACITABINE
Synonyms
CS-150;L-Oddc;SPD 758;Bch 4556;(-)-Occc;Troxatyl;(-)-Bch 204;TROXACITABINE;α-L-Dioxolane-C;Lamivudine Impurity I
CBNumber:
CB71011675
Molecular Formula:
C8H11N3O4
Molecular Weight:
213.19
MDL Number:
MFCD00871100
MOL File:
145918-75-8.mol
MSDS File:
SDS
Last updated:2025-07-14 15:27:00
Product description Number Pack Size Price
Troxacitabine T805580 0.5mg $335
Troxacitabine T805580 2.5mg $1490
Troxacitabine 296507 10mg $3787
TROXACITABINE 95.00% API0005342 1G $8805.3
TROXACITABINE 95.00% API0005342 10MG $1067.22
More product size
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TROXACITABINE Properties

Melting point 176-177°
alpha D25 -38.33° (c = 0.43 in MeOH).
Boiling point 422.5±55.0 °C(Predicted)
Density 1.71±0.1 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
solubility DMSO (Slightly), Methanol (Slightly)
pka 14.83±0.10(Predicted)
form Solid
color White to Off-White
Stability Hygroscopic
InChI InChI=1S/C8H11N3O4/c9-5-1-2-11(8(13)10-5)6-4-14-7(3-12)15-6/h1-2,6-7,12H,3-4H2,(H2,9,10,13)/t6-,7-/m0/s1
InChIKey RXRGZNYSEHTMHC-BQBZGAKWSA-N
SMILES C1(=O)N([C@@H]2CO[C@H](CO)O2)C=CC(N)=N1
EWG's Food Scores 1
FDA UNII 60KQZ0388Y
NCI Dictionary of Cancer Terms troxacitabine
NCI Drug Dictionary troxacitabine

TROXACITABINE price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC T805580 Troxacitabine 145918-75-8 0.5mg $335 2021-12-16 Buy
TRC T805580 Troxacitabine 145918-75-8 2.5mg $1490 2021-12-16 Buy
Usbiological 296507 Troxacitabine 145918-75-8 10mg $3787 2021-12-16 Buy
American Custom Chemicals Corporation API0005342 TROXACITABINE 95.00% 145918-75-8 1G $8805.3 2021-12-16 Buy
American Custom Chemicals Corporation API0005342 TROXACITABINE 95.00% 145918-75-8 10MG $1067.22 2021-12-16 Buy
Product number Packaging Price Buy
T805580 0.5mg $335 Buy
T805580 2.5mg $1490 Buy
296507 10mg $3787 Buy
API0005342 1G $8805.3 Buy
API0005342 10MG $1067.22 Buy

TROXACITABINE Chemical Properties,Uses,Production

Uses

Troxacitabine is a nucleoside analogue with potential anticancer activity. Troxacitabine have been studied in patients with refractory lymphoproliferative diseases.

Definition

ChEBI: Troxacitabine is a nucleobase-containing molecular entity and a carbohydrate derivative.

in vivo

Troxacitabine is highly active against the Panc-01 model, with TGI levels of 88.5% and 84.3% at the 10 and 25 mg/kg doses, respectively. The mean final tumor weights for animals given troxacitabine are also significantly smaller compared with vehicle controls. Troxacitabine has less activity against the MiaPaCa model[3]. Troxacitabine is very effective in human RCC tumor xenograft models, including CAM-i, A498, RXF-393, and SN12C carcinomas. Very good responses are ob served in animals bearing CAM-i, A498, and RXF-393 RCC tumors given i.p. doses of 10, 25, and 50 mg/kg twice a day for 5 days[2].

