3-Bromo-5-iodo-pyridine
- CAS No.
- 233770-01-9
- Chemical Name:
- 3-Bromo-5-iodo-pyridine
- Synonyms
- Zinc00336771;5-BROMO-3-IODOPYRIDINE;3-BROMO-5-IODO-PYRIDINE;Pyridine, 3-bromo-5-iodo-;3-Bromo-5-iodopyridine >C5H3BrIN 3-BROMO-5-IODOPYRIDINE;3-
BroMo- 5- iodopyridine;3-Bromo-5-iodo-pyridine ISO 9001：2015 REACH
- CBNumber:
- CB3409686
- Molecular Formula:
- C5H3BrIN
- Molecular Weight:
- 283.89
- MDL Number:
- MFCD03086019
- MOL File:
- 233770-01-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 127-131 °C |
|---|---|
| Boiling point | 266.5±25.0 °C(Predicted) |
| Density | 2.347±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | 0.85±0.20(Predicted) |
| form | Solid |
| color | Off-white |
| Water Solubility | Slightly soluble in water. |
| Sensitive | Light Sensitive |
| InChI | InChI=1S/C5H3BrIN/c6-4-1-5(7)3-8-2-4/h1-3H |
| InChIKey | AOOZLVWDZUPEHT-UHFFFAOYSA-N |
| SMILES | C1=NC=C(I)C=C1Br |
| CAS DataBase Reference | 233770-01-9(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H318 | |||||||||
| Precautionary statements | P280-P301+P312+P330-P305+P351+P338+P310 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-41-22 | |||||||||
| Safety Statements | 26-36/37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Harmful | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2933399990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Dam. 1 |
|||||||||
| NFPA 704 |
|
3-Bromo-5-iodo-pyridine price More Price(82)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 691453 | 3-Bromo-5-iodopyridine 95% | 233770-01-9 | 1g | $67.3 | 2026-04-30 | Buy |
| Sigma-Aldrich | 691453 | 3-Bromo-5-iodopyridine 95% | 233770-01-9 | 250mg | $94.4 | 2022-05-15 | Buy |
| TCI Chemical | B4346 | 3-Bromo-5-iodopyridine >98.0%(GC) | 233770-01-9 | 1g | $99 | 2026-04-30 | Buy |
| TCI Chemical | B4346 | 3-Bromo-5-iodopyridine >98.0%(GC) | 233770-01-9 | 5g | $343 | 2026-04-30 | Buy |
| Usbiological | 264358 | 3-Bromo-5-iodopyridine Asreported | 233770-01-9 | 500mg | $410 | 2026-06-03 | Buy |
3-Bromo-5-iodo-pyridine Chemical Properties,Uses,Production
Chemical Properties
Off-white Cryst
Uses
Reactant in the synthesis chiral 4, 4-Bipyridines. 3-bromo-5-(trifluoromethyl)pyridine is prepared from 3-Bromo-5-iodopyridine.
Synthesis
625-92-3
233770-01-9
General procedure for the synthesis of 3-bromo-5-iodopyridine from 3,5-dibromopyridine: 3,5-dibromopyridine (0.52 g, 2.19 mmol) was dissolved in anhydrous tetrahydrofuran (4 mL) at -10 °C, keeping the internal temperature below -5 °C. Subsequently, tetrahydrofuran solution of 2M isopropylmagnesium chloride (0.25 g, 2.11 mmol) and anhydrous tetrahydrofuran solution of iodine (0.62 g, 2.11 mmol) were added sequentially and slowly and stirred for about 5 minutes. After completion of the reaction, the reaction mixture was diluted with ethyl acetate and saturated aqueous sodium bisulfite. The organic layer was separated, dried over magnesium sulfate, filtered and concentrated to afford 3-bromo-5-iodopyridine (4.85 g, 98% yield), which can be used directly for further purification. The product characterization data were as follows: 1H NMR (400 MHz, CDCl3) δ 7.54-7.51 (m, 1H), 8.26 (s, 1H), 8.42 (s, 1H); MS (ES): m/z = 284 [M + H]+.
References
[1] Patent: WO2005/94822, 2005, A1. Location in patent: Page/Page column 35
[2] Chemistry - A European Journal, 2010, vol. 16, # 41, p. 12425 - 12433
[3] European Journal of Organic Chemistry, 2002, # 2, p. 327 - 330
[4] Patent: US2006/4018, 2006, A1. Location in patent: Page/Page column 12; 27
[5] Recueil des Travaux Chimiques des Pays-Bas, 1955, vol. 74, p. 1062,1068
3-Bromo-5-iodo-pyridine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Weihai Huaixin Biotechnology Co., Ltd | 15662379806 | 845423637@qq.com | China | 2800 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | sales@boylechem.com | China | 2915 | 55 | |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Suzhou Chireach Biomedical Technology Co., Ltd. | 0512-65856968 | sales@chireach.com | China | 59 | 70 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shijiazhuang Sdyano Fine Chemical Co., Ltd. | 0311-89250318 13582355795 | master@sjzsdyn.com | China | 2776 | 65 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 |
View Lastest Price from 3-Bromo-5-iodo-pyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-11 | 3-Bromo-5-iodo-pyridine
233770-01-9
|
1kg | 98%min | 500KGS | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-08-20 | 3-Bromo-5-iodo-pyridine
233770-01-9
|
$1.10 | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited | |
 |
2022-01-27 | 3-Bromo-5-iodopyridine
233770-01-9
|
1KG | 97.5% | 100 tons | Honest Joy Holdings Limited |
-
- 3-Bromo-5-iodo-pyridine
233770-01-9
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 3-Bromo-5-iodo-pyridine
233770-01-9
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 3-Bromo-5-iodopyridine
233770-01-9
- $0.00
- 97.5%
- Honest Joy Holdings Limited
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