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Tripelennamine hydrochloride

CAS No.
154-69-8
Chemical Name:
Tripelennamine hydrochloride
Synonyms
Azaron;Tripyridamole hydrochloride;TRIPELENNAMINE HCL;ReCovr;dehistin;piristin;Ahistamin;pyrinamine;stanzamine;tri-tumine
CBNumber:
CB7126697
Molecular Formula:
C16H22ClN3
Molecular Weight:
291.82
MDL Number:
MFCD00012815
MOL File:
154-69-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:54:27

Tripelennamine hydrochloride Properties

Melting point 192-193℃
Density 1.20
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility DMSO : 25 mg/mL (85.67 mM; Need ultrasonic)
form Solid
color White to off-white
Major Application cleaning products
cosmetics
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)
veterinary
InChI InChI=1S/C16H21N3.ClH/c1-18(2)12-13-19(16-10-6-7-11-17-16)14-15-8-4-3-5-9-15;/h3-11H,12-14H2,1-2H3;1H
InChIKey FSSICIQKZGUEAE-UHFFFAOYSA-N
SMILES N(CCN(C)C)(CC1=CC=CC=C1)C1=NC=CC=C1.Cl
FDA UNII FWV8GJ56ZN
EPA Substance Registry System Tripelennamine hydrochloride (154-69-8)
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P301+P312-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Codes  Xn
Risk Statements  22-36/37/38
Safety Statements  26-36
WGK Germany  3
RTECS  US3150000
HS Code  2933399090
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Toxicity LD50 in mice (mg/kg): 47 i.p. (Walker)

Tripelennamine hydrochloride price More Price(55)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich R288918 TRIPELENNAMINE HYDROCHLORIDE AldrichCPR 154-69-8 1 unit $197 2026-04-30 Buy
Sigma-Aldrich PHR3258 Tripelennamine Hydrochloride certified reference material, pharmaceutical secondary standard 154-69-8 500MG $201 2026-04-30 Buy
Sigma-Aldrich 1695004 TRIPELENNAMINE HYDROCHLORIDE United States Pharmacopeia (USP) Reference Standard 154-69-8 200mg $382 2026-04-30 Buy
Sigma-Aldrich R288918 TRIPELENNAMINE HYDROCHLORIDE Aldrich 154-69-8 1g $179 2024-03-01 Buy
Cayman Chemical 44223 Tripelennamine (hydrochloride) ≥98% 154-69-8 500mg $83 2026-04-30 Buy
Product number Packaging Price Buy
R288918 1 unit $197 Buy
PHR3258 500MG $201 Buy
1695004 200mg $382 Buy
R288918 1g $179 Buy
44223 500mg $83 Buy

Tripelennamine hydrochloride Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

Tripelennamine is a first-generation antihistamine, used in the treatment of asthma, hay fever, and urticaria.

Uses

antihistaminic;histamine H1 antagonist

brand name

PBZ (Novartis).

General Description

Tripelennamine hydrochlorideis a white crystalline powder that darkensslowly on exposure to light. The salt is soluble in water(1:0.77) and in alcohol (1:6). It has a pKa of about 9, and a0.1% solution has a pH of about 5.5.
Tripelennamine, the first ethylenediamine developed inthe United States and is well absorbed when given orally. Itappears to be as effective as diphenhydramine and may havethe advantage of fewer and less severe side reactions.Drowsiness may occur, however, and may impair the abilityto perform tasks requiring alertness. The concurrent use ofalcoholic beverages should be avoided.

General Description

Odorless white crystalline powder or solid. Bitter taste. Solutions are neutral to litmus. pH of aqueous solution (25 mg/mL): 6.71. pH of aqueous solution (50 mg/mL): 6.67. pH of aqueous solution (100 mg/mL): 5.56.

Air & Water Reactions

Water soluble.

Reactivity Profile

TRIPELENNAMINE HYDROCHLORIDE behaves as a weak organic acid. Materials in this group are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible.

Fire Hazard

Flash point data for TRIPELENNAMINE HYDROCHLORIDE are not available; however, TRIPELENNAMINE HYDROCHLORIDE is probably combustible.

Veterinary Drugs and Treatments

Antihistamines are used in veterinary medicine to reduce or help prevent histamine mediated adverse effects. Tripelennamine has been used as a CNS stimulant in “Downer cows” when administered slow IV.

Tripelennamine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 203)Suppliers
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Sinopharm Chemical Reagent Co,Ltd. 86-21-63210123 sj_scrc@sinopharm.com China 9791 79
Spectrum Chemical Manufacturing Corp. 021-021-021-67601398-809-809-809 15221380277 marketing_china@spectrumchemical.com China 9643 60
Haoyuan Chemexpress Co., Ltd. 021-58950125 info@chemexpress.com China 7545 61
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 13167063860 anhua.mao@aladdin-e.com China 29985 65
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4853 58
Hubei Datong Bio-Chemical Technology Co.,Ltd 027-87666700 xuri@hbdatongchem.com China 145 55
TargetMol Chemicals Inc. 021-021-33632979 15002134094 marketing@targetmol.com China 7993 58

