5-BROMO-2-METHYL-2H-INDAZOLE
- CAS No.
- 465529-56-0
- Chemical Name:
- 5-BROMO-2-METHYL-2H-INDAZOLE
- Synonyms
- 5-BROMO-2-METHYLINDAZOLE;2-Methyl-5-bromoindazole;2-methyl-5-bromo -2H-indazo;5-BROMO-2-METHYL-2H-INDAZOLE;2-Methyl-5-bromo-2H-indazole;2H-INDAZOLE, 5-BROMO-2-METHYL-
- CBNumber:
- CB71494111
- Molecular Formula:
- C8H7BrN2
- Molecular Weight:
- 211.06
- MDL Number:
- MFCD09870047
- MOL File:
- 465529-56-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 5-Bromo-2-methylindazole Asreported | 266279 | 250mg | $350 |
| 5-Bromo-2-methylindazole Asreported | 266279 | 500mg | $482 |
| 5-Bromo-2-methylindazole Asreported | 266279 | 1g | $811 |
| 5-Bromo-2-methylindazole Asreported | 266279 | 2g | $1134 |
| 5-Bromo-2-methylindazole Asreported | 266279 | 5g | $1609 |
| More product size | |||
| Boiling point | 322.7±15.0 °C(Predicted) |
|---|---|
| Density | 1.60±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | -0.06±0.30(Predicted) |
| Appearance | Light yellow to brown Solid |
| InChI | InChI=1S/C8H7BrN2/c1-11-5-6-4-7(9)2-3-8(6)10-11/h2-5H,1H3 |
| InChIKey | QFZOHVHNTZTZMJ-UHFFFAOYSA-N |
| SMILES | N1=C2C(C=C(Br)C=C2)=CN1C |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| HS Code | 2933998090 |
5-BROMO-2-METHYL-2H-INDAZOLE price More Price(66)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 266279 | 5-Bromo-2-methylindazole Asreported | 465529-56-0 | 250mg | $350 | 2026-06-03 | Buy |
| Usbiological | 266279 | 5-Bromo-2-methylindazole Asreported | 465529-56-0 | 500mg | $482 | 2026-06-03 | Buy |
| Usbiological | 266279 | 5-Bromo-2-methylindazole Asreported | 465529-56-0 | 1g | $811 | 2026-06-03 | Buy |
| Usbiological | 266279 | 5-Bromo-2-methylindazole Asreported | 465529-56-0 | 2g | $1134 | 2026-06-03 | Buy |
| Usbiological | 266279 | 5-Bromo-2-methylindazole Asreported | 465529-56-0 | 5g | $1609 | 2026-06-03 | Buy |
5-BROMO-2-METHYL-2H-INDAZOLE Chemical Properties,Uses,Production
Synthesis
53857-57-1
74-88-4
465529-56-0
465529-57-1
To a solution of 5-bromo-1H-indazole (0.19 g, 0.94 mmol) in THF (3 mL), NaH (0.04 g, 1.03 mmol) was slowly added at 0 °C. The reaction mixture was stirred at this temperature for 1 h, followed by the addition of iodomethane (0.09 mL, 1.41 mmol) at 0 °C. The reaction mixture was allowed to warm slowly to room temperature and stirring was continued for 2 hours. Upon completion of the reaction, the reaction was quenched with water and concentrated under reduced pressure. The residue was diluted with water and extracted twice with dichloromethane (DCM). The organic layers were combined, dried over anhydrous sodium sulfate (Na2SO4), filtered and concentrated. Purification of the crude product by fast column chromatography (eluent: hexane/ethyl acetate = 10:1) afforded 5-bromo-1-methyl-1H-indazole (ii) (88.7 mg, 42.5%) and 5-bromo-2-methyl-2H-indazole (iii) (60.9 mg, 29%), both as white solids. The 1H-NMR (400 MHz, DMSO-d6) δ ppm of compound ii: 8.02 (d, 1H), 7.99 (d, 1H), 7.64 (d, 1H), 7.50 (dd, 1H), 4.04 (s, 3H). lcms (Method A): [MH]+ = 211/213, tR = 5.19 min. compound iii The 1H-NMR (400 MHz, DMSO-d6) δ ppm: 8.33 (s, 1H), 7.95 (d, 1H), 7.57 (d, 1H), 7.30 (dd, 1H), 4.16 (s, 3H). lCMS (Method A): [MH]+ = 211/213, tR = 4.95 min.
References
[1] Patent: CN105254613, 2016, A. Location in patent: Paragraph 0131; 0132; 0133; 0134; 0135
[2] Journal of Organic Chemistry, 2018, vol. 83, # 12, p. 6334 - 6353
[3] Patent: WO2011/18454, 2011, A1. Location in patent: Page/Page column 60-61
[4] Patent: WO2011/20861, 2011, A1. Location in patent: Page/Page column 59
[5] Chemische Berichte, 1922, vol. 55, p. 1141,1157
5-BROMO-2-METHYL-2H-INDAZOLE Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32998 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29766 | 58 |
| Biochempartner | 0086-13720134139 | candy@biochempartner.com | CHINA | 963 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21135 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +86-18530059196 | sale04@alfachem.cn | China | 9636 | 58 |
| Blocksynth Pharmaceutical Technology Co.,Ltd | 0086-19817745290; 19817745290 | bd@blocksynth.com | China | 5971 | 58 |
| Finetech Industry Limited | +86-27-8746-5837 +86-18627785180 | info@finetechnology-ind.com | China | 9539 | 58 |
View Lastest Price from 5-BROMO-2-METHYL-2H-INDAZOLE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2021-07-13 | 5-BROMO-2-METHYL-2H-INDAZOLE
465529-56-0
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2021-07-10 | 5-BROMO-2-METHYL-2H-INDAZOLE
465529-56-0
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2019-07-11 | 5-BROMO-2-METHYL-2H-INDAZOLE
465529-56-0
|
$3.00 | 1KG | 99 | 100kg | Career Henan Chemical Co |
-
- 5-BROMO-2-METHYL-2H-INDAZOLE
465529-56-0
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 5-BROMO-2-METHYL-2H-INDAZOLE
465529-56-0
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 5-BROMO-2-METHYL-2H-INDAZOLE
465529-56-0
- $3.00
- 99
- Career Henan Chemical Co
