Safrazine
- CAS No.
- 33419-68-0
- Chemical Name:
- Safrazine
- Synonyms
- Safrasine;Safrazine;Saphrazine;4-(1,3-benzodioxol-5-yl)butan-2-ylhydrazine;1-[3-(1,3-Benzodioxol-5-yl)-1-methylpropyl]hydrazine
- CBNumber:
- CB71179698
- Molecular Formula:
- C11H16N2O2
- Molecular Weight:
- 208.25694
- MDL Number:
- MOL File:
- 33419-68-0.mol
- MSDS File:
- SDS
| Boiling point | 347.46°C (rough estimate) |
|---|---|
| Density | 1.1123 (rough estimate) |
| refractive index | 1.5000 (estimate) |
| FDA UNII | F5G0P5378C |
Safrazine price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| aablocks | AA00CJ4C | [4-(1,3-dioxaindan-5-yl)butan-2-yl]hydrazine 95% | 33419-68-0 | 250mg | $922 | 2026-05-28 | Buy |
| aablocks | AA00CJ4C | [4-(1,3-dioxaindan-5-yl)butan-2-yl]hydrazine 95% | 33419-68-0 | 1g | $993 | 2026-05-28 | Buy |
| aablocks | AA00CJ4C | [4-(1,3-dioxaindan-5-yl)butan-2-yl]hydrazine 95% | 33419-68-0 | 5g | $2685 | 2026-05-28 | Buy |
| American Custom Chemicals Corporation | API0012453 | SAFRAZINE 95.00% | 33419-68-0 | 5MG | $505.34 | 2021-12-16 | Buy |
Safrazine Chemical Properties, Uses, Production
Uses
Safrazine is an irreversible, non-specific and orally active monoamine oxidase (MAO) inhibitor. Safrazine can be used for the research of depression[1].
in vivo
Safrazine (oral; 3, 10, 30 mg/kg) causes the increases contents of monoamine lasted for at least 24 h[1].
Safrazine strongly inhibits both 5-HT and PEA deaminations, but shows no selectivity toward the substrate used[1].
| Animal Model: | Male ddY mice[1] |
| Dosage: | 3, 10, 30 mg/kg |
| Administration: | Oral |
| Result: | Inhibited significantly both 5-HT and PEA deaminations at only 3 mg/kg by 77% and 71%, respectively. Completely reduced both deaminations at 10 and 30 mg/kg and not observed specificity toward substrates. |
References
[1] T Yokoyama, et al. Comparative studies of the effects of RS-8359 and safrazine on monoamine oxidase in-vitro and in-vivo in mouse brain. J Pharm Pharmacol. 1989 Jan;41(1):32-6. DOI:10.1111/j.2042-7158.1989.tb06324.x
Safrazine Preparation Products And Raw materials
Raw materials
Preparation Products
Safrazine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| TargetMol Chemicals Inc. | 13564774135 | marketing@targetmol.com | United States | 19950 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