View Lastest Price from Tripelennamine hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
TripelennaMine Hydrochloride pictures 2026-09-11 TripelennaMine Hydrochloride
154-69-8
100g 98%-102%;USP 1000G WUHAN FORTUNA CHEMICAL CO., LTD
TripelennaMine Hydrochloride pictures 2026-02-02 TripelennaMine Hydrochloride
154-69-8
$1.00 1g 99% 50tons Shaanxi Dideu Medichem Co. Ltd
Tripelennamine (hydrochloride) pictures 2023-02-13 Tripelennamine (hydrochloride)
154-69-8
$10.00 1kg 99% 50MT Hebei baicao biology science and technology co., ltd

Tripelennamine hydrochloride Spectrum

2-(benzyl(2-(dimethylamino)ethyl)amino)-pyridinmonohydrochloride 2-ethanediamine,n,n-dimethyl-n’-(phenylmethyl)-n’-2-pyridinyl-monohydroc 2-(benzyl(2-(dimethylamino)ethyl)amino)pyridinemonohydrochloride 2-(benzyl(2-(dimethylamino)ethyl)amino)-pyridinhydrochloride 1,2-Ethanediamine, N,N-dimethyl-N'-(phenylmethyl)-N'-2-pyridinyl-, monohydrochloride Ahistamin Antiallergicum medivet Ethylenediamine, N-benzyl-N',N'-dimethyl-N-(2-pyridyl)-, hydrochloride N(Sup 1)-.alpha.-pyridyl-N(sup 1)-benzyl-N,N-dimethyl ethylenediamine monohydrochloride N1,N1-Dimethyl-N2-(phenylmethyl)-N2-(2-pyridinyl)-1,2-ethanediamine hydrochloride ReCovr Tripelennamine Hydrochloride (200 mg) N-Benzyl-N',N'-diMethyl-N-2-pyridylethylen TRIPELENNAMINE HYDROCHLORIDE TABLETS TripelennaMine HCI N-benzyl-N-(2-(dimethylamino)ethyl)pyridin-2-amine hydrochloride N1-Benzyl-N2,N2-dimethyl-N1-(pyridin-2-yl)ethane-1,2-diamine hydrochloride dehistin dehistinmonohydrochloride n(sup1)-alpha-pyridyl-n(sup1)-benzyl-n,n-dimethylethylenediaminemonohydro n,n-dimethyl-n’-(2-pyridyl)-n’-benzylethylenediaminehydrochloride n-benzyl-n’,n’-dimethyl-n-(2-pyridyl)-ethylenediaminhydrochloride n-benzyl-n’,n’-dimethyl-n-2-pyridyl-ethylenediaminehydrochloride n-benzyl-n-alpha-pyridyl-n’,n’-dimethyl-aethylendiamin-hydrochlorid n-benzyl-n-dimethylaminoethylalpha-aminopyridinehydrochloride piristin pyrabenzamine pyribenzaminehydrochloride pyribenzaminemonohydrochloride pyrinamine stanzamine tripelenaminehydrochloride tripelennaminemonohydrochloride tri-tumine PYRIBENZAMINE HCL 2-(benzyl[2-dimethylaminoethyl]amino)pyridine TRIPELENNAMINEHYDROCHLORIDE,USP PYRIDINE,2-(BENZYL(2-(DIMETHYLAMINO)ETHYL)AMINO)-,MONOHYDROCHLORIDE TRIPELENAMINEHCL 2-(Benzyl[2-dimethylaminoethyl]amino)pyridine, N-Benzyl-Nμ,Nμ-dimethyl-N-(2-pyridyl)ethylenediamine hydrochloride Tripelennanmine Hydrochloride 2-[BENZYL(2-DIMETHYLAMINOETHYL)AMINO]PYRIDINE HYDROCHLORIDE N-Benzyl-N',N'-dimethyl-N-pyridin-2-yl-ethane-1,2-diamine HYDROCHLORIDE TRIPELENNAMINE HCL N,N-dimethyl-N'-(phenylmethyl)-N'-(2-pyridinyl)ethane-1,2-diamine hydrochloride 1,2-Ethanediamine,N1,N1-dimethyl-N2-(phenylmethyl)-N2-2-pyridinyl-, hydrochloride (1:1) Tripelennamine Hydrochloride Standard Chloropyramine Impurity 1 HCl (Tripelennamine HCl, Pyribenzamine HCl) Chloropyramine Impurity 1 HCl TRIPELENNAMINE HYDROCHLORIDE USP/EP/BP TIANFU 154-69-8 TRIPELENNAMINE HYDROCHLORIDE Tripelennamine,Inhibitor,inhibit,antihistaminic,Tripelennamine hydrochloride,Histamine Receptor,rhinitis,allergic response,conjunctivitis,Endogenous Metabolite BMS-986165 (Deucravacitinib) second-generation Avanafil Impurity 103 Tripelennamine hydrochloride in methanol Tripelennamine hydrochloride, 10 mM in DMSO Zoledronic acid monohydrate - Bio-X ? Tripelennamine hydrochloride 100 μg/mL in Acetonitrile