ChemicalBook >> CAS DataBase List >>4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)acetanilide

4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)acetanilide

4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)acetanilide structure

CAS No.: 214360-60-8

Chemical Name:: 4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)acetanilide

Synonyms: 2-dioxaborolan-2-yl)acetanilide;4-ACETAMIDOPHENYLBORONIC ACID, PINACOL ESTER;4-acetylaminophenylboronic acid pinacol ester;4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-Y;4-(Acetamido)benzeneboronic acid, pinacol ester;4-ACETAMIDOPHENYLBORONIC ACID, PINACOL CYCLIC ESTER;4-ACETYLAMINOPHENYLBORONIC ACID PINACOL CYCLIC ESTER;4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)ACETANILIDE;4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)acetanilide;2-(4-ACETAMIDOPHENYL)-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE

CBNumber:: CB7154304

Molecular Formula:: C14H20BNO3

Molecular Weight:: 261.12

MDL Number:: MFCD02093722

MOL File:: 214360-60-8.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-09-12 18:54:40

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4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)acetanilide Properties

Melting point	160-164 °C(lit.)
Boiling point	423.2±28.0 °C(Predicted)
Density	1.07±0.1 g/cm3(Predicted)
storage temp.	Sealed in dry,2-8°C
Water Solubility	Insoluble in water
pka	15.26±0.70(Predicted)
form	Powder
color	white
InChI	1S/C14H20BNO3/c1-10(17)16-12-8-6-11(7-9-12)15-18-13(2,3)14(4,5)19-15/h6-9H,1-5H3,(H,16,17)
InChIKey	ANGKVUVZQVUVJO-UHFFFAOYSA-N
SMILES	CC(=O)Nc1ccc(cc1)B2OC(C)(C)C(C)(C)O2
CAS DataBase Reference	214360-60-8(CAS DataBase Reference)
UNSPSC Code	12352103
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

target organs

Respiratory system

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36

WGK Germany

TSCA

HS Code

29349990

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

NFPA 704

	0
2		0

4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)acetanilide price More Price(46)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	518778	4-Acetamidophenylboronic acid pinacol ester 97%	214360-60-8	1g	$52.8	2023-06-20	Buy
Sigma-Aldrich	518778	4-Acetamidophenylboronic acid pinacol ester 97%	214360-60-8	5g	$239	2023-01-07	Buy
TCI Chemical	T1950	4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)acetanilide >98.0%(GC)	214360-60-8	1g	$78	2026-04-30	Buy
Strem Chemicals	05-1032	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)acetanilide, min. 97% min.97%	214360-60-8	1g	$92	2026-04-30	Buy
Strem Chemicals	05-1032	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)acetanilide, min. 97% min.97%	214360-60-8	5g	$358	2026-04-30	Buy

Product number	Packaging	Price	Buy
518778	1g	$52.8	Buy
518778	5g	$239	Buy
T1950	1g	$78	Buy
05-1032	1g	$92	Buy
05-1032	5g	$358	Buy

4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)acetanilide Chemical Properties, Uses, Production

Chemical Properties

Light yellow to light beige powder

Synthesis

122-80-5

73183-34-3

4'-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)ACETANILIDE

214360-60-8

The general procedure for the synthesis of 4-acetylaminophenylboronic acid pinacol ester from 4-aminoacetanilide and bis(boronic acid) pinacol ester is as follows: Example 6: Synthesis of N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide In a 25 mL tubular reactor, N-(4-aminophenyl)acetamide (1 mmol, 150 mg), pinacol ester of bis(boronic acid) (B2pin2, 1.2 mmol, 305 mg), benzoyl peroxide (0.02 mmol, 5 mg), and acetonitrile (3 mL) were added sequentially. Subsequently, tert-butyl nitrite (1.5 mmol, 154 mg) was added. The reaction was carried out at room temperature with stirring for 1 hour. After completion of the reaction, the reaction solution was concentrated and purified by column chromatography (eluent: petroleum ether/ethyl acetate=20:1, V/V) to afford the target compound N-(4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide as a white solid in 93% yield. The nuclear magnetic resonance (NMR) data of the compound are as follows: 1H NMR (400 MHz, CDCl3) δ 7.76 (d, 1H, J = 8.4 Hz), 7.53 (d, 1H, J = 8.3 Hz), 2.16 (s, 3H), 1.33-1.24 (m, 12H). 13C NMR (100 MHz, CDCl3) δ 168.5, 140.5, 135.6, 128.8, 119.9, 118.5, 83.6, 74.9, 24.9, 24.7, 24.5, 24.4.

