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ChemicalBook >> CAS DataBase List >>2-Pyridinecarbonitrile, 5-[[4-[(3-amino-3-methylbutyl)amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-

2-Pyridinecarbonitrile, 5-[[4-[(3-amino-3-methylbutyl)amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-

2-Pyridinecarbonitrile, 5-[[4-[(3-amino-3-methylbutyl)amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]- Structure
2-Pyridinecarbonitrile, 5-[[4-[(3-amino-3-methylbutyl)amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]- structure
CAS No.
2428423-77-0
Chemical Name:
2-Pyridinecarbonitrile, 5-[[4-[(3-amino-3-methylbutyl)amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-
Synonyms
Chk1-IN-6;2-Pyridinecarbonitrile, 5-[[4-[(3-amino-3-methylbutyl)amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-
CBNumber:
CB710872032
Molecular Formula:
C16H18F3N7
Molecular Weight:
365.36
MDL Number:
MOL File:
2428423-77-0.mol
MSDS File:
SDS
Last updated:2025-04-18 09:52:34
Request For Quotation

2-Pyridinecarbonitrile, 5-[[4-[(3-amino-3-methylbutyl)amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]- Properties

Boiling point 569.9±60.0 °C(Predicted)
Density 1.35±0.1 g/cm3(Predicted)
pka 10.01±0.25(Predicted)
form Solid
color White to off-white

2-Pyridinecarbonitrile, 5-[[4-[(3-amino-3-methylbutyl)amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0256258 Chk1-IN-6 98.39% 2428423-77-0 5mg $412 2026-06-04 Buy
ChemScene CS-0256258 Chk1-IN-6 98.39% 2428423-77-0 10mg $655 2026-06-04 Buy
ChemScene CS-0256258 Chk1-IN-6 98.39% 2428423-77-0 25mg $1311 2026-06-04 Buy
ChemScene CS-0256258 Chk1-IN-6 98.39% 2428423-77-0 50mg $2102 2026-06-04 Buy
ChemScene CS-0256258 Chk1-IN-6 98.39% 2428423-77-0 100mg $3358 2026-06-04 Buy
Product number Packaging Price Buy
CS-0256258 5mg $412 Buy
CS-0256258 10mg $655 Buy
CS-0256258 25mg $1311 Buy
CS-0256258 50mg $2102 Buy
CS-0256258 100mg $3358 Buy

2-Pyridinecarbonitrile, 5-[[4-[(3-amino-3-methylbutyl)amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]- Chemical Properties, Uses, Production

Uses

Chk1-IN-6 is a potent, selective, and orally bioavailable CHK1 inhibitor candidate.

IC 50

Chk1

References

[1] Jin T, et al. Discovery and Development of a Potent, Selective, and Orally Bioavailable CHK1 Inhibitor Candidate: 5-((4-((3-Amino-3-methylbutyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)picolinonitrile. J Med Chem. 2021 Oct 28;64(20):15069-15090. DOI:10.1021/acs.jmedchem.1c00994

2-Pyridinecarbonitrile, 5-[[4-[(3-amino-3-methylbutyl)amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]- Preparation Products And Raw materials

Raw materials

Preparation Products

2-Pyridinecarbonitrile, 5-[[4-[(3-amino-3-methylbutyl)amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]- Suppliers

Global Suppliers ( 4)
Supplier Tel Email Country ProdList Advantage
Shanghai SuperLan Chemcial Technique Centre 0-2022843681 15618226720 chaolaichem@foxmail.com China 9996 58
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
ShangHai Caerulum Pharma Discovery Co., Ltd. 15000803246 18149758185 sales-cpd@caerulumpharma.com China 474 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Supplier Advantage
Shanghai SuperLan Chemcial Technique Centre 58
BOC Sciences 58
ShangHai Caerulum Pharma Discovery Co., Ltd. 58
TargetMol Chemicals Inc. 58

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2-Pyridinecarbonitrile, 5-[[4-[(3-amino-3-methylbutyl)amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]- Chk1-IN-6 2428423-77-0 C16H18F3N7