Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>1H-Isoindole-1,3(2H)-dione, 4-[[1-cyclopropyl-5-(2-methyl-4-pyridinyl)-1H-benzimidazol-6-yl]amino]-2-(2,6-dioxo-3-piperidinyl)-

1H-Isoindole-1,3(2H)-dione, 4-[[1-cyclopropyl-5-(2-methyl-4-pyridinyl)-1H-benzimidazol-6-yl]amino]-2-(2,6-dioxo-3-piperidinyl)-

1H-Isoindole-1,3(2H)-dione, 4-[[1-cyclopropyl-5-(2-methyl-4-pyridinyl)-1H-benzimidazol-6-yl]amino]-2-(2,6-dioxo-3-piperidinyl)- Structure
1H-Isoindole-1,3(2H)-dione, 4-[[1-cyclopropyl-5-(2-methyl-4-pyridinyl)-1H-benzimidazol-6-yl]amino]-2-(2,6-dioxo-3-piperidinyl)- structure
CAS No.
3036553-83-7
Chemical Name:
1H-Isoindole-1,3(2H)-dione, 4-[[1-cyclopropyl-5-(2-methyl-4-pyridinyl)-1H-benzimidazol-6-yl]amino]-2-(2,6-dioxo-3-piperidinyl)-
Synonyms
WIZ degrader 7;1H-Isoindole-1,3(2H)-dione, 4-[[1-cyclopropyl-5-(2-methyl-4-pyridinyl)-1H-benzimidazol-6-yl]amino]-2-(2,6-dioxo-3-piperidinyl)-
CBNumber:
CB714686136
Molecular Formula:
C29H24N6O4
Molecular Weight:
520.54
MDL Number:
MOL File:
3036553-83-7.mol
Last updated:2025-04-17 18:22:24
Request For Quotation

1H-Isoindole-1,3(2H)-dione, 4-[[1-cyclopropyl-5-(2-methyl-4-pyridinyl)-1H-benzimidazol-6-yl]amino]-2-(2,6-dioxo-3-piperidinyl)- Properties

Density 1.58±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka 10.72±0.40(predicted)

1H-Isoindole-1,3(2H)-dione, 4-[[1-cyclopropyl-5-(2-methyl-4-pyridinyl)-1H-benzimidazol-6-yl]amino]-2-(2,6-dioxo-3-piperidinyl)- Chemical Properties,Uses,Production

Uses

WIZ degrader 7 (Example 16) is a WIZ degrader with an IC50 value of < 0.01 μM. WIZ degrader 7 can be used to investigate sickle cell disease (SCD) and thalassemia[1].

References

[1] Thomas J, et al. Compounds and their use for treatment of hemoglobinopathies. WO2024097932A1.2024-05-10.

1H-Isoindole-1,3(2H)-dione, 4-[[1-cyclopropyl-5-(2-methyl-4-pyridinyl)-1H-benzimidazol-6-yl]amino]-2-(2,6-dioxo-3-piperidinyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

1H-Isoindole-1,3(2H)-dione, 4-[[1-cyclopropyl-5-(2-methyl-4-pyridinyl)-1H-benzimidazol-6-yl]amino]-2-(2,6-dioxo-3-piperidinyl)- Suppliers

Global( 2)Suppliers
Supplier Tel Email Country ProdList Advantage
Alfa Chemistry +1-5166625404; Info@alfa-chemistry.com United States 20000 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Supplier Advantage
Alfa Chemistry 58
TargetMol Chemicals Inc. 58

3036553-83-7(1H-Isoindole-1,3(2H)-dione, 4-[[1-cyclopropyl-5-(2-methyl-4-pyridinyl)-1H-benzimidazol-6-yl]amino]-2-(2,6-dioxo-3-piperidinyl)-)Related Search:

6-pentadecylsalicylic acid 1H-Isoindole-1,3(2H)-dione, 5-[4-[[trans-4-[5-acetyl-3-[7-(difluoromethyl)-3,4-dihydro-6-(1-methyl-1H-pyrazol-4-yl)-1(2H)-quinolinyl]-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-1-yl]cyclohexyl]methyl]-1-piperazinyl]-2-(2,6-dioxo-3-piperidinyl)- MOZ-IN-3 GNE-781 PU139
WM-3835

1of2

1H-Isoindole-1,3(2H)-dione, 4-[[1-cyclopropyl-5-(2-methyl-4-pyridinyl)-1H-benzimidazol-6-yl]amino]-2-(2,6-dioxo-3-piperidinyl)- WIZ degrader 7 3036553-83-7