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((S)-piperidin-3-yl)methanol

CAS No.
144539-77-5
Chemical Name:
((S)-piperidin-3-yl)methanol
Synonyms
3(S)-Piperidinemethanol;(3S)-3-PiperidineMethanol;(S)-Piperidine-3-methanol;3-Piperidinemethanol, (3S)-;(3S)-piperidin-3-ylMethanol;((S)-piperidin-3-yl)methanol;(S)-3-Hydroxymethyl-piperidine, 99.8%ee, 98%
CBNumber:
CB71094069
Molecular Formula:
C6H13NO
Molecular Weight:
115.17
MDL Number:
MFCD10567175
MOL File:
144539-77-5.mol
MSDS File:
SDS
Last updated:2026-05-28 02:26:32

((S)-piperidin-3-yl)methanol Properties

Boiling point 240.4±0.0 °C(Predicted)
Density 0.951
refractive index 1.451
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka 14.93±0.10(Predicted)
Appearance Colorless to light yellow Solid-liquid mixture

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338

((S)-piperidin-3-yl)methanol price More Price(46)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AK Scientific W3153 (S)-(Piperidin-3-yl)methanol 95%(HPLC) 144539-77-5 250mg $21 2026-06-04 Buy
AK Scientific W3153 (S)-(Piperidin-3-yl)methanol 95%(HPLC) 144539-77-5 1g $82 2026-06-04 Buy
AK Scientific W3153 (S)-(Piperidin-3-yl)methanol 95%(HPLC) 144539-77-5 5g $336 2026-06-04 Buy
AK Scientific W3153 (S)-(Piperidin-3-yl)methanol 95%(HPLC) 144539-77-5 10g $600 2026-06-04 Buy
AK Scientific W3153 (S)-(Piperidin-3-yl)methanol 95%(HPLC) 144539-77-5 25g $1234 2026-06-04 Buy
Product number Packaging Price Buy
W3153 250mg $21 Buy
W3153 1g $82 Buy
W3153 5g $336 Buy
W3153 10g $600 Buy
W3153 25g $1234 Buy

((S)-piperidin-3-yl)methanol Chemical Properties, Uses, Production

Uses

((S)-piperidin-3-yl)methanol is used to study enzymic chemoselective and enantioselective acyl transfers in hydroxymethylpiperidines.

Uses

(S)-3-Piperidinemethanol is used to study enzymic chemoselective and enantioselective acyl transfers in hydroxymethylpiperidines.

Synthesis

Ethyl (3S)-piperidine-3-carboxylate

37675-18-6

3-Piperidinemethanol

4606-65-9

General procedure for the synthesis of 3-hydroxymethylpiperidine from ethyl (S)-3-piperidinecarboxylate: lithium aluminum hydride (LAH, 118 mL, 1.0 M in ether, 1.0 equiv.) was slowly added to a solution of tetrahydrofuran (THF, 250 mL) of the product of step A (18.5 g, 0.125 mmol) over a period of 20 min at 0 °C. The reaction mixture was gradually warmed to room temperature and subsequently heated to reflux for 2 hours. Upon completion of the reaction, it was cooled to room temperature and the reaction was quenched by slow addition of saturated sodium sulfate (Na2SO4) solution. The resulting slurry was dried by the addition of anhydrous sodium sulfate (Na2SO4), filtered through diatomaceous earth and concentrated to give a colorless oily product (13.7 g, 98% crude yield). The product was detected by chemical ionization mass spectrometry (CIMS) showing a molecular ion peak (MH+) of 116; the specific optical rotation ([α]20D) was -8.4° (determined by dissolving 5.0 mg of the sample in 2 mL of methanol).

References

[1] Patent: US2003/229099, 2003, A1. Location in patent: Page 174
[2] Patent: US2004/122018, 2004, A1. Location in patent: Page 208
[3] Patent: EP1140904, 2005, B1. Location in patent: Page/Page column 33
[4] Patent: EP1553074, 2005, A1. Location in patent: Page/Page column 37
[5] Patent: WO2014/173855, 2014, A1. Location in patent: Page/Page column 17

((S)-piperidin-3-yl)methanol Preparation Products And Raw materials

Global Suppliers ( 82)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
ForeChem (Nantong) Technology Co.,Ltd. 513-85982855 18921614129 sales@xianxingpharm.com China 2712 61
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15350 60
Daicel Chiral Technologies (China)CO.,LTD 021-50460086-9 15921403865 han_yajun@dctc.daicel.com China 7917 65
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8663 57
Nanjing Vital Chemical Co., Ltd. Please Send Email 18652950785 chemweiao@163.com China 4368 65
Shanghai Topbiochem Technology Co., Ltd +86-21-60341587 sales@topbiochem.com China 6166 58
Shanghai T&W Pharmaceutical Co., Ltd. +86 21 61551611 China 9874 58
Shanghai Run-Biotech Co., Ltd. 021-57171705 13817537615 sales@run-biotech.com China 2277 58

View Latest Price from ((S)-piperidin-3-yl)methanol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(S)-(Piperidin-3-yl)methanol pictures 2022-01-27 (S)-(Piperidin-3-yl)methanol
144539-77-5
1KG 99.1% 100 tons Honest Joy Holdings Limited
((S)-piperidin-3-yl)methanol pictures 2019-12-26 ((S)-piperidin-3-yl)methanol
144539-77-5
$1.00 1KG 99% 1000KGS Career Henan Chemical Co

((S)-piperidin-3-yl)methanol Spectrum

((S)-piperidin-3-yl)methanol (3S)-piperidin-3-ylMethanol (3S)-3-PiperidineMethanol 3(S)-Piperidinemethanol (S)-3-Hydroxymethyl-piperidine, 99.8%ee, 98% (S)-Piperidine-3-methanol 3-Piperidinemethanol, (3S)- 144539-77-5 Chiral Reagents Heterocycles Intermediates