3-Methoxy-2-methylaniline
- CAS No.
- 19500-02-8
- Chemical Name:
- 3-Methoxy-2-methylaniline
- Synonyms
- 3-Methoxy-2-nitroaniline;3-Metho;3-methoxy-2-methylbenzenamine;2-Nitro-m-anisidine;2-Methyl-M-anisidine;3-METHOXY-O-TOLUIDINE;3-Methoxy-2-methylanili;2-METHYL-3-AMINO ANISOLE;3-AMINO-2-METHYL-ANISOLE;2-AMino-6-Methoxytoluene
- CBNumber:
- CB4278801
- Molecular Formula:
- C8H11NO
- Molecular Weight:
- 137.18
- MDL Number:
- MFCD06412568
- MOL File:
- 19500-02-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 27-28°C |
|---|---|
| Boiling point | 243.4±20.0 °C(Predicted) |
| Density | 1.08 |
| refractive index | 1.5730-1.5770 |
| Flash point | >110℃ |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Oil |
| pka | 4.03±0.10(Predicted) |
| color | Brown to Dark Brown |
| InChI | InChI=1S/C8H11NO/c1-6-7(9)4-3-5-8(6)10-2/h3-5H,9H2,1-2H3 |
| InChIKey | OPXLVWLFDKRYRB-UHFFFAOYSA-N |
| SMILES | C1(N)=CC=CC(OC)=C1C |
| CAS DataBase Reference | 19500-02-8(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS06,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H301+H311+H331-H315-H319-H302 | |||||||||
| Precautionary statements | P261-P264-P270-P271-P280-P301+P310+P330-P302+P352+P312+P361+P364-P304+P340+P311-P305+P351+P338+P337+P313-P403+P233-P405-P501 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| RIDADR | 2810 | |||||||||
| WGK Germany | 1 | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 2921490090 | |||||||||
| NFPA 704 |
|
3-Methoxy-2-methylaniline price More Price(50)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | M1493 | 3-Methoxy-2-methylaniline >98.0%(GC)(T) | 19500-02-8 | 5g | $84 | 2026-04-30 | Buy |
| TCI Chemical | M1493 | 3-Methoxy-2-methylaniline >98.0%(GC)(T) | 19500-02-8 | 25g | $330 | 2025-07-31 | Buy |
| TRC | TRC-M263300-1G | 3-Methoxy-2-methylaniline | 19500-02-8 | 1g | $85 | 2026-06-03 | Buy |
| AstaTech | 26101 | 3-METHOXY-2-METHYLANILINE 97% | 19500-02-8 | 5G | $37 | 2026-04-30 | Buy |
| AstaTech | 26101 | 3-METHOXY-2-METHYLANILINE 97% | 19500-02-8 | 10G | $70 | 2026-04-30 | Buy |
3-Methoxy-2-methylaniline Chemical Properties, Uses, Production
Chemical Properties
Brown Oil
Uses
3-Methoxy-2-methylaniline is a aniline derivative used in the preparation of indoles and indazoles with potential neurochemical activity, as well as in the preparation of quinoline based antiviral agents.
Synthesis
4837-88-1
19500-02-8
The general procedure for the synthesis of 3-methoxy-2-methylaniline from 2-methyl-3-nitroanisole is as follows (reference Example 42): 1. 9.98 g of a suspension of 5% palladium-carbon (wet) in 100 mL of ethanol was added to a solution of 30.7 g (184 mmol) of 2-methyl-3-nitroanisole in 300 mL of ethanol. 2. The reaction mixture was stirred at room temperature and under hydrogen atmosphere for 3 hours. 3. Upon completion of the reaction, the reaction solution was filtered through diatomaceous earth. 4. The filtrate was concentrated under vacuum to give 25.5 g of 3-methoxy-2-methylaniline as a light purple oil (Yield: quantitative). Rf value: 0.38 (hexane: ethyl acetate = 2:1, v/v). Mass spectrum (EI, m/z): 137 (M+). 1H-NMR spectrum (CDCl3, δ ppm): 2.04-2.05 (m, 3H), 3.60 (brs, 2H), 3.80 (s, 3H), 6.33-6.37 (m, 2H), 6.94-7.01 (m, 1H).
References
[1] Patent: EP1679308, 2006, A1. Location in patent: Page/Page column 56
[2] Patent: US2009/12123, 2009, A1. Location in patent: Page/Page column 14-15
[3] Patent: WO2004/103996, 2004, A1. Location in patent: Page 38-39
[4] Patent: WO2006/7700, 2006, A1. Location in patent: Page/Page column 61
[5] Patent: US2006/19905, 2006, A1. Location in patent: Page/Page column 24
3-Methoxy-2-methylaniline Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Tetranov Biopharm | 13526569071 | sales@leadmedpharm.com | China | 7881 | 64 |
| Shanghai Longsheng chemical Co.,Ltd. | 58099637 13585536065 | sales@shlschem.com | China | 9880 | 59 |
| Shanghai Harvest Chemical Industrial Co., Ltd. | 15721252604 17321035817 | sales@harvest-chem.com | China | 2829 | 64 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
View Latest Price from 3-Methoxy-2-methylaniline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-25 | 3-Methoxy-2-methylaniline
19500-02-8
|
$3.00-9.00 | 99% | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |||
 |
2026-03-20 | 3-Methoxy-2-methylaniline
19500-02-8
|
1KG | 99% | 20 mt | Hebei Chuanghai Biotechnology Co., Ltd | ||
 |
2024-04-23 | 3-Methoxy-2-methylaniline
19500-02-8
|
$30.00-100.00 | 1kg | 99.93% | 1000kg per week | Ouhuang Engineering Materials (Hubei) Co., Ltd |
-
- 3-Methoxy-2-methylaniline
19500-02-8
- $3.00-9.00
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- 3-Methoxy-2-methylaniline
19500-02-8
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 3-Methoxy-2-methylaniline
19500-02-8
- $30.00-100.00
- 99.93%
- Ouhuang Engineering Materials (Hubei) Co., Ltd
19500-02-8 (3-Methoxy-2-methylaniline) Related Search:
1of4
