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3-Bromo-5-iodo-pyridine

CAS No.
233770-01-9
Chemical Name:
3-Bromo-5-iodo-pyridine
Synonyms
Zinc00336771;5-BROMO-3-IODOPYRIDINE;3-BROMO-5-IODO-PYRIDINE;Pyridine, 3-bromo-5-iodo-;3-Bromo-5-iodopyridine >C5H3BrIN 3-BROMO-5-IODOPYRIDINE;3-BroMo-5-iodopyridine;3-Bromo-5-iodo-pyridine ISO 9001:2015 REACH
CBNumber:
CB3409686
Molecular Formula:
C5H3BrIN
Molecular Weight:
283.89
MDL Number:
MFCD03086019
MOL File:
233770-01-9.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 06:27:40
Product description Number Pack Size Price
3-Bromo-5-iodopyridine 95% 691453 1g $67.3
3-Bromo-5-iodopyridine 95% 691453 250mg $94.4
3-Bromo-5-iodopyridine >98.0%(GC) B4346 1g $99
3-Bromo-5-iodopyridine >98.0%(GC) B4346 5g $343
3-Bromo-5-iodopyridine Asreported 264358 500mg $410
More product size

3-Bromo-5-iodo-pyridine Properties

Melting point 127-131 °C
Boiling point 266.5±25.0 °C(Predicted)
Density 2.347±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka 0.85±0.20(Predicted)
form Solid
color Off-white
Water Solubility Slightly soluble in water.
Sensitive Light Sensitive
InChI InChI=1S/C5H3BrIN/c6-4-1-5(7)3-8-2-4/h1-3H
InChIKey AOOZLVWDZUPEHT-UHFFFAOYSA-N
SMILES C1=NC=C(I)C=C1Br
CAS DataBase Reference 233770-01-9(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Exclamation Mark (GHS07)
GHS05,GHS07
Signal word  Danger
Hazard statements  H302-H318
Precautionary statements  P280-P301+P312+P330-P305+P351+P338+P310
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-41-22
Safety Statements  26-36/37/39
WGK Germany  3
Hazard Note  Harmful
HazardClass  IRRITANT
HS Code  2933399990
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Eye Dam. 1
NFPA 704
1
2 0

3-Bromo-5-iodo-pyridine price More Price(90)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 691453 3-Bromo-5-iodopyridine 95% 233770-01-9 1g $67.3 2026-04-30 Buy
Sigma-Aldrich 691453 3-Bromo-5-iodopyridine 95% 233770-01-9 250mg $94.4 2022-05-15 Buy
TCI Chemical B4346 3-Bromo-5-iodopyridine >98.0%(GC) 233770-01-9 1g $99 2026-04-30 Buy
TCI Chemical B4346 3-Bromo-5-iodopyridine >98.0%(GC) 233770-01-9 5g $343 2026-04-30 Buy
Usbiological 264358 3-Bromo-5-iodopyridine Asreported 233770-01-9 500mg $410 2026-06-03 Buy
Product number Packaging Price Buy
691453 1g $67.3 Buy
691453 250mg $94.4 Buy
B4346 1g $99 Buy
B4346 5g $343 Buy
264358 500mg $410 Buy

3-Bromo-5-iodo-pyridine Chemical Properties,Uses,Production

Chemical Properties

Off-white Cryst

Uses

Reactant in the synthesis chiral 4, 4-Bipyridines. 3-bromo-5-(trifluoromethyl)pyridine is prepared from 3-Bromo-5-iodopyridine.

Synthesis

3,5-Dibromopyridine

625-92-3

3-Bromo-5-iodo-pyridine

233770-01-9

General procedure for the synthesis of 3-bromo-5-iodopyridine from 3,5-dibromopyridine: 3,5-dibromopyridine (0.52 g, 2.19 mmol) was dissolved in anhydrous tetrahydrofuran (4 mL) at -10 °C, keeping the internal temperature below -5 °C. Subsequently, tetrahydrofuran solution of 2M isopropylmagnesium chloride (0.25 g, 2.11 mmol) and anhydrous tetrahydrofuran solution of iodine (0.62 g, 2.11 mmol) were added sequentially and slowly and stirred for about 5 minutes. After completion of the reaction, the reaction mixture was diluted with ethyl acetate and saturated aqueous sodium bisulfite. The organic layer was separated, dried over magnesium sulfate, filtered and concentrated to afford 3-bromo-5-iodopyridine (4.85 g, 98% yield), which can be used directly for further purification. The product characterization data were as follows: 1H NMR (400 MHz, CDCl3) δ 7.54-7.51 (m, 1H), 8.26 (s, 1H), 8.42 (s, 1H); MS (ES): m/z = 284 [M + H]+.

References

[1] Patent: WO2005/94822, 2005, A1. Location in patent: Page/Page column 35
[2] Chemistry - A European Journal, 2010, vol. 16, # 41, p. 12425 - 12433
[3] European Journal of Organic Chemistry, 2002, # 2, p. 327 - 330
[4] Patent: US2006/4018, 2006, A1. Location in patent: Page/Page column 12; 27
[5] Recueil des Travaux Chimiques des Pays-Bas, 1955, vol. 74, p. 1062,1068

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View Lastest Price from 3-Bromo-5-iodo-pyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-Bromo-5-iodo-pyridine pictures 2026-07-15 3-Bromo-5-iodo-pyridine
233770-01-9
1kg 98%min 500KGS WUHAN FORTUNA CHEMICAL CO., LTD
3-Bromo-5-iodo-pyridine pictures 2025-11-18 3-Bromo-5-iodo-pyridine
233770-01-9
$1.10 1g 99.00% 100 Tons min Dideu Industries Group Limited
3-Bromo-5-iodopyridine pictures 2022-01-27 3-Bromo-5-iodopyridine
233770-01-9
1KG 97.5% 100 tons Honest Joy Holdings Limited

3-Bromo-5-iodo-pyridine Spectrum

5-BROMO-3-IODOPYRIDINE 3-BROMO-5-IODO-PYRIDINE Zinc00336771 3-BroMo-5-iodopyridine C5H3BrIN 3-BROMO-5-IODOPYRIDINE 3-Bromo-5-iodopyridine > Pyridine, 3-bromo-5-iodo- 3-Bromo-5-iodo-pyridine ISO 9001:2015 REACH 233770-01-9 Pyridine Series C5Heterocyclic Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks Pyridines Pyridine Heterocycle