TROXACITABINE Preparation Products And Raw materials

Raw materials

Preparation Products

TROXACITABINE Suppliers

Global( 93)Suppliers
Supplier Tel Email Country ProdList Advantage
Standardpharm Co. Ltd. 		86-714-3992388 overseasales1@yongstandards.com United States 14332 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49977 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29795 58
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32470 58
Hubei Ipure Biology Co., Ltd 		+8613367258412 ada@ipurechemical.com China 10236 58
Hangzhou Huarong Pharm Co., Ltd. 		571-86758373 +8613588754946 sales@huarongpharm.com CHINA 3148 58
NewCan Biotech Limited 		+86-0571-86912261 +8613735419629 sales@newcanbio.com China 9985 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525 masar@topule.com China 8467 58
HANGZHOU LEAP CHEM CO., LTD. 		+86-571-87711850 market18@leapchem.com China 43333 58
Zhengzhou Chemprize Biotech Co., Ltd. 		+86-86-0371-56768238 +8615981919713 sales@chemprize.com China 297 58
Supplier Advantage
Standardpharm Co. Ltd. 		58
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
TargetMol Chemicals Inc. 		58
Hubei Ipure Biology Co., Ltd 		58
Hangzhou Huarong Pharm Co., Ltd. 		58
NewCan Biotech Limited 		58
Wuhan Topule Biopharmaceutical Co., Ltd 		58
HANGZHOU LEAP CHEM CO., LTD. 		58
Zhengzhou Chemprize Biotech Co., Ltd. 		58

View Lastest Price from TROXACITABINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-amino-1-((2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl)pyrimidin-2(1H)-one pictures 2021-09-18 4-amino-1-((2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl)pyrimidin-2(1H)-one
145918-75-8
 US $0.00-0.00 / mg 10mg 99% 10KG Hangzhou Huarong Pharm Co., Ltd.
TROXACITABINE pictures 2020-01-05 TROXACITABINE
145918-75-8
 US $1.00 / KG 1KG 95--99% 1ton Career Henan Chemical Co
  • TROXACITABINE pictures
  • TROXACITABINE
    145918-75-8
  • US $1.00 / KG
  • 95--99%
  • Career Henan Chemical Co

TROXACITABINE Spectrum

TROXACITABINE(145918-75-8)1HNMR

145918-75-8(TROXACITABINE)Related Search:

4-amino-1-((2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one Cytosine lamivudine sulfoxide Salicylic acid Lamivudine
Aids004768 Lamivudine EP Impurity A Gemcitabine lignocaine N-oxide 4-(HYDROXYMETHYL)BENZONITRILE
(2R,5R)-5-Hydroxy-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester Lamivudine Impurity 9 Lamivudine impurity 6 (1r,2s,5r)-2-Isopropyl-5-Methylcyclohexyl-5-Hydroxy-1,3oxathiolane-2-Carboxylate Antazoline
Uracil ent-LaMivudine Lamivudine EP Impurity B

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TROXACITABINE TROXACITABINE,2(1H)-PYRIMIDINONE, 4-AMINO-1-(2-(HYDROXYMETHYL)-1,3-DIOXOLAN-4-YL)-, (2S-CIS)- 4-Amino-1-[(2S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl]pyrimidin-2-one (-)-Bch 204 CS-150 Lamivudine Impurity I (Troxacitabine) 4-amino-1-[(2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl]-1,2-dihydropyrimidin-2-one (-)-Occc 2(1H)-Pyrimidinone, 4-amino-1-((2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl)- 2(1H)-Pyrimidinone, 4-amino-1-(-2-(hydroxymethyl)-1,3-dioxolan-4-yl)-, (2S-cis)- Bch 4556 L-Oddc Troxatyl Troxacitabine (SGX-145) SPD 758 α-L-Dioxolane-C Lamivudine Impurity I 4-amino-1-((2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl)pyrimidin-2(1H)-one Lamivudine EP Impurity I Lamivudine EP Impurity I (Troxacitabine) Troxacitabine(BCH4556) 4-amino-1-((2RS,4RS)-2-(hydroxymethyl)-1,3-dioxolan-4-yl)pyrimidin-2(1H)-one 4-amino-1-(2-(hydroxymethyl)-1,3-dioxolan-4-yl)pyrimidin-2(1H)-one 145918-75-8