INDOMETHACIN SODIUM
- CAS No.
- 7681-54-1
- Chemical Name:
- INDOMETHACIN SODIUM
- Synonyms
- osmosin;sodiumindomethacin;IndoMetacine sodiuM;INDOMETHACIN SODIUM;IndoMethacin sodiuM salt;Sodium 2-(1-(4-chlorobenzoyl);sodium 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-ac...;sodium1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1h-indole-3-acetate;sodium:2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetate;1-(p-chlorobenzoyl)-5-methoxy-2-methyl-indole-3-aceticacisodiumsalt
- CBNumber:
- CB7121243
- Molecular Formula:
- C19H15ClNNaO4
- Molecular Weight:
- 379.77
- MDL Number:
- MFCD01939655
- MOL File:
- 7681-54-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| storage temp. | Sealed in dry,Room Temperature |
|---|---|
| form | Powder |
| InChI | InChI=1S/C19H16ClNO4.Na/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12;/h3-9H,10H2,1-2H3,(H,22,23);/q;+1/p-1 |
| InChIKey | JMHRGKDWGWORNU-UHFFFAOYSA-M |
| SMILES | C12C=CC(OC)=CC=1C(=C(C)N2C(=O)C1C=CC(Cl)=CC=1)CC([O-])=O.[Na+] |
| EWG's Food Scores | 1 |
| FDA UNII | 1C9D998830 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H300 |
| Precautionary statements | P264-P270-P301+P310-P321-P330-P405-P501 |
INDOMETHACIN SODIUM price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 452371 | Indomethacin sodium | 7681-54-1 | 1g | $1083 | 2026-06-03 | Buy |
| aablocks | AA00G42Q | sodium 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetate 98% | 7681-54-1 | 1g | $1300 | 2026-05-28 | Buy |
| Crysdot | CD11059946 | Sodium 2-(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetate 95+% | 7681-54-1 | 1g | $772 | 2026-05-26 | Buy |
| TRC | I641035 | Indomethacinsodium | 7681-54-1 | 5g | $2925 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | ING0002860 | INDOMETHACIN SODIUM 95.00% | 7681-54-1 | 1G | $945.95 | 2021-12-16 | Buy |
INDOMETHACIN SODIUM Chemical Properties, Uses, Production
Description
Indomethacin sodium is a potent, orally active COX1/2 inhibitor with IC50 values of 18 nM and 26 nM for COX-1 and COX-2, respectively. Indomethacin sodium has anticancer activity and anti-infective activity. Indomethacin sodium can be used for cancer, inflammation and viral infection research.
Uses
Anti-inflammatory.
brand name
Indocin (Ovation).
in vivo
Indomethacin (Indometacin) sodium (0.01-10 mg/kg; p.o.; for 3 hours; male Sprague-Dawley rats) induces paw oedema and hyperalgesmeasurement dose-dependently reversed carrageenan-induced hyperalgesia[1].
Indomethacin (Indometacin) sodium (10 mg/mL; p.o.; daily, for 29 days; male C57BL/6J mice) inhibits tumor growth in vivo[2].
| Animal Model: | Male Sprague-Dawley rats[1] |
| Dosage: | 0.01-10 mg/kg |
| Administration: | Oral administration; for 3 hours |
| Result: | Inhibited the carrageenan-induced rat paw oedema (ED50=2.0mg/kg) and hyperalgesia (ED50=1.5mg/kg) in a dose-dependent manner. |
| Animal Model: | Male C57BL/6J mice[2] |
| Dosage: | 10 mg/mL |
| Administration: | Oral administration; daily, for 29 days |
| Result: | Delayed the onset of tumor growth and the initial growth rate of the footpad tumors. |
IC 50
COX-1: IC50 = 0.1 μM (sheep); Cox-1: IC50 = 1.67 μM (human);
COX-2: IC50 = 6 μM (sheep); Cox-2: IC50 = 24.6 μM (human)
INDOMETHACIN SODIUM Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Fortuna Chemical Co., Ltd | 027-59207852 13308628970 | buy@fortunachem.com | China | 2690 | 58 |
| Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 | info@sagechem.com | China | 10265 | 58 |
| Hubei XinyuanShun Chemical Co., Ltd. | 13971561712, 13995564702, 027-50664929 | hbeixys2001@163.com | China | 3110 | 55 |
| Hangzhou J&H Chemical Co., Ltd. | 0571-87396432 | sales@jhechem.com | China | 14905 | 59 |
| Hubei Jusheng Technology Co.,Ltd | 027-59599241 18871490274 | 1400878000@qq.com | China | 9506 | 58 |
| Shanghai QianYan Bio-technology Co., Ltd | 02781293128 | orders@biochemsafebuy.com | China | 9904 | 55 |
| Wuhan Magic Biological Technology Co., Ltd. | 18872289958、027-52304252、3400508168 | 3400508168@qq.com | China | 1901 | 55 |
| Guangzhou Kafen Biotech Co.,Ltd | 18029243487 2355327168 | gy@yccreate.com | China | 4738 | 55 |
| Wuhai Shuou Technology Co., Ltd. | 17792809151;18872220797 | 2355916837@ycphar.com | China | 6120 | 55 |
| Taian Jiaye Biotechnology Co.Ltd | 15318151873;13127280945 | 285424065@qq.com | China | 9961 | 55 |
View Latest Price from INDOMETHACIN SODIUM manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-16 | Indometacine sodium
7681-54-1
|
1KG | 98.0% | 5tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-07-27 | Indomethacin sodium
7681-54-1
|
$1520.00-2500.00 | 10g | TargetMol Chemicals Inc. | |||
 |
2026-03-27 | sodium 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate
7681-54-1
|
25KG | 50-70% HPLC | 5000kgs | shandong perfect biotechnology co.ltd |
-
- Indometacine sodium
7681-54-1
- $0.00
- 98.0%
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Indomethacin sodium
7681-54-1
- $1520.00-2500.00
- TargetMol Chemicals Inc.
-
- sodium 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate
7681-54-1
- $0.00
- 50-70% HPLC
- shandong perfect biotechnology co.ltd
