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Dimethyl Glutarate

CAS No.
1119-40-0
Chemical Name:
Dimethyl Glutarate
Synonyms
Pentanedioic acid, dimethyl ester;GLUTARIC ACID DIMETHYL ESTER;Methyl glutarate;DIMETHYL PENTANEDIOATE;Glutaric acid dimethyl;DBE-2;dbe-5;methylglutarate;Dimethylglutarat;DBE-5 DIBASIC ESTER
CBNumber:
CB7170973
Molecular Formula:
C7H12O4
Molecular Weight:
160.17
MDL Number:
MFCD00008468
MOL File:
1119-40-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-06-24 18:39:39
Product description Number Pack Size Price
Dimethyl glutarate for synthesis 8.14659 250ML $51.4
Dimethyl glutarate for synthesis 8.14659 1L $128
DBE-5 dibasic ester 99% D158801 100g $70.3
Dimethyl Glutarate >98.0%(GC) G0185 25g $25
Dimethyl Glutarate >98.0%(GC) G0185 100g $50
More product size

Dimethyl Glutarate Properties

Melting point −13 °C(lit.)
Boiling point 96-103 °C15 mm Hg(lit.)
Density 1.09 g/mL at 25 °C(lit.)
vapor pressure 0.2 mm Hg ( 20 °C)
refractive index n20/D 1.424(lit.)
Flash point 218 °F
storage temp. Store below +30°C.
solubility 4.3g/l
form Liquid
color Clear colorless
Odor estery floral
explosive limit 0.9-7.9%(V)
Viscosity 2.53mm2/s
Water Solubility 53 g/L
FreezingPoint -42.5℃
Merck 14,4473
BRN 1771444
Henry's Law Constant 1.5×101 mol/(m3Pa) at 25℃, Duchowicz et al. (2020)
Stability Stable. Combustible. Incompatible with acids, bases, reducing agents, oxidizing agents.
Cosmetics Ingredients Functions SKIN CONDITIONING - EMOLLIENT
SOLVENT
ANTISTATIC
Cosmetic Ingredient Review (CIR) Dimethyl Glutarate (1119-40-0)
InChI 1S/C7H12O4/c1-10-6(8)4-3-5-7(9)11-2/h3-5H2,1-2H3
InChIKey XTDYIOOONNVFMA-UHFFFAOYSA-N
SMILES COC(=O)CCCC(=O)OC
LogP 0.49 at 20℃
CAS DataBase Reference 1119-40-0(CAS DataBase Reference)
Indirect Additives used in Food Contact Substances DIMETHYL GLUTARATE
FDA 21 CFR 176.170
EWG's Food Scores 1
FDA UNII 1I9VFA346P
NIST Chemistry Reference Dimethyl pentanedioate(1119-40-0)
EPA Substance Registry System Dimethyl glutarate (1119-40-0)
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-24/25
WGK Germany  1
Autoignition Temperature 365 °C
TSCA  TSCA listed
HS Code  29171990
Storage Class 10 - Combustible liquids
Hazardous Substances Data 1119-40-0(Hazardous Substances Data)
Toxicity LD50 orally in Rabbit: 8191 mg/kg LD50 dermal Rabbit > 2250 mg/kg
REACH Registrations Active
NFPA 704
1
1 0

Dimethyl Glutarate price More Price(46)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.14659 Dimethyl glutarate for synthesis 1119-40-0 250ML $51.4 2026-04-30 Buy
Sigma-Aldrich 8.14659 Dimethyl glutarate for synthesis 1119-40-0 1L $128 2026-04-30 Buy
Sigma-Aldrich D158801 DBE-5 dibasic ester 99% 1119-40-0 100g $70.3 2023-01-07 Buy
TCI Chemical G0185 Dimethyl Glutarate >98.0%(GC) 1119-40-0 25g $25 2026-04-30 Buy
TCI Chemical G0185 Dimethyl Glutarate >98.0%(GC) 1119-40-0 100g $50 2026-04-30 Buy
Product number Packaging Price Buy
8.14659 250ML $51.4 Buy
8.14659 1L $128 Buy
D158801 100g $70.3 Buy
G0185 25g $25 Buy
G0185 100g $50 Buy

Dimethyl Glutarate Chemical Properties,Uses,Production

General Description

Dimethyl glutarate, also known as glutaric acid dimethyl ester, dimethyl ester, pentanedioic acid, or dimethyl pentanedioate is an organic chemical with the molecular formula C7H12O4. It has a faint agreeable odor and is very soluble in alcohol and ether.

