Tripelennamine hydrochloride
- CAS No.
- 154-69-8
- Chemical Name:
- Tripelennamine hydrochloride
- Synonyms
- Azaron;Tripyridamole hydrochloride;TRIPELENNAMINE HCL;ReCovr;dehistin;piristin;Ahistamin;pyrinamine;stanzamine;tri-tumine
- CBNumber:
- CB7126697
- Molecular Formula:
- C16H22ClN3
- Molecular Weight:
- 291.82
- MDL Number:
- MFCD00012815
- MOL File:
- 154-69-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 192-193℃ |
|---|---|
| Density | 1.20 |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMSO : 25 mg/mL (85.67 mM; Need ultrasonic) |
| form | Solid |
| color | White to off-white |
| Major Application |
cleaning products cosmetics food and beverages forensics and toxicology personal care pharmaceutical (small molecule) veterinary |
| InChI | InChI=1S/C16H21N3.ClH/c1-18(2)12-13-19(16-10-6-7-11-17-16)14-15-8-4-3-5-9-15;/h3-11H,12-14H2,1-2H3;1H |
| InChIKey | FSSICIQKZGUEAE-UHFFFAOYSA-N |
| SMILES | N(CCN(C)C)(CC1=CC=CC=C1)C1=NC=CC=C1.Cl |
| FDA UNII | FWV8GJ56ZN |
| EPA Substance Registry System | Tripelennamine hydrochloride (154-69-8) |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P264-P270-P301+P312-P302+P352-P305+P351+P338 |
| target organs | Respiratory system |
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
| Hazard Codes | Xn |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| RTECS | US3150000 |
| HS Code | 2933399090 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
| Toxicity | LD50 in mice (mg/kg): 47 i.p. (Walker) |
Tripelennamine hydrochloride price More Price(55)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | R288918 | TRIPELENNAMINE HYDROCHLORIDE AldrichCPR | 154-69-8 | 1 unit | $197 | 2026-04-30 | Buy |
| Sigma-Aldrich | PHR3258 | Tripelennamine Hydrochloride certified reference material, pharmaceutical secondary standard | 154-69-8 | 500MG | $201 | 2026-04-30 | Buy |
| Sigma-Aldrich | 1695004 | TRIPELENNAMINE HYDROCHLORIDE United States Pharmacopeia (USP) Reference Standard | 154-69-8 | 200mg | $382 | 2026-04-30 | Buy |
| Sigma-Aldrich | R288918 | TRIPELENNAMINE HYDROCHLORIDE Aldrich | 154-69-8 | 1g | $179 | 2024-03-01 | Buy |
| Cayman Chemical | 44223 | Tripelennamine (hydrochloride) ≥98% | 154-69-8 | 500mg | $83 | 2026-04-30 | Buy |
Tripelennamine hydrochloride Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
Tripelennamine is a first-generation antihistamine, used in the treatment of asthma, hay fever, and urticaria.
Uses
antihistaminic;histamine H1 antagonist
brand name
PBZ (Novartis).
General Description
Tripelennamine hydrochlorideis a white crystalline powder that darkensslowly on exposure to light. The salt is soluble in water(1:0.77) and in alcohol (1:6). It has a pKa of about 9, and a0.1% solution has a pH of about 5.5.
Tripelennamine, the first ethylenediamine developed inthe United States and is well absorbed when given orally. Itappears to be as effective as diphenhydramine and may havethe advantage of fewer and less severe side reactions.Drowsiness may occur, however, and may impair the abilityto perform tasks requiring alertness. The concurrent use ofalcoholic beverages should be avoided.
General Description
Odorless white crystalline powder or solid. Bitter taste. Solutions are neutral to litmus. pH of aqueous solution (25 mg/mL): 6.71. pH of aqueous solution (50 mg/mL): 6.67. pH of aqueous solution (100 mg/mL): 5.56.
Air & Water Reactions
Water soluble.
Reactivity Profile
TRIPELENNAMINE HYDROCHLORIDE behaves as a weak organic acid. Materials in this group are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible.
Fire Hazard
Flash point data for TRIPELENNAMINE HYDROCHLORIDE are not available; however, TRIPELENNAMINE HYDROCHLORIDE is probably combustible.
Veterinary Drugs and Treatments
Antihistamines are used in veterinary medicine to reduce or help prevent histamine mediated adverse effects. Tripelennamine has been used as a CNS stimulant in “Downer cows” when administered slow IV.
Tripelennamine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky(shanghai)International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Sinopharm Chemical Reagent Co,Ltd. | 86-21-63210123 | sj_scrc@sinopharm.com | China | 9791 | 79 |
| Spectrum Chemical Manufacturing Corp. | 021-021-021-67601398-809-809-809 15221380277 | marketing_china@spectrumchemical.com | China | 9643 | 60 |
| Haoyuan Chemexpress Co., Ltd. | 021-58950125 | info@chemexpress.com | China | 7545 | 61 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29985 | 65 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4853 | 58 |
| Hubei Datong Bio-Chemical Technology Co.,Ltd | 027-87666700 | xuri@hbdatongchem.com | China | 145 | 55 |
| TargetMol Chemicals Inc. | 021-021-33632979 15002134094 | marketing@targetmol.com | China | 7993 | 58 |
View Lastest Price from Tripelennamine hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-09-11 | TripelennaMine Hydrochloride
154-69-8
|
100g | 98%-102%;USP | 1000G | WUHAN FORTUNA CHEMICAL CO., LTD | ||
![]() |
2026-02-02 | TripelennaMine Hydrochloride
154-69-8
|
$1.00 | 1g | 99% | 50tons | Shaanxi Dideu Medichem Co. Ltd | |
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2023-02-13 | Tripelennamine (hydrochloride)
154-69-8
|
$10.00 | 1kg | 99% | 50MT | Hebei baicao biology science and technology co., ltd |
-

- TripelennaMine Hydrochloride
154-69-8
- $0.00
- 98%-102%;USP
- WUHAN FORTUNA CHEMICAL CO., LTD
-

- TripelennaMine Hydrochloride
154-69-8
- $1.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-

- Tripelennamine (hydrochloride)
154-69-8
- $10.00
- 99%
- Hebei baicao biology science and technology co., ltd
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