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TROXACITABINE

TROXACITABINE Structure
TROXACITABINE structure
CAS No.
145918-75-8
Chemical Name:
TROXACITABINE
Synonyms
CS-150;L-Oddc;SPD 758;Bch 4556;(-)-Occc;Troxatyl;(-)-Bch 204;TROXACITABINE;α-L-Dioxolane-C;Lamivudine Impurity I
CBNumber:
CB71011675
Molecular Formula:
C8H11N3O4
Molecular Weight:
213.19
MDL Number:
MFCD00871100
MOL File:
145918-75-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:17
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TROXACITABINE Properties

Melting point 176-177°
alpha D25 -38.33° (c = 0.43 in MeOH).
Boiling point 422.5±55.0 °C(Predicted)
Density 1.71±0.1 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 14.83±0.10(Predicted)
color White to Off-White
Stability Hygroscopic
InChI InChI=1S/C8H11N3O4/c9-5-1-2-11(8(13)10-5)6-4-14-7(3-12)15-6/h1-2,6-7,12H,3-4H2,(H2,9,10,13)/t6-,7-/m0/s1
InChIKey RXRGZNYSEHTMHC-BQBZGAKWSA-N
SMILES C1(=O)N([C@@H]2CO[C@H](CO)O2)C=CC(N)=N1
EWG's Food Scores 1
NCI Dictionary of Cancer Terms troxacitabine
FDA UNII 60KQZ0388Y
NCI Drug Dictionary troxacitabine

TROXACITABINE price More Price(38)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 296507 Troxacitabine Asreported 145918-75-8 10mg $3787 2026-06-03 Buy
Usbiological 296507 Troxacitabine Asreported 145918-75-8 25mg $5097 2026-06-03 Buy
Usbiological 296507 Troxacitabine Asreported 145918-75-8 50mg $7397 2026-06-03 Buy
Usbiological 296507 Troxacitabine Asreported 145918-75-8 100mg $8742 2026-06-03 Buy
TRC TRC-T805580-5MG Troxacitabine 145918-75-8 5mg $3588 2026-06-03 Buy
Product number Packaging Price Buy
296507 10mg $3787 Buy
296507 25mg $5097 Buy
296507 50mg $7397 Buy
296507 100mg $8742 Buy
TRC-T805580-5MG 5mg $3588 Buy

TROXACITABINE Chemical Properties, Uses, Production

Uses

Troxacitabine is a nucleoside analogue with potential anticancer activity. Troxacitabine have been studied in patients with refractory lymphoproliferative diseases.

Definition

ChEBI: Troxacitabine is a nucleobase-containing molecular entity and a carbohydrate derivative.

in vivo

Troxacitabine is highly active against the Panc-01 model, with TGI levels of 88.5% and 84.3% at the 10 and 25 mg/kg doses, respectively. The mean final tumor weights for animals given troxacitabine are also significantly smaller compared with vehicle controls. Troxacitabine has less activity against the MiaPaCa model[3]. Troxacitabine is very effective in human RCC tumor xenograft models, including CAM-i, A498, RXF-393, and SN12C carcinomas. Very good responses are ob served in animals bearing CAM-i, A498, and RXF-393 RCC tumors given i.p. doses of 10, 25, and 50 mg/kg twice a day for 5 days[2].

TROXACITABINE Preparation Products And Raw materials

Raw materials

Preparation Products

TROXACITABINE Suppliers

Global Suppliers ( 95)
Supplier Tel Email Country ProdList Advantage
Hangzhou FuRun Pharmaceutical Technology Co., Ltd 15658004993 1900830611@qq.com China 980 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Shanghai Sphchem Co., Ltd. 021-56491756 13512199871 2819742715@qq.com China 3994 55
S.Z. PhyStandard Bio-Tech. Co., Ltd. 0755-4000505016 13380397412 3001272453@qq.com China 5000 50
Beijing HuaMeiHuLiBiological Chemical 010-56205725 waley188@sohu.com China 12323 58
AdooQ BioScience, LLC +1 (866) 930-6790 info@adooq.com United States 2774 58
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Quality Control Solutions Ltd. 0755-66853366 13670046396 orders@qcsrm.com China 18188 56
Shandong Boluoda Biological Technology Co., Ltd. 0531-68651502 2310993908@qq.com China 3228 58
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656 greensnown@163.com China 9883 50
Supplier Advantage
Hangzhou FuRun Pharmaceutical Technology Co., Ltd 58
J & K SCIENTIFIC LTD. 76
Shanghai Sphchem Co., Ltd. 55
S.Z. PhyStandard Bio-Tech. Co., Ltd. 50
Beijing HuaMeiHuLiBiological Chemical 58
AdooQ BioScience, LLC 58
Bide Pharmatech Ltd. 60
Quality Control Solutions Ltd. 56
Shandong Boluoda Biological Technology Co., Ltd. 58
Shanghai Kewel Chemical Co., Ltd. 50

View Latest Price from TROXACITABINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-amino-1-((2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl)pyrimidin-2(1H)-one pictures 2021-09-18 4-amino-1-((2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl)pyrimidin-2(1H)-one
145918-75-8
 10mg 99% 10KG Hangzhou Huarong Pharm Co., Ltd.
TROXACITABINE pictures 2020-01-05 TROXACITABINE
145918-75-8
 $1.00 1KG 95--99% 1ton Career Henan Chemical Co

TROXACITABINE Spectrum

TROXACITABINE(145918-75-8)1HNMR

145918-75-8 (TROXACITABINE) Related Search:

4-amino-1-((2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one Cytosine lamivudine sulfoxide Salicylic acid Lamivudine
Aids004768 Lamivudine EP Impurity A 4-(Hydroxymethyl)benzonitrile Gemcitabine lignocaine N-oxide
(2R,5R)-5-Hydroxy-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester Lamivudine Impurity 9 Lamivudine impurity 6 (1r,2s,5r)-2-Isopropyl-5-Methylcyclohexyl-5-Hydroxy-1,3oxathiolane-2-Carboxylate Antazoline
Uracil ent-LaMivudine Lamivudine EP Impurity B

1of4

TROXACITABINE TROXACITABINE,2(1H)-PYRIMIDINONE, 4-AMINO-1-(2-(HYDROXYMETHYL)-1,3-DIOXOLAN-4-YL)-, (2S-CIS)- 4-Amino-1-[(2S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl]pyrimidin-2-one (-)-Bch 204 CS-150 Lamivudine Impurity I (Troxacitabine) 4-amino-1-[(2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl]-1,2-dihydropyrimidin-2-one (-)-Occc 2(1H)-Pyrimidinone, 4-amino-1-((2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl)- 2(1H)-Pyrimidinone, 4-amino-1-(-2-(hydroxymethyl)-1,3-dioxolan-4-yl)-, (2S-cis)- Bch 4556 L-Oddc Troxatyl Troxacitabine (SGX-145) SPD 758 α-L-Dioxolane-C Lamivudine Impurity I 4-amino-1-((2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl)pyrimidin-2(1H)-one Lamivudine EP Impurity I Lamivudine EP Impurity I (Troxacitabine) Troxacitabine(BCH4556) 4-amino-1-((2RS,4RS)-2-(hydroxymethyl)-1,3-dioxolan-4-yl)pyrimidin-2(1H)-one 4-amino-1-(2-(hydroxymethyl)-1,3-dioxolan-4-yl)pyrimidin-2(1H)-one 145918-75-8