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4-(Chloromethyl)-1H-imidazole hydrochloride

4-(Chloromethyl)-1H-imidazole hydrochloride structure

CAS No.: 38585-61-4

Chemical Name:: 4-(Chloromethyl)-1H-imidazole hydrochloride

Synonyms: 5-(CHLOROMETHYL)-1H-IMIDAZOLE HCL;4-chloromethyl-imidazolhydrochloride;4-(Chloromethyl)imidazole Hydrochloride;4-Chloromethy-1H-imidazole Hydrochloride;4-Chloromethy-1(3)H-imidazole Hydrochlorid;5-(CHLOROMETHYL)-1H-IMIDAZOLE HYDROCHLORIDE;4-(Chloromethyl)-1H-imidazole hydrochloride;4-Chloromethyl-1(3)H-imidazole Hydrochloride;1H-IMidazole, 4-(chloroMethyl)-, Monohydrochloride;1H-Imidazole, 5-(chloromethyl)-, hydrochloride (1:1)

CBNumber:: CB7115086

Molecular Formula:: C4H6Cl2N2

Molecular Weight:: 153.01

MDL Number:: MFCD01721661

MOL File:: 38585-61-4.mol

MSDS File:: SDS

Last updated:2026-05-28 03:02:27

Product description	Number	Pack Size	Price
4-(Chloromethyl)-1H-imidazole hydrochloride AldrichCPR	CBR00821	1G	$506
4-Chloromethy-1H-imidazole Hydrochloride (4-Chloromethy-1(3)H-imidazole Hydrochloride)	C5024-36	100mg	$531
4-Chloromethyl-1H-imidazole Hydrochloride	TRC-C369190-50MG	50mg	$148
4-Chloromethyl-1H-imidazole Hydrochloride	TRC-C369190-250MG	250mg	$523
4-Chloromethyl-1H-imidazole Hydrochloride	TRC-C369190-100MG	100mg	$223

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4-(Chloromethyl)-1H-imidazole hydrochloride Properties

Melting point	1400C
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	Ethanol, Methanol, Tetrahydrofuran, Toluene
form	Solid
color	Beige
InChI	1S/C4H5ClN2.ClH/c5-1-4-2-6-3-7-4;/h2-3H,1H2,(H,6,7);1H
InChIKey	FASMXPUFMXBVRL-UHFFFAOYSA-N
SMILES	ClCC1=CNC=N1.[H]Cl
UNSPSC Code	12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS05,GHS07
Signal word	Danger
Hazard statements	H302-H315-H318-H335
Precautionary statements	P261-P280-P305+P351+P338
Hazard Codes	Xi
WGK Germany	WGK 3
HS Code	2933299090
Storage Class	11 - Combustible Solids
Hazard Classifications	Acute Tox. 4 Oral Eye Dam. 1 Skin Irrit. 2 STOT SE 3
Toxicity	mouse,LD50,intravenous,180mg/kg (180mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#05103,

4-(Chloromethyl)-1H-imidazole hydrochloride price More Price(61)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	CBR00821	4-(Chloromethyl)-1H-imidazole hydrochloride AldrichCPR	38585-61-4	1G	$506	2026-04-30	Buy
Usbiological	C5024-36	4-Chloromethy-1H-imidazole Hydrochloride (4-Chloromethy-1(3)H-imidazole Hydrochloride)	38585-61-4	100mg	$531	2026-06-03	Buy
TRC	TRC-C369190-50MG	4-Chloromethyl-1H-imidazole Hydrochloride	38585-61-4	50mg	$148	2026-06-03	Buy
TRC	TRC-C369190-250MG	4-Chloromethyl-1H-imidazole Hydrochloride	38585-61-4	250mg	$523	2026-06-03	Buy
TRC	TRC-C369190-100MG	4-Chloromethyl-1H-imidazole Hydrochloride	38585-61-4	100mg	$223	2026-06-03	Buy

Product number	Packaging	Price	Buy
CBR00821	1G	$506	Buy
C5024-36	100mg	$531	Buy
TRC-C369190-50MG	50mg	$148	Buy
TRC-C369190-250MG	250mg	$523	Buy
TRC-C369190-100MG	100mg	$223	Buy

4-(Chloromethyl)-1H-imidazole hydrochloride Chemical Properties,Uses,Production

Chemical Properties

Beige Solid

Uses

4-Chloromethyl-1H-imidazole Hydrochloride (cas# 38585-61-4) is a compound useful in organic synthesis.