Uses

Industrial Uses
Dimethyl glutarate is used as an intermediate and solvent in the packing and formulation of mixtures and substances. It is also used as an intermediate in the manufacture of cleaning agents, lubricants, coating agents, rolling oils, metal working fluids, blowing agents, functional fluids.
The compound is used in laboratories, polymer processing, water treatment chemicals, rubber production and processing.
Uses by professional Workers
Dimethyl glutarate is used in gas and oil field production and drilling operations. It is used in de-icing and anti-icing applications, construction and road applications, and release and binders agents.
Consumer Uses
The compound is used in the manufacture of agrochemicals and water treatment chemicals.

Chemical Properties

CLEAR COLOURLESS LIQUID

Uses

Dimethyl glutarate is applied as paint and graffiti removers, nail polish removers, hand cleaners, adhesives, sealants and caulks, automotive cleaning products, bathroom and tile cleaners, general purpose cleaners, spot removers, floor maintenance products.

Synthesis Reference(s)

Synthesis, p. 555, 1985 DOI: 10.1055/s-1985-31275

General Description

Colorless liquid.

Air & Water Reactions

Flammable. Hydrolyzed by strong mineral acids and strong alkalis.

Reactivity Profile

Dimethyl Glutarate is an ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.

Health Hazard

May be harmful by inhalation, ingestion, or skin absorption. May cause irritation.

Flammability and Explosibility

Non flammable

Safety

Dimethyl Glutarate belongs to the class of organic compounds known as fatty acid methyl esters. Fatty acid methyl esters are compounds containing a fatty acid that is esterified with a methyl group. They have the general structure RC(=O)OR', where R=fatty aliphatic tail or organyl group and R'=methyl group. DIMETHYL GLUTARATE is an extremely weak basic (essentially neutral) compound (based on its pKa). This compound has been identified in human blood as reported by (PMID: 31557052 ). Dimethyl glutarate is not a naturally occurring metabolite and is only found in those individuals exposed to this compound or its derivatives. Technically Dimethyl glutarate is part of the human exposome. The exposome can be defined as the collection of all the exposures of an individual in a lifetime and how those exposures relate to health. An individual's exposure begins before birth and includes insults from environmental and occupational sources.

Synthesis

Methanol

67-56-1

Glutaric acid

110-94-1

Dimethyl Glutarate

1119-40-0

Phosphorus trichloride (PCl3, 8 mL) was added dropwise to a methanol (50 mL) solution of glutaric acid (13.2 g, 0.10 mol) under ice-bath cooling and continuous stirring. Upon completion of the reaction, the solvent was removed from the reaction mixture under reduced pressure. Subsequently, the resulting residue was distilled under reduced pressure. Fractions with boiling points of 110-112 °C were collected to give dimethyl glutarate in a yield of 14.7 g and 92% yield.

Structure and conformation

Dimethyl glutarate (DM) contains two carbonyl groups and exhibits a symmetrical structure. In terms of molecular electrostatics, the two carbonyl oxygen atoms have identical electronegativity. As a result, when coordinating with lithium ions, these oxygen atoms display equivalent reactivity, facilitating the formation of various coordination structures—including chelation, bridging, and monodentate coordination—that significantly enhance the high-voltage stability of the electrolyte.

Toxics Screening Level

The ITSL for Dimethyl Glutarate is 0.5 μg/m3 based on annual averaging time.

References

[1] Analytical Chemistry, 2004, vol. 76, # 16, p. 4765 - 4778
[2] Patent: US2016/31858, 2016, A1. Location in patent: Paragraph 0143
[3] Recueil des Travaux Chimiques des Pays-Bas, 1899, vol. 18, p. 373
[4] Chem. Zentralbl., 1918, vol. 89, # I, p. 1144
[5] Recueil des Travaux Chimiques des Pays-Bas, 1926, vol. 45, p. 586

67-56-1
108-55-4
1119-40-0
Synthesis of Dimethyl Glutarate from Methanol and Glutaric anhydride
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