| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Aldose reductase-IN-2
CAS:1687735-82-5
Package:1removed
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2-Propenamide, N-[3-[[(2R)-2-(acetylamino)-1-oxo-3-(phenylmethoxy)propyl]amino]propyl]-2-cyano-3-(4-hydroxyphenyl)-, (2E)- manufacturers
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| | 2-Propenamide, N-[3-[[(2R)-2-(acetylamino)-1-oxo-3-(phenylmethoxy)propyl]amino]propyl]-2-cyano-3-(4-hydroxyphenyl)-, (2E)- Basic information |
| | 2-Propenamide, N-[3-[[(2R)-2-(acetylamino)-1-oxo-3-(phenylmethoxy)propyl]amino]propyl]-2-cyano-3-(4-hydroxyphenyl)-, (2E)- Chemical Properties |
| Boiling point | 841.1±65.0 °C(Predicted) | | density | 1.247±0.06 g/cm3(Predicted) | | pka | 9.20±0.26(Predicted) |
| | 2-Propenamide, N-[3-[[(2R)-2-(acetylamino)-1-oxo-3-(phenylmethoxy)propyl]amino]propyl]-2-cyano-3-(4-hydroxyphenyl)-, (2E)- Usage And Synthesis |
| Uses | Aldose reductase-IN-2 (Compound 5f) is a potent inhibitor of aldose reductase (AR). Aldose reductase-IN-2 has antioxidation capacity. Aldose reductase-IN-2 is a promising anti-diabetic complications agent[1]. | | References | [1] Liu Y, et al. Enhanced antioxidation capacity endowed to a mixed type aldose reductase inhibitor leads to a promising anti-diabetic complications agent [published online ahead of print, 2022 Jan 17]. Bioorg Chem. 2022;120:105624. DOI:10.1016/j.bioorg.2022.105624 |
| | 2-Propenamide, N-[3-[[(2R)-2-(acetylamino)-1-oxo-3-(phenylmethoxy)propyl]amino]propyl]-2-cyano-3-(4-hydroxyphenyl)-, (2E)- Preparation Products And Raw materials |
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