Synthesis

32673-41-9

38585-61-4

(A) Synthesis of 4-(chloromethyl)-1H-imidazole hydrochloride (1) 2 mL of thionyl chloride was dissolved in 20 mL of toluene followed by the addition of 700 mg of 4-hydroxymethylimidazole hydrochloride. The reaction mixture was heated to the reflux temperature of toluene and maintained for 3 hours. Upon completion of the reaction, the mixture was cooled to room temperature and concentrated to dryness under reduced pressure. 4-(Chloromethyl)-1H-imidazole hydrochloride was finally obtained as a white solid (790 mg, 99% yield).

References

[1] Journal of Organic Chemistry, 1990, vol. 55, # 6, p. 1890 - 1901
[2] Patent: US5218115, 1993, A
[3] Journal of Organic Chemistry, 2008, vol. 73, # 21, p. 8591 - 8593
[4] Patent: US4847383, 1989, A
[5] Annales pharmaceutiques francaises, 1998, vol. 56, # 6, p. 250 - 255

4-(Chloromethyl)-1H-imidazole hydrochloride synthesis

Synthesis of 4-(Chloromethyl)-1H-imidazole hydrochloride from 4-Imidazolemethanol hydrochloride

4-(Chloromethyl)-1H-imidazole hydrochloride Preparation Products And Raw materials

Raw materials

4-Imidazolemethanol hydrochloride Toluene Thionyl chloride

Preparation Products

Imidazole-4-methanol

4-(Chloromethyl)-1H-imidazole hydrochloride Suppliers

Global( 90)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	+86-15225627621 +86-13213167925	jiuyitime@fdachem.com	China	16511	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
CONIER CHEM AND PHARMA LIMITED		sales@conier.com	China	49979	58
Career Henan Chemica Co	+86-0371-86658258 +86-13203830695	laboratory@coreychem.com	China	30224	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +86-189 4982 3763	sales@tnjchem.com	China	34563	58
Suzhou Victorypharm Co.,Ltd.	+86-13916956214	sales@victory-pharm.com	China	1299	58
Suzhou Laing Biotechnology Co.,Ltd	+86-13004516015 +86-18149392822	christina@laingbiotec.com	China	777	58
Aladdin Scientific		tp@aladdinsci.com	United States	52923	58
Hebei Chuanghai Biotechnology Co., Ltd	+86-15350571055	Sibel@chuanghaibio.com	China	6085	58
Wuhan Fortuna Chemical Co.,Ltd	+86-2759207851; +86-18007136271	hk@fortunachem.com	China	6006	58

Supplier	Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	58
ATK CHEMICAL COMPANY LIMITED	60
CONIER CHEM AND PHARMA LIMITED	58
Career Henan Chemica Co	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Suzhou Victorypharm Co.,Ltd.	58
Suzhou Laing Biotechnology Co.,Ltd	58
Aladdin Scientific	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Wuhan Fortuna Chemical Co.,Ltd	58

View Lastest Price from 4-(Chloromethyl)-1H-imidazole hydrochloride manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-07-02	4-(Chloromethyl)-1H-imidazole hydrochloride 38585-61-4	$1.10-9.90	1KG	99% min	100kg	ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

4-(Chloromethyl)-1H-imidazole hydrochloride
38585-61-4
$1.10-9.90
99% min
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

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5-(CHLOROMETHYL)-1H-IMIDAZOLE HYDROCHLORIDE 4-chloromethyl-imidazolhydrochloride 4-Chloromethy-1(3)H-imidazole Hydrochlorid 4-Chloromethy-1H-imidazole Hydrochloride 1H-Imidazole, 4-(chloromethyl)-, monohydrochloride (9CI) 4-(Chloromethyl)-1H-imidazole hydrochloride 1H-IMidazole, 4-(chloroMethyl)-, Monohydrochloride 1H-Imidazole, 5-(chloromethyl)-, hydrochloride (1:1) 4-Chloromethyl-1(3)H-imidazole Hydrochloride 5-(CHLOROMETHYL)-1H-IMIDAZOLE HCL 4-(Chloromethyl)imidazole Hydrochloride 38585-61-4 Heterocycles