References

[1] Angewandte Chemie - International Edition, 2010, vol. 49, # 10, p. 1846 - 1849
[2] Patent: US2012/184768, 2012, A1. Location in patent: Page/Page column 3
[3] Patent: EP2481742, 2012, A1. Location in patent: Page/Page column 5

4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)acetanilide Preparation Products And Raw materials

Raw materials

4'-Bromoacetanilide 4'-Aminoacetanilide N-(4-Iodophenyl)acetamide Pinacolborane Bis(pinacolato)diboron

Benzoyl peroxide Acetonitrile tert-Butyl nitrite

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Preparation Products

4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)acetanilide Suppliers

Global Suppliers ( 129)

Supplier	Tel	Email	Country	ProdList	Advantage
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Wuhan Chemwish Technology Co., Ltd	86-027-67849912	sales@chemwish.com	China	35884	56
Capot Chemical Co., Ltd	+86 (0) 571 85 58 67 18		China	18187	66
Pure Chemistry Scientific Inc.	001-857-928-2050 or 1-888-588-9418	sales@chemreagents.com	United States	10174	62
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64
Maya High Purity Chemicals	+86 (573) 82222445 (0)18006601000 452520369	sales@maya-r.com	China	11693	57
Beijing Yisiyan Technology Research Center	010-56645598 13366904824;	bjkaida@163.com	China	1596	59

Supplier	Advantage
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
TCI (Shanghai) Development Co., Ltd.	81
Energy Chemical	61
Wuhan Chemwish Technology Co., Ltd	56
Capot Chemical Co., Ltd	66
Pure Chemistry Scientific Inc.	62
Shanghai Hanhong Scientific Co.,Ltd.	64
Maya High Purity Chemicals	57
Beijing Yisiyan Technology Research Center	59

View Latest Price from 4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)acetanilide manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-08-25	4'-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)ACETANILIDE 214360-60-8	$3.00-9.00		99%		ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

4'-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)ACETANILIDE
214360-60-8
$3.00-9.00
99%
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)acetanilide Spectrum

4'-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)ACETANILIDE(214360-60-8)¹HNMR 4'-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)ACETANILIDE(214360-60-8)IR

214360-60-8 (4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)acetanilide) Related Search:

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)acetanilide 2-Acetamidophenylboronic acid 3-Acetamidophenylboronic acid 4-Acetamidophenylboronic acid 2'-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)ACETANILIDE,2-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)ACETANILIDE

4-Acetoxyphenylboronic acid 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl acetate 7-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indolin-2-one 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl) indolin-2-one 4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)acetanilide

2,2,2-Trifluoro-N-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-acetamide N-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]succinamic acid N-(2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide Boron

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2-(4-ACETAMIDOPHENYL)-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE 4-ACETYLAMINOPHENYLBORONIC ACID PINACOL CYCLIC ESTER 4-ACETAMIDOPHENYLBORONIC ACID, PINACOL CYCLIC ESTER 4-ACETAMIDOPHENYLBORONIC ACID, PINACOL ESTER 4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)ACETANILIDE 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)acetanilide,min.97% 4-acetylaminophenylboronic acid pinacol ester 4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)ACETANILIDE, MIN. 97% 4-Acetamidophenylboronic acid, pinacol cyclic ester, 4μ-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)acetanilide 4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)acetanilide,97+% N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide 4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)acetanilide ,98% 2-dioxaborolan-2-yl)acetanilide 4-(Acetamido)benzeneboronic acid, pinacol ester 4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-Y 4-Acetamidophenylboronic acid pinacol ester 4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)acetanilide Acetamide, N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]- N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ace... 4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)acetanilide 214360-60-8 C14H20BNO3 Organometallic Reagents Aryl Boronic Acids and Derivatives Boronate Esters Boronic Acids Esters B (Classes of Boron Compounds) organic or inorganic borate Boronic acids B (Classes of Boron Compounds) Boronic Acids Esters