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ChemicalBook >> CAS DataBase List >>2-Propenamide, N-[3-[[(2R)-2-(acetylamino)-1-oxo-3-(phenylmethoxy)propyl]amino]propyl]-2-cyano-3-(4-hydroxyphenyl)-, (2E)-

2-Propenamide, N-[3-[[(2R)-2-(acetylamino)-1-oxo-3-(phenylmethoxy)propyl]amino]propyl]-2-cyano-3-(4-hydroxyphenyl)-, (2E)-

2-Propenamide, N-[3-[[(2R)-2-(acetylamino)-1-oxo-3-(phenylmethoxy)propyl]amino]propyl]-2-cyano-3-(4-hydroxyphenyl)-, (2E)- Structure
2-Propenamide, N-[3-[[(2R)-2-(acetylamino)-1-oxo-3-(phenylmethoxy)propyl]amino]propyl]-2-cyano-3-(4-hydroxyphenyl)-, (2E)- structure
CAS No.
1687735-82-5
Chemical Name:
2-Propenamide, N-[3-[[(2R)-2-(acetylamino)-1-oxo-3-(phenylmethoxy)propyl]amino]propyl]-2-cyano-3-(4-hydroxyphenyl)-, (2E)-
Synonyms
Aldose reductase-IN-2;2-Propenamide, N-[3-[[(2R)-2-(acetylamino)-1-oxo-3-(phenylmethoxy)propyl]amino]propyl]-2-cyano-3-(4-hydroxyphenyl)-, (2E)-
CBNumber:
CB712687340
Molecular Formula:
C25H28N4O5
Molecular Weight:
464.51
MDL Number:
MOL File:
1687735-82-5.mol
MSDS File:
SDS
Last updated:2026-04-21 10:31:43
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2-Propenamide, N-[3-[[(2R)-2-(acetylamino)-1-oxo-3-(phenylmethoxy)propyl]amino]propyl]-2-cyano-3-(4-hydroxyphenyl)-, (2E)- Properties

Boiling point 841.1±65.0 °C(Predicted)
Density 1.247±0.06 g/cm3(Predicted)
pka 9.20±0.26(Predicted)

2-Propenamide, N-[3-[[(2R)-2-(acetylamino)-1-oxo-3-(phenylmethoxy)propyl]amino]propyl]-2-cyano-3-(4-hydroxyphenyl)-, (2E)- Chemical Properties, Uses, Production

Uses

Aldose reductase-IN-2 (Compound 5f) is a potent inhibitor of aldose reductase (AR). Aldose reductase-IN-2 has antioxidation capacity. Aldose reductase-IN-2 is a promising anti-diabetic complications agent[1].

References

[1] Liu Y, et al. Enhanced antioxidation capacity endowed to a mixed type aldose reductase inhibitor leads to a promising anti-diabetic complications agent [published online ahead of print, 2022 Jan 17]. Bioorg Chem. 2022;120:105624. DOI:10.1016/j.bioorg.2022.105624

2-Propenamide, N-[3-[[(2R)-2-(acetylamino)-1-oxo-3-(phenylmethoxy)propyl]amino]propyl]-2-cyano-3-(4-hydroxyphenyl)-, (2E)- Preparation Products And Raw materials

Raw materials

Preparation Products

2-Propenamide, N-[3-[[(2R)-2-(acetylamino)-1-oxo-3-(phenylmethoxy)propyl]amino]propyl]-2-cyano-3-(4-hydroxyphenyl)-, (2E)- Suppliers

Global Suppliers ( 2)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58
Supplier Advantage
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58

View Latest Price from 2-Propenamide, N-[3-[[(2R)-2-(acetylamino)-1-oxo-3-(phenylmethoxy)propyl]amino]propyl]-2-cyano-3-(4-hydroxyphenyl)-, (2E)- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Aldose reductase-IN-2 pictures 2026-04-20 Aldose reductase-IN-2
1687735-82-5
 $2140.00-3520.00 10g TargetMol Chemicals Inc.

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2-Propenamide, N-[3-[[(2R)-2-(acetylamino)-1-oxo-3-(phenylmethoxy)propyl]amino]propyl]-2-cyano-3-(4-hydroxyphenyl)-, (2E)- Aldose reductase-IN-2 1687735-